ES2721513T3 - Método para tratar vejigas hiperactivas y un dispositivo para el almacenamiento y la administración de composiciones tópicas de oxibutinina - Google Patents

Método para tratar vejigas hiperactivas y un dispositivo para el almacenamiento y la administración de composiciones tópicas de oxibutinina Download PDF

Info

Publication number
ES2721513T3
ES2721513T3 ES17195548T ES17195548T ES2721513T3 ES 2721513 T3 ES2721513 T3 ES 2721513T3 ES 17195548 T ES17195548 T ES 17195548T ES 17195548 T ES17195548 T ES 17195548T ES 2721513 T3 ES2721513 T3 ES 2721513T3
Authority
ES
Spain
Prior art keywords
topical composition
weight
polymers
oxybutynin
occluded oxybutynin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17195548T
Other languages
English (en)
Inventor
Scott Gochnour
Venkatesh Subramanyan
Michael W Kimball
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Sales LLC
Original Assignee
Allergan Sales LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43050804&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2721513(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Sales LLC filed Critical Allergan Sales LLC
Application granted granted Critical
Publication of ES2721513T3 publication Critical patent/ES2721513T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D37/00—Sachet pads specially adapted for liquid toiletry or cosmetic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D17/00—Rigid or semi-rigid containers specially constructed to be opened by cutting or piercing, or by tearing of frangible members or portions
    • B65D17/28—Rigid or semi-rigid containers specially constructed to be opened by cutting or piercing, or by tearing of frangible members or portions at lines or points of weakness
    • B65D17/402—Rigid or semi-rigid containers specially constructed to be opened by cutting or piercing, or by tearing of frangible members or portions at lines or points of weakness characterised by having the line of weakness provided in the side wall

Abstract

Un sistema de embalaje que comprende: a) de 0,25 a 5 g de una composición tópica de oxibutinina no ocluida que comprende: i) del 2% en peso al 20% en peso de la composición tópica de oxibutinina; ii) del 0,05% en peso al 10% en peso de la composición tópica de un agente espesante seleccionado del grupo que consiste en polímeros sintéticos, polímeros de vinilo, polímeros de celulosa, agentes gelificantes de origen natural, compuestos de polietileno, polisacáridos, ésteres de ácido acrílico, polímeros de alcoxibutinina, polímeros de óxido de polietileno, poliéteres, succinato de gelatina, silicato de aluminio y magnesio coloidal, vaselina y mezclas de los mismos; y iii) 50% en peso o más de la composición tópica de un disolvente seleccionado del grupo que consiste en hidrocarburos C1-C6, agua y mezclas de los mismos; b) un depósito para la composición tópica de oxibutinina no ocluida; y c) un laminado que rodea el depósito y la composición tópica de oxibutinina no ocluida que comprende: i) una primera capa de polímero que está en contacto con la composición tópica de oxibutinina no ocluida, en la que la primera capa de polímero es un polímero o copolímero a base de polietileno o acrílico; y ii) una lámina metálica unida a la primera capa de polímero; y en donde el sistema de envasado puede soportar 206,84 kPa (30 libras) de presión sin estallar cuando se aprieta entre dos rodillos de un banco de pruebas motorizado, y cuando el sistema de envasado se almacena a 25°C y el 60% de humedad relativa durante veintiséis semanas, la composición tópica de oxibutinina ocluida no contiene más del 0,2% de éster etílico del ácido fenilciclohexilglicólico (PCGE); no más del 2,0% de ácido fenilciclohexilglicólico (PCGA) y no hay más de un 20% de cambio en el contenido de disolvente.
ES17195548T 2009-05-05 2010-05-04 Método para tratar vejigas hiperactivas y un dispositivo para el almacenamiento y la administración de composiciones tópicas de oxibutinina Active ES2721513T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/435,895 US8920392B2 (en) 2009-05-05 2009-05-05 Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions

Publications (1)

Publication Number Publication Date
ES2721513T3 true ES2721513T3 (es) 2019-08-01

Family

ID=43050804

Family Applications (2)

Application Number Title Priority Date Filing Date
ES17195548T Active ES2721513T3 (es) 2009-05-05 2010-05-04 Método para tratar vejigas hiperactivas y un dispositivo para el almacenamiento y la administración de composiciones tópicas de oxibutinina
ES10772664.8T Active ES2650611T3 (es) 2009-05-05 2010-05-04 Un método para tratar las vejigas hiperactivas y un dispositivo para la conservación y administración de composiciones tópicas de oxibutinina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES10772664.8T Active ES2650611T3 (es) 2009-05-05 2010-05-04 Un método para tratar las vejigas hiperactivas y un dispositivo para la conservación y administración de composiciones tópicas de oxibutinina

