CH445500A - Verfahren zur Herstellung von Benzodiazepin-Derivaten - Google Patents

Verfahren zur Herstellung von Benzodiazepin-Derivaten

Info

Publication number
CH445500A
CH445500A CH288462A CH288462A CH445500A CH 445500 A CH445500 A CH 445500A CH 288462 A CH288462 A CH 288462A CH 288462 A CH288462 A CH 288462A CH 445500 A CH445500 A CH 445500A
Authority
CH
Switzerland
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CH288462A
Other languages
English (en)
Inventor
Henryk Sternbach Leo
Stempel Arthur
Artell Smith Franklin
Sidney Sach George
Saucy Gabriel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US114038A external-priority patent/US3153082A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to US617458A priority Critical patent/US3499027A/en
Publication of CH445500A publication Critical patent/CH445500A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH288462A 1961-03-20 1962-03-09 Verfahren zur Herstellung von Benzodiazepin-Derivaten CH445500A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US617458A US3499027A (en) 1962-03-09 1967-02-21 Intermediates for preparing certain 1,4-benzodiazepin-2-(1h)-ones

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9666361A 1961-03-20 1961-03-20
US114038A US3153082A (en) 1961-06-01 1961-06-01 2-amino-benzophenones

Publications (1)

Publication Number Publication Date
CH445500A true CH445500A (de) 1967-10-31

Family

ID=26791934

Family Applications (2)

Application Number Title Priority Date Filing Date
CH551966A CH459239A (de) 1961-03-20 1962-03-09 Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH288462A CH445500A (de) 1961-03-20 1962-03-09 Verfahren zur Herstellung von Benzodiazepin-Derivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH551966A CH459239A (de) 1961-03-20 1962-03-09 Verfahren zur Herstellung von Benzodiazepin-Derivaten

Country Status (5)

Country Link
BE (1) BE615194A (de)
CH (2) CH459239A (de)
ES (1) ES275601A1 (de)
GB (2) GB985657A (de)
SE (1) SE301974B (de)

Also Published As

Publication number Publication date
CH459239A (de) 1968-07-15
GB985658A (en) 1965-03-10
DE1445858B2 (de) 1975-07-03
BE615194A (fr) 1962-09-17
DE1445858A1 (de) 1969-01-16
GB985657A (en) 1965-03-10
ES275601A1 (es) 1962-09-16
SE301974B (de) 1968-07-01

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