CH445500A - Process for the preparation of benzodiazepine derivatives - Google Patents

Process for the preparation of benzodiazepine derivatives

Info

Publication number
CH445500A
CH445500A CH288462A CH288462A CH445500A CH 445500 A CH445500 A CH 445500A CH 288462 A CH288462 A CH 288462A CH 288462 A CH288462 A CH 288462A CH 445500 A CH445500 A CH 445500A
Authority
CH
Switzerland
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CH288462A
Other languages
German (de)
Inventor
Henryk Sternbach Leo
Stempel Arthur
Artell Smith Franklin
Sidney Sach George
Saucy Gabriel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US114038A external-priority patent/US3153082A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to US617458A priority Critical patent/US3499027A/en
Publication of CH445500A publication Critical patent/CH445500A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH288462A 1961-03-20 1962-03-09 Process for the preparation of benzodiazepine derivatives CH445500A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US617458A US3499027A (en) 1962-03-09 1967-02-21 Intermediates for preparing certain 1,4-benzodiazepin-2-(1h)-ones

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9666361A 1961-03-20 1961-03-20
US114038A US3153082A (en) 1961-06-01 1961-06-01 2-amino-benzophenones

Publications (1)

Publication Number Publication Date
CH445500A true CH445500A (en) 1967-10-31

Family

ID=26791934

Family Applications (2)

Application Number Title Priority Date Filing Date
CH288462A CH445500A (en) 1961-03-20 1962-03-09 Process for the preparation of benzodiazepine derivatives
CH551966A CH459239A (en) 1961-03-20 1962-03-09 Process for the preparation of benzodiazepine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH551966A CH459239A (en) 1961-03-20 1962-03-09 Process for the preparation of benzodiazepine derivatives

Country Status (5)

Country Link
BE (1) BE615194A (en)
CH (2) CH445500A (en)
ES (1) ES275601A1 (en)
GB (2) GB985658A (en)
SE (1) SE301974B (en)

Also Published As

Publication number Publication date
DE1445858A1 (en) 1969-01-16
SE301974B (en) 1968-07-01
GB985657A (en) 1965-03-10
DE1445858B2 (en) 1975-07-03
ES275601A1 (en) 1962-09-16
BE615194A (en) 1962-09-17
CH459239A (en) 1968-07-15
GB985658A (en) 1965-03-10

Similar Documents

Publication Publication Date Title
CH445502A (en) Process for the preparation of benzodiazepine derivatives
CH429724A (en) Process for the preparation of thiaxanthene derivatives
CH460794A (en) Process for the preparation of benzodiazepine derivatives
CH436316A (en) Process for the preparation of benzodiazepine derivatives
CH428767A (en) Process for the preparation of 1-phenyl-2-aminoethanol derivatives
CH457465A (en) Process for the preparation of benzodiazepine derivatives
CH442326A (en) Process for the preparation of benzodiazepine derivatives
CH440298A (en) Process for the preparation of benzodiazepine derivatives
CH439326A (en) Process for the preparation of phenyl-propylamine derivatives
CH415674A (en) Process for the preparation of derivatives of 3-phenyl-7-oxychromone
CH458374A (en) Process for the preparation of benzodiazepine derivatives
CH438336A (en) Process for the preparation of benzodiazepine derivatives
CH436315A (en) Process for the preparation of benzodiazepine derivatives
AT238201B (en) Process for the preparation of quinolizine derivatives
CH413842A (en) Process for the preparation of quinolizine derivatives
CH454888A (en) Process for the preparation of benzodiazepine derivatives
AT225700B (en) Process for the preparation of phenylalkanolamine derivatives
CH420176A (en) Process for the preparation of benzodiazepine derivatives
CH445500A (en) Process for the preparation of benzodiazepine derivatives
CH418344A (en) Process for the preparation of benzodiazepine derivatives
CH411912A (en) Process for the preparation of benzodiazepine derivatives
CH469012A (en) Process for the preparation of benzodiazepine derivatives
CH421111A (en) Process for the preparation of derivatives of the 4-azaphenthiazines
AT232512B (en) Process for the preparation of amino-dithiohydroquinone derivatives
CH438291A (en) Process for the preparation of 2a-methylandrostane derivatives