ES2733767T3 - Método para la fabricación de derivados de hidroxietilalmidón - Google Patents
Método para la fabricación de derivados de hidroxietilalmidón Download PDFInfo
- Publication number
- ES2733767T3 ES2733767T3 ES12737229T ES12737229T ES2733767T3 ES 2733767 T3 ES2733767 T3 ES 2733767T3 ES 12737229 T ES12737229 T ES 12737229T ES 12737229 T ES12737229 T ES 12737229T ES 2733767 T3 ES2733767 T3 ES 2733767T3
- Authority
- ES
- Spain
- Prior art keywords
- value
- temperature
- solution
- iron
- hydroxyethyl starch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/08—Ethers
- C08B31/12—Ethers having alkyl or cycloalkyl radicals substituted by heteroatoms, e.g. hydroxyalkyl or carboxyalkyl starch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/08—Ethers
- C08B31/10—Alkyl or cycloalkyl ethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
- C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11170761A EP2537866A1 (en) | 2011-06-21 | 2011-06-21 | Hydroxyethyl starch derivatives, method for manufacturing the same and therapeutical uses thereof |
| PCT/EP2012/061958 WO2012175608A1 (en) | 2011-06-21 | 2012-06-21 | Method for manufacturing hydroxyethyl starch derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2733767T3 true ES2733767T3 (es) | 2019-12-02 |
Family
ID=44799422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12737229T Active ES2733767T3 (es) | 2011-06-21 | 2012-06-21 | Método para la fabricación de derivados de hidroxietilalmidón |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9181353B2 (https=) |
| EP (2) | EP2537866A1 (https=) |
| JP (2) | JP6370217B2 (https=) |
| CN (2) | CN103649128B (https=) |
| BR (1) | BR112013032901A2 (https=) |
| CA (1) | CA2837784C (https=) |
| CY (1) | CY1121976T1 (https=) |
| DK (1) | DK2723774T3 (https=) |
| ES (1) | ES2733767T3 (https=) |
| HK (1) | HK1220218A1 (https=) |
| HR (1) | HRP20191173T1 (https=) |
| HU (1) | HUE044428T2 (https=) |
| LT (1) | LT2723774T (https=) |
| MX (1) | MX337682B (https=) |
| PL (1) | PL2723774T3 (https=) |
| PT (1) | PT2723774T (https=) |
| RS (1) | RS59021B1 (https=) |
| SI (1) | SI2723774T1 (https=) |
| SM (1) | SMT201900430T1 (https=) |
| TR (1) | TR201909574T4 (https=) |
| TW (1) | TWI564010B (https=) |
| WO (1) | WO2012175608A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6616725B2 (ja) * | 2016-03-31 | 2019-12-04 | 日本製紙株式会社 | 塗工紙用澱粉 |
| AU2020206021B2 (en) | 2019-01-10 | 2025-05-08 | Pharmacosmos Holding A/S | Treating iron deficiency in subjects at risk of cardiovascular adverse events and iron for the management of atrial fibrillation |
| EA202191858A1 (ru) | 2019-06-12 | 2021-11-12 | Фармакосмос Холдинг А/С | Лечение дефицита железа у субъектов с риском нежелательных явлений со стороны сердечно-сосудистой системы и железо для лечения фибрилляции предсердий |
| JP2024529536A (ja) | 2021-08-03 | 2024-08-06 | ファーマコスモス ホールディング エー／エス | コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物 |
| CN117547549A (zh) * | 2023-11-09 | 2024-02-13 | 黑龙江八一农垦大学 | 适用于犬arf的腹膜透析液与助清除剂的制备方法 |
| CA3280511A1 (en) | 2024-07-18 | 2026-03-01 | Malian Biologicals Gmbh | Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases and iron supplementation in neurodevelopmental or psychiatric disorder |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3639588A (en) * | 1966-10-22 | 1972-02-01 | Fisons Pharmaceuticals Ltd | Pharmaceutical compositions containing ferric hydroxide complexed with dextran or dextrin heptonic acids |
| US4370476A (en) * | 1979-07-17 | 1983-01-25 | Usher Thomas C | Dextran polycarboxylic acids, ferric hydroxide complexes |
| GB8902894D0 (en) * | 1989-02-09 | 1989-03-30 | Fisons Plc | Compositions |
| JPH0566372A (ja) * | 1991-09-10 | 1993-03-19 | Fukui Megane Kogyo Kk | 金属製眼鏡フレーム部品の製造方法 |
| JPH0776524A (ja) * | 1993-07-13 | 1995-03-20 | Takeda Chem Ind Ltd | 動物用抗貧血剤 |
| DK172860B1 (da) * | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
| DK173138B1 (da) * | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
| EP1762250A1 (en) | 2005-09-12 | 2007-03-14 | Fresenius Kabi Deutschland GmbH | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine |
| US9080133B2 (en) * | 2007-08-17 | 2015-07-14 | Akzo Nobel N.V. | Glutamic acid N,N-diacetic amide, glutamic acid N-acetic amide N-acetonitrile, alkali metal salts thereof, process to prepare them and their use |
| TWI469965B (zh) * | 2008-12-22 | 2015-01-21 | Ono Pharmaceutical Co | 乙炔基吲哚化合物 |
| JP5397991B2 (ja) * | 2009-04-01 | 2014-01-22 | 学校法人東京農業大学 | 乳酸菌を用いたビタミンｂ１２の定量方法 |
-
2011
- 2011-06-21 EP EP11170761A patent/EP2537866A1/en not_active Withdrawn
-
2012
- 2012-06-21 CN CN201280029882.3A patent/CN103649128B/zh active Active
- 2012-06-21 US US14/127,766 patent/US9181353B2/en active Active
- 2012-06-21 LT LTEP12737229.0T patent/LT2723774T/lt unknown
- 2012-06-21 SM SM20190430T patent/SMT201900430T1/it unknown
- 2012-06-21 TR TR2019/09574T patent/TR201909574T4/en unknown
- 2012-06-21 CN CN201510909616.5A patent/CN105348401A/zh active Pending
- 2012-06-21 EP EP12737229.0A patent/EP2723774B1/en active Active
- 2012-06-21 PL PL12737229T patent/PL2723774T3/pl unknown
- 2012-06-21 CA CA2837784A patent/CA2837784C/en active Active
- 2012-06-21 MX MX2013015075A patent/MX337682B/es active IP Right Grant
- 2012-06-21 BR BR112013032901A patent/BR112013032901A2/pt active IP Right Grant
- 2012-06-21 PT PT12737229T patent/PT2723774T/pt unknown
- 2012-06-21 ES ES12737229T patent/ES2733767T3/es active Active
- 2012-06-21 JP JP2014516345A patent/JP6370217B2/ja active Active
- 2012-06-21 HR HRP20191173TT patent/HRP20191173T1/hr unknown
- 2012-06-21 WO PCT/EP2012/061958 patent/WO2012175608A1/en not_active Ceased
- 2012-06-21 RS RS20190850A patent/RS59021B1/sr unknown
- 2012-06-21 HU HUE12737229 patent/HUE044428T2/hu unknown
- 2012-06-21 TW TW101122208A patent/TWI564010B/zh active
- 2012-06-21 SI SI201231627T patent/SI2723774T1/sl unknown
- 2012-06-21 DK DK12737229.0T patent/DK2723774T3/da active
-
2015
- 2015-10-26 US US14/922,897 patent/US9631032B2/en active Active
-
2016
- 2016-07-12 HK HK16108112.8A patent/HK1220218A1/zh unknown
-
2018
- 2018-03-27 JP JP2018059264A patent/JP2018100424A/ja active Pending
-
2019
- 2019-07-03 CY CY20191100704T patent/CY1121976T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LT2723774T (lt) | 2019-08-12 |
| SMT201900430T1 (it) | 2019-09-09 |
| PT2723774T (pt) | 2019-07-15 |
| SI2723774T1 (sl) | 2019-08-30 |
| EP2723774B1 (en) | 2019-04-03 |
| CN103649128B (zh) | 2016-02-10 |
| RS59021B1 (sr) | 2019-08-30 |
| TW201315474A (zh) | 2013-04-16 |
| CA2837784A1 (en) | 2012-12-27 |
| WO2012175608A1 (en) | 2012-12-27 |
| HUE044428T2 (hu) | 2019-10-28 |
| EP2537866A1 (en) | 2012-12-26 |
| TR201909574T4 (en) | 2019-08-21 |
| BR112013032901A2 (pt) | 2017-01-24 |
| HRP20191173T1 (hr) | 2019-10-04 |
| CY1121976T1 (el) | 2020-10-14 |
| CN105348401A (zh) | 2016-02-24 |
| US9631032B2 (en) | 2017-04-25 |
| CA2837784C (en) | 2019-10-15 |
| MX2013015075A (es) | 2014-04-14 |
| TWI564010B (zh) | 2017-01-01 |
| HK1220218A1 (zh) | 2017-04-28 |
| US20140128594A1 (en) | 2014-05-08 |
| PL2723774T3 (pl) | 2019-10-31 |
| US20160046733A1 (en) | 2016-02-18 |
| EP2723774A1 (en) | 2014-04-30 |
| DK2723774T3 (da) | 2019-07-15 |
| JP2014520188A (ja) | 2014-08-21 |
| MX337682B (es) | 2016-03-15 |
| CN103649128A (zh) | 2014-03-19 |
| JP6370217B2 (ja) | 2018-08-08 |
| JP2018100424A (ja) | 2018-06-28 |
| US9181353B2 (en) | 2015-11-10 |
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