ES274967A1 - Procedure for the manufacture of new fenotiazine compounds (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the manufacture of new fenotiazine compounds (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES274967A1
ES274967A1 ES0274967A ES274967A ES274967A1 ES 274967 A1 ES274967 A1 ES 274967A1 ES 0274967 A ES0274967 A ES 0274967A ES 274967 A ES274967 A ES 274967A ES 274967 A1 ES274967 A1 ES 274967A1
Authority
ES
Spain
Prior art keywords
general formula
compound
see formula
phenothiazine
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0274967A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US91603A external-priority patent/US3238199A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES274967A1 publication Critical patent/ES274967A1/en
Expired legal-status Critical Current

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/584Recycling of catalysts

Landscapes

  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Process for the manufacture of new phenothiazine compounds, characterized in that it comprises reacting a compound of the general formula ** (See formula) ** with a compound of the general formula ** (See formula) ** or reacting 2-trifluoromethyl-phenothiazine, in the presence of an acid-binding agent, with a reactive ester of a compound of the general formula ** (See formula) ** or treating 2-trifluoromethyl-phenothiazine with phosgene, reacting the 2-trifluoromethyl-10-cyclocarbonyl-phenothiazine formed with a compound of the general formula ** (See formula) ** and the decarboxylation by heating the product obtained, or reacting a reactive ester of a compound of the general formula ** (See formula) ** with an amine of the general formula ** (See formula) ** in which formulas n represents 1 or 2, one of the symbols n1 and n2 represents 0 while the other symbol represents 0 or 1, one of the symbols X and Y represents halogen, while the other represents the group -OMe, in which Me represents an alkali metal, A and B represent lower straight or branched chain lower alkylene, and R1 and R2 represent lower alkyl or, taken together with nitrogen, a 5- or 6-membered heterocyclic containing 1 or 2 nitrogen atoms, or a 5- or 6-membered heterocyclic ring, substituted by lower alkyl and containing 1 or 2 nitrogen atoms, in which case one of the alkyl radicals represented by the symbols R1 and R2 can be introduced later into the molecule by reaction of the secondary amine with a low molecular weight alkylating agent, and, if desired, transforming into a salt the product obtained. (Machine-translation by Google Translate, not legally binding)
ES0274967A 1961-02-27 1962-02-26 Procedure for the manufacture of new fenotiazine compounds (Machine-translation by Google Translate, not legally binding) Expired ES274967A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91603A US3238199A (en) 1961-02-27 1961-02-27 Phenothiazine compounds

Publications (1)

Publication Number Publication Date
ES274967A1 true ES274967A1 (en) 1962-10-01

Family

ID=34632440

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0274967A Expired ES274967A1 (en) 1961-02-27 1962-02-26 Procedure for the manufacture of new fenotiazine compounds (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
BE (1) BE614129A (en)
ES (1) ES274967A1 (en)

Also Published As

Publication number Publication date
BE614129A (en) 1962-06-20

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