ES2750258T3 - Métodos y composiciones para la prevención o tratamiento del síndrome de Barth - Google Patents

Métodos y composiciones para la prevención o tratamiento del síndrome de Barth Download PDF

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Publication number
ES2750258T3
ES2750258T3 ES14756991T ES14756991T ES2750258T3 ES 2750258 T3 ES2750258 T3 ES 2750258T3 ES 14756991 T ES14756991 T ES 14756991T ES 14756991 T ES14756991 T ES 14756991T ES 2750258 T3 ES2750258 T3 ES 2750258T3
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ES
Spain
Prior art keywords
peptide
subject
barth syndrome
aromatic
arg
Prior art date
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Active
Application number
ES14756991T
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English (en)
Spanish (es)
Inventor
D Travis Wilson
Mark Bamberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stealth Biotherapeutics Corp
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Stealth Biotherapeutics Corp
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES14756991T 2013-03-01 2014-02-28 Métodos y composiciones para la prevención o tratamiento del síndrome de Barth Active ES2750258T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361771642P 2013-03-01 2013-03-01
US201361771534P 2013-03-01 2013-03-01
US201361839753P 2013-06-26 2013-06-26
PCT/US2014/019622 WO2014134554A1 (en) 2013-03-01 2014-02-28 Methods and compositions for the prevention or treatment of barth syndrome

Publications (1)

Publication Number Publication Date
ES2750258T3 true ES2750258T3 (es) 2020-03-25

Family

ID=51428869

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14756991T Active ES2750258T3 (es) 2013-03-01 2014-02-28 Métodos y composiciones para la prevención o tratamiento del síndrome de Barth

Country Status (9)

Country Link
US (5) US9687519B2 (cg-RX-API-DMAC7.html)
EP (2) EP3626252A1 (cg-RX-API-DMAC7.html)
JP (4) JP6518197B2 (cg-RX-API-DMAC7.html)
CN (3) CN115990242A (cg-RX-API-DMAC7.html)
CA (1) CA2916880C (cg-RX-API-DMAC7.html)
DK (1) DK2961420T3 (cg-RX-API-DMAC7.html)
ES (1) ES2750258T3 (cg-RX-API-DMAC7.html)
HU (1) HUE046924T2 (cg-RX-API-DMAC7.html)
WO (1) WO2014134554A1 (cg-RX-API-DMAC7.html)

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EP3626252A1 (en) 2013-03-01 2020-03-25 Stealth Biotherapeutics Corp Methods and compositions for the prevention or treatment of barth syndrome
DK2961378T3 (da) 2013-03-01 2019-11-25 Stealth Biotherapeutics Corp Fremgangsmåder til behandlingen af mitochondrisk sygdom
CA2916977A1 (en) * 2013-06-26 2014-12-31 Stealth Biotherapeutics Corp Methods and compositions for detecting and diagnosing diseases and conditions
US9550981B2 (en) 2014-01-22 2017-01-24 University Of Washington Modified tafazzin proteins and methods of making and using the same
US10086040B2 (en) 2014-12-12 2018-10-02 University Of Washington Methods for treating and preventing cardiomyopathy with a fusion protein of tafazzin and a cellular permeability peptide
WO2018104172A1 (en) 2016-12-06 2018-06-14 Centre National De La Recherche Scientifique (Cnrs) Compounds for treating barth syndrome
IL322723A (en) 2017-04-05 2025-10-01 Stealth Biotherapeutics Inc Crystalline salt forms of boc-d-arg-dmt-lys-(boc)-phe-nh2
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
WO2020131283A1 (en) * 2018-12-18 2020-06-25 Stealth Biotherapeutics Corp. Analogs that target mitochondrial diseases

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Also Published As

Publication number Publication date
EP2961420A1 (en) 2016-01-06
JP2016511259A (ja) 2016-04-14
US20180147251A1 (en) 2018-05-31
JP6518197B2 (ja) 2019-05-22
US11083772B2 (en) 2021-08-10
EP3626252A1 (en) 2020-03-25
CN115990242A (zh) 2023-04-21
EP2961420B1 (en) 2019-09-11
CN115990241A (zh) 2023-04-21
DK2961420T3 (da) 2019-10-07
JP7072692B2 (ja) 2022-05-20
JP2022116008A (ja) 2022-08-09
US20210401923A1 (en) 2021-12-30
EP2961420A4 (en) 2016-08-17
WO2014134554A1 (en) 2014-09-04
US12268724B2 (en) 2025-04-08
US11083771B2 (en) 2021-08-10
JP2019147815A (ja) 2019-09-05
JP2021098704A (ja) 2021-07-01
US20160228487A1 (en) 2016-08-11
US11771734B2 (en) 2023-10-03
US20240156892A1 (en) 2024-05-16
CA2916880C (en) 2021-02-09
US9687519B2 (en) 2017-06-27
HUE046924T2 (hu) 2020-03-30
CN105407906A (zh) 2016-03-16
CA2916880A1 (en) 2014-09-04
JP7381652B2 (ja) 2023-11-15
JP6918046B2 (ja) 2021-08-11
US20200345803A1 (en) 2020-11-05

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