ES318487A1 - Procedure for the preparation of new derivatives of sulfanilamide. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new derivatives of sulfanilamide. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES318487A1
ES318487A1 ES0318487A ES318487A ES318487A1 ES 318487 A1 ES318487 A1 ES 318487A1 ES 0318487 A ES0318487 A ES 0318487A ES 318487 A ES318487 A ES 318487A ES 318487 A1 ES318487 A1 ES 318487A1
Authority
ES
Spain
Prior art keywords
radical
amine group
compound
formula
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0318487A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES318487A1 publication Critical patent/ES318487A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69Benzenesulfonamido-pyrimidines

Abstract

Process for the preparation of new sulfanilamide derivatives corresponding to the general formula I ** (See formula) ** where R1 and R2 signify, independently of one another, hydrogen, an alkyl, alkoxy or lower alkylthio radical, the cyclopropyl radical or a halogen atom and R3 means hydrogen or the cyclopropyl radical, wherein only one of the radicals R1, R2 or R3 is a cyclopropyl radical, characterized in that a compound of the general formula II is reacted ** (See formula) ** with a compound of formula III ** (See formula) ** where X means the amine group or a nitrogenous group convertible into amine group, one of the two symbols A1 and A2 means the amine group -NH- and the other means the direct bond, Z and X together represent dissociable reactive radicals and R1, R2 and R3 have the meaning set forth above, optionally in the presence of an acid-accepting agent, to form a compound of the general formula IV ** (See formula) ** where R1, R2, R3 and X have the meaning set forth above, convert, if necessary, the group X of the product of the reaction into free amine group and/or react, if desired, a product of the reaction containing as radical R1 and/or R2 a halogen atom (in particular a chlorine atom), with a metal compound of a lower alkanol or alkanol or reduced to remove the halogen atom, or the halogen atoms, R1 and/or R2. (Machine-translation by Google Translate, not legally binding)
ES0318487A 1964-10-15 1965-10-14 Procedure for the preparation of new derivatives of sulfanilamide. (Machine-translation by Google Translate, not legally binding) Expired ES318487A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1341064A CH443311A (en) 1964-10-15 1964-10-15 Process for the preparation of new derivatives of sulfanilamide

Publications (1)

Publication Number Publication Date
ES318487A1 true ES318487A1 (en) 1966-06-01

Family

ID=4392172

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0318487A Expired ES318487A1 (en) 1964-10-15 1965-10-14 Procedure for the preparation of new derivatives of sulfanilamide. (Machine-translation by Google Translate, not legally binding)

Country Status (9)

Country Link
AT (1) AT256852B (en)
BE (1) BE670903A (en)
CH (1) CH443311A (en)
DK (1) DK109600C (en)
ES (1) ES318487A1 (en)
FR (1) FR5377M (en)
GB (1) GB1059719A (en)
NL (1) NL6513321A (en)
SE (1) SE306320B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500993A (en) * 1966-04-13 1970-12-31 Ciba Geigy Ag Process for the preparation of new derivatives of sulfanilamide
US3683082A (en) * 1970-02-09 1972-08-08 Geigy Chem Corp N-acetyl-n-(cyclopropyl-4-pyrimidinyl)-sulphanilamides as antibacterial agents

Also Published As

Publication number Publication date
AT256852B (en) 1967-09-11
CH443311A (en) 1967-09-15
BE670903A (en) 1966-04-14
NL6513321A (en) 1966-04-18
SE306320B (en) 1968-11-25
DK109600C (en) 1968-05-20
FR5377M (en) 1967-09-18
GB1059719A (en) 1967-02-22

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