ES2728119T3 - Identificación de estados celulares funcionales - Google Patents

Identificación de estados celulares funcionales Download PDF

Info

Publication number
ES2728119T3
ES2728119T3 ES15702063T ES15702063T ES2728119T3 ES 2728119 T3 ES2728119 T3 ES 2728119T3 ES 15702063 T ES15702063 T ES 15702063T ES 15702063 T ES15702063 T ES 15702063T ES 2728119 T3 ES2728119 T3 ES 2728119T3
Authority
ES
Spain
Prior art keywords
cells
cell
parameter
phenotypic
response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15702063T
Other languages
English (en)
Spanish (es)
Inventor
Bartlomiej Rajwa
T Vincent Shankey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASEDASCIENCES AG
Original Assignee
ASEDASCIENCES AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASEDASCIENCES AG filed Critical ASEDASCIENCES AG
Application granted granted Critical
Publication of ES2728119T3 publication Critical patent/ES2728119T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00Subject matter not provided for in other groups of this subclass
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5026Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/30Prediction of properties of chemical compounds, compositions or mixtures
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/40Searching chemical structures or physicochemical data
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00Subject matter not provided for in other groups of this subclass

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Computing Systems (AREA)
  • Physiology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
ES15702063T 2014-01-14 2015-01-14 Identificación de estados celulares funcionales Active ES2728119T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461927247P 2014-01-14 2014-01-14
PCT/US2015/011441 WO2015109003A1 (en) 2014-01-14 2015-01-14 Identification of functional cell states

Publications (1)

Publication Number Publication Date
ES2728119T3 true ES2728119T3 (es) 2019-10-22

Family

ID=52440877

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15702063T Active ES2728119T3 (es) 2014-01-14 2015-01-14 Identificación de estados celulares funcionales

Country Status (11)

Country Link
US (3) US20150198584A1 (cg-RX-API-DMAC7.html)
EP (1) EP3094974B1 (cg-RX-API-DMAC7.html)
JP (1) JP6606100B2 (cg-RX-API-DMAC7.html)
KR (1) KR102413041B1 (cg-RX-API-DMAC7.html)
AU (2) AU2015206520B2 (cg-RX-API-DMAC7.html)
CA (1) CA2972960C (cg-RX-API-DMAC7.html)
DK (1) DK3094974T3 (cg-RX-API-DMAC7.html)
ES (1) ES2728119T3 (cg-RX-API-DMAC7.html)
IL (1) IL246734B (cg-RX-API-DMAC7.html)
SG (1) SG11201705495XA (cg-RX-API-DMAC7.html)
WO (1) WO2015109003A1 (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2972960C (en) * 2014-01-14 2022-01-11 Asedasciences Ag Identification of functional cell states
JP6544600B2 (ja) 2015-02-24 2019-07-17 国立大学法人 東京大学 動的高速高感度イメージング装置及びイメージング方法
WO2017073737A1 (ja) 2015-10-28 2017-05-04 国立大学法人東京大学 分析装置
US10824693B2 (en) * 2015-12-10 2020-11-03 Reservoir Labs, Inc. Systems and methods for selective expansive recursive tensor analysis
US11205103B2 (en) 2016-12-09 2021-12-21 The Research Foundation for the State University Semisupervised autoencoder for sentiment analysis
US12300357B2 (en) 2016-12-14 2025-05-13 FlowJo, LLC Applied computer technology for management, synthesis, visualization, and exploration of parameters in large multi-parameter data sets
US11573182B2 (en) 2017-05-25 2023-02-07 FlowJo, LLC Visualization, comparative analysis, and automated difference detection for large multi-parameter data sets
CN112638529B (zh) 2018-06-13 2023-05-30 新克赛特株式会社 细胞计数的方法和系统
EP3969978B1 (en) * 2019-05-14 2025-10-01 University of Pittsburgh - of the Commonwealth System of Higher Education System and method for characterizing cellular phenotypic diversity from multi-parameter cellular. and sub-cellular imaging data
CN114930150A (zh) 2019-12-27 2022-08-19 新克赛特株式会社 评估流式细胞仪性能的方法和标准粒子悬浮液
WO2021200960A1 (ja) 2020-04-01 2021-10-07 シンクサイト株式会社 観察装置
CN115349083B (zh) 2020-04-01 2025-11-04 新克赛特株式会社 流式细胞仪
WO2022026532A1 (en) * 2020-07-30 2022-02-03 Allen Institute Systems, devices, and methods for compound screening using predictive tagging
US20240337647A1 (en) 2021-07-26 2024-10-10 Asedasciences Ag Improved methods for identification of functional cell states
WO2023056481A1 (en) * 2021-10-01 2023-04-06 CAP Diagnostics, LLC, dba Pathnostics Automated methods and systems for rapid identification of target particles
US12105081B2 (en) * 2021-10-20 2024-10-01 Travera, Inc. Treatment response assessment using normalized single cell measurements
IL322273A (en) 2023-01-23 2025-09-01 Asedasciences Ag Improved human-computer interaction systems

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5544650A (en) 1988-04-08 1996-08-13 Neuromedical Systems, Inc. Automated specimen classification system and method
WO1994016314A1 (en) 1993-01-08 1994-07-21 Coulter Corporation Method of using preserved control cells in the calibration of fluorescent and light scatter measurements
CA2196496A1 (en) 1997-01-31 1998-07-31 Stephen William Watson Michnick Protein fragment complementation assay for the detection of protein-protein interactions
US7166424B2 (en) 1998-02-02 2007-01-23 Odyssey Thera Inc. Fragments of fluorescent proteins for protein fragment complementation assays
US20050221280A1 (en) 1998-02-02 2005-10-06 Odyssey Thera, Inc. Protein-protein interactions for pharmacological profiling
US6801859B1 (en) 1998-12-23 2004-10-05 Rosetta Inpharmatics Llc Methods of characterizing drug activities using consensus profiles
US6998249B1 (en) 1999-09-27 2006-02-14 Pharmacia & Upjohn Company Toxicity screening method
ATE516497T1 (de) 2000-03-06 2011-07-15 Asterand Acquisition Llc Screening für funktionshomologien
AU2001263776A1 (en) 2000-06-02 2001-12-11 Medicometrics Aps Method and system for classifying a biological sample
US7146349B2 (en) 2000-11-06 2006-12-05 International Business Machines Corporation Network for describing multimedia information
EP1625394A4 (en) * 2003-04-23 2008-02-06 Bioseek Inc METHOD FOR ANALYZING BIOLOGICAL DATA PROFILES
EP1620722A4 (en) 2003-04-23 2008-01-30 Bioseek Inc METHODS FOR CHARACTERIZING SIGNALING PATHWAYS AND COMPOUNDS INTERACTING THEREWITH
WO2008134593A1 (en) 2007-04-25 2008-11-06 President And Fellows Of Harvard College Molecular circuits
US20130226469A1 (en) 2008-04-01 2013-08-29 Purdue Research Foundation Gate-free flow cytometry data analysis
WO2009146036A2 (en) 2008-04-01 2009-12-03 Purdue Research Foundation Quantification of differences between measured values and statistical validation based on the differences
CA2972960C (en) * 2014-01-14 2022-01-11 Asedasciences Ag Identification of functional cell states

Also Published As

Publication number Publication date
US20210364499A1 (en) 2021-11-25
US20150198584A1 (en) 2015-07-16
KR102413041B1 (ko) 2022-06-23
EP3094974A1 (en) 2016-11-23
AU2015206520A1 (en) 2016-07-14
KR20160110444A (ko) 2016-09-21
US20160370350A1 (en) 2016-12-22
AU2015206520B2 (en) 2021-07-22
IL246734A0 (en) 2016-08-31
HK1231553A1 (en) 2017-12-22
EP3094974B1 (en) 2019-02-27
JP6606100B2 (ja) 2019-11-13
AU2021204419A1 (en) 2021-07-22
JP2017505140A (ja) 2017-02-16
US11867690B2 (en) 2024-01-09
CA2972960A1 (en) 2015-07-23
IL246734B (en) 2019-06-30
SG11201705495XA (en) 2017-08-30
DK3094974T3 (da) 2019-05-27
CA2972960C (en) 2022-01-11
US11137388B2 (en) 2021-10-05
WO2015109003A1 (en) 2015-07-23

Similar Documents

Publication Publication Date Title
ES2728119T3 (es) Identificación de estados celulares funcionales
ES2980676T3 (es) Visualización, análisis comparativo y detección de diferencias automatizada para grandes conjuntos de datos multiparamétricos
US20240337647A1 (en) Improved methods for identification of functional cell states
Pirone et al. Beyond fluorescence: advances in computational label-free full specificity in 3D quantitative phase microscopy
Ahmed et al. Morphometric measurements of blood cell
KR20250048569A (ko) 이미징 기반 마이크로오가노스피어 약물 분석
Liu et al. Quantitative analysis of sperm plane circular movement in the blue mussels Mytilus edulis, M. trossulus and their hybrids
Charrasse et al. Quantitative assessment of mitochondrial morphology relevant for studies on cellular health and environmental toxicity
Charrasse et al. Quantitative imaging and semiotic phenotyping of mitochondrial network morphology in live human cells
Bourn et al. Evaluation of image analysis tools for the measurement of cellular morphology
Li et al. Detection and tracking of overlapping cell nuclei for large scale mitosis analyses
US20050282208A1 (en) Cellular phenotype
HK1231553B (en) Identification of functional cell states
Lippincott et al. High-content live-cell time-lapse imaging predicts cells about to die via apoptosis
Schauer et al. A novel organelle map framework for high-content cell morphology analysis in high throughput
US20230137843A1 (en) Holographic video microscopy cell viability assay
US20050014131A1 (en) Methods and apparatus for investigating side effects
Frey et al. Single-Cell Morphological Profiling Reveals Insights into Programmed Cell Death
Savatier et al. Monitoring cell cycle distributions in living cells by videomicrofluorometry and discriminant factorial analysis
Forsgren et al. The time dimension matters: Improving mode of action classification with live-cell imaging
US20240378908A1 (en) Computer-implemented method and corresponding apparatus for identifying subcellular structures in the non-chemical staining mode from phase contrast tomography reconstructions in flow cytometry
CN108267571A (zh) 一种血液种属判别的方法
Almagwashi Label-free detection of cell-cycling polyploid cells in osteosarcoma
WO2007030795A2 (en) Cellular phenotype
Wong et al. Enhanced Precision in Cell Culture Analytics: Leveraging Artificial Intelligence for Unbiased and Non-Destructive Assessment of Cell Growth and Viability.