Country Status (14)

Country Link
US (4) US8920392B2 (es)
EP (2) EP2427172B1 (es)
JP (2) JP5485377B2 (es)
KR (1) KR20120030078A (es)
CN (1) CN102421411A (es)
AU (1) AU2010246103B2 (es)
BR (1) BRPI1015542B1 (es)
CA (2) CA2821174C (es)
DE (1) DE10772664T8 (es)
ES (2) ES2721513T3 (es)
MX (4) MX2011011642A (es)
RU (1) RU2011144397A (es)
WO (1) WO2010129498A2 (es)
ZA (1) ZA201108213B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11021300B2 (en) * 2019-10-16 2021-06-01 Sonoco Development, Inc. Flexible packaging with internal release
EP4185310A1 (en) * 2020-07-23 2023-05-31 Kimberly-Clark Worldwide, Inc. Method for modulating the bladder microbiome to improve bladder health
FR3132826A1 (fr) * 2022-02-24 2023-08-25 L'oreal Contenant de produit cosmétique fluide formant recharge pour un flacon principal

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3124825A (en) * 1964-03-17 Iovenko
US1908164A (en) * 1931-05-12 1933-05-09 William Wharton Jr & Company I Method of supplying carbon dioxide for aiding the growth of plants
GB515876A (en) 1937-10-05 1939-12-15 Leroy Lincoln Salfisberg Improvements relating to packages
US2954116A (en) * 1957-05-06 1960-09-27 Johnson & Johnson Rupturable seal package with sterilized moist contents
US2998880A (en) * 1958-06-19 1961-09-05 Bard Parker Company Inc Sterile surgical instrument and assembly
US3152515A (en) * 1959-02-04 1964-10-13 Polaroid Corp Liquid-carrying containers
US3057467A (en) * 1959-11-18 1962-10-09 Colgate Palmolive Co Package for treating agents and disposable applicator forming a part thereof
US3186869A (en) * 1961-02-23 1965-06-01 Friedman Jack Coated film for laundry package
US3152694A (en) * 1962-02-05 1964-10-13 Johnson & Johnson Article and method of manufacture
US3217871A (en) * 1963-05-06 1965-11-16 Acme Backing Corp Peelable seal package
US3426102A (en) 1965-08-18 1969-02-04 Standard Oil Co Polymerizates of olefinic nitriles and diene-nitrile rubbers
US3403776A (en) * 1967-03-21 1968-10-01 Johnson & Johnson Sterile surgical package
US3478868A (en) * 1967-09-01 1969-11-18 Interstate Folding Box Co Sterilizable containers
US3552638A (en) * 1968-08-14 1971-01-05 Nat Distillers Chem Corp Peel-open thermoplastic package for sterilized articles
US3563371A (en) * 1969-06-12 1971-02-16 W S Kirkpatrick & Co Inc Wet towel package
US3616898A (en) * 1969-09-08 1971-11-02 Abbott Lab Peelable seal package
US3847280A (en) * 1970-10-05 1974-11-12 Johnson & Johnson Sterile package for clinical thermometers and the like and method of making it
US3708106A (en) * 1971-05-17 1973-01-02 Ppg Industries Inc Bag structure and method of producing
US3995739A (en) * 1972-11-01 1976-12-07 Acme Backing Corporation Peelable, autoclavable packaging
US3937396A (en) * 1974-01-18 1976-02-10 Schneider William S Valve for vented package
US3913789A (en) * 1974-02-13 1975-10-21 United States Banknote Corp Fluid container of the flexible wall capsule type
US3926311A (en) * 1974-08-22 1975-12-16 Vonco Products Inc Peel-seal containers
GB1508492A (en) 1976-04-22 1978-04-26 Bowater Packaging Ltd Pack
JPS54115997A (en) 1978-02-28 1979-09-08 Toppan Printing Co Ltd Food vessel
US4359506A (en) * 1979-03-15 1982-11-16 Sohio Tie layer for co-extruded acrylonitrile copolymers
US4279344A (en) * 1979-12-26 1981-07-21 Reynolds Metals Company Heat-sealable and peelable laminated packaging construction
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
GB2086833B (en) * 1980-11-11 1985-01-03 Grace W R & Co Flexible easy-open package
US4552269A (en) * 1983-12-07 1985-11-12 Chang Sung Chol Resealable sealing device
US4656068A (en) * 1983-12-23 1987-04-07 Plicon Corporation Pellable seal package
ATE67739T1 (de) 1984-01-23 1991-10-15 Thomas C Laipply Alkoholwischer und verfahren.
JPS60189438A (ja) * 1984-03-09 1985-09-26 富士写真フイルム株式会社 写真感光材料包装用フイルム
US4784857A (en) * 1986-06-03 1988-11-15 Smith And Nephew Associated Companies Plc Drug delivery device, its preparation and use
US4964515A (en) * 1987-02-02 1990-10-23 Heyden Eugene L Bag construction including easy-opening provision
US4983395A (en) 1987-11-12 1991-01-08 Theratech Inc. Device for administering an active agent to the skin or mucosa
US5004610A (en) * 1988-06-14 1991-04-02 Alza Corporation Subsaturated nicotine transdermal therapeutic system
US5251982A (en) * 1988-07-08 1993-10-12 Ab Tetra Pak Discharging device for a packaging container
US5266371A (en) * 1988-08-11 1993-11-30 Nitto Denko Corporation Adhesive dressing sheet
WO1990005683A1 (en) 1988-11-24 1990-05-31 Leifron Pty Ltd Device for storing and applying substances to surfaces
US4998621A (en) * 1989-08-11 1991-03-12 Frank Meehan Package for a liquid sample and an associated method for packaging a liquid sample
US5077104A (en) * 1989-12-21 1991-12-31 Alza Corporation Nicotine packaging materials
US5167242A (en) * 1990-06-08 1992-12-01 Kabi Pharmacia Aktiebolaq Nicotine-impermeable container and method of fabricating the same
US5131760A (en) * 1990-07-03 1992-07-21 Farmer Bert E Packaging device
US5164190A (en) * 1990-12-11 1992-11-17 Theratech, Inc. Subsaturated transdermal drug delivery device exhibiting enhanced drug flux
US5227169A (en) * 1991-05-17 1993-07-13 Theratech, Inc. Sorbitan esters as skin permeation enhancers
DK123591A (da) 1991-06-25 1992-12-26 Schur Int As Brdr Genlukkelig salgsforpakning, f.eks. til skivepaalaeg
ES2114569T3 (es) 1991-10-16 1998-06-01 Richardson Vicks Inc Sistema mejorado de penetracion en la piel para la administracion topica mejorada de farmacos.
US6010715A (en) * 1992-04-01 2000-01-04 Bertek, Inc. Transdermal patch incorporating a polymer film incorporated with an active agent
US5900250A (en) * 1992-05-13 1999-05-04 Alza Corporation Monoglyceride/lactate ester permeation enhancer for oxybutnin
US5181610A (en) * 1992-05-15 1993-01-26 International Paper Company Flexible container with nonstick interior
US5253754A (en) * 1992-08-14 1993-10-19 American Fluoroseal Corporation Peel package and method of packaging organs
US5254109A (en) * 1992-12-07 1993-10-19 Creative Products Resource Associates, Ltd. Separately packaged applicator pads for topical delivery of incompatable drugs
US5341922A (en) * 1993-02-24 1994-08-30 Ethicon, Inc. Peelable foil suture packaging
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
CA2165802A1 (en) 1993-09-29 1995-04-06 Eun Soo Lee Monoglyceride/lactate ester permeation enhancer for oxybutynin
US5635203A (en) 1994-09-29 1997-06-03 Alza Corporation Transdermal device having decreased delamination
GB9425783D0 (en) * 1994-12-21 1995-02-22 Ethical Pharma Ltd Packaging of patches
WO1996019205A1 (en) 1994-12-21 1996-06-27 Theratech, Inc. Transdermal delivery system with adhesive overlay and peel seal disc
US5807568A (en) 1994-12-27 1998-09-15 Mcneil-Ppc, Inc. Enhanced delivery of topical compositions containing flurbiprofen
US5677346A (en) 1995-01-31 1997-10-14 Sepracor, Inc. Treating urinary incontinence using (S)-desethyloxybutynin
US5601839A (en) * 1995-04-26 1997-02-11 Theratech, Inc. Triacetin as a penetration enhancer for transdermal delivery of a basic drug
US5674895A (en) 1995-05-22 1997-10-07 Alza Corporation Dosage form comprising oxybutynin
US5912268A (en) 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
US6262115B1 (en) 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5846558A (en) * 1996-03-19 1998-12-08 Minnesota Mining And Manufacturing Company Ionically conductive adhesives prepared from zwitterionic materials and medical devices using such adhesives
US6326069B1 (en) * 1997-06-13 2001-12-04 Arcade, Inc. Fluid sampler pouch with internal supportive structure
US5948433A (en) * 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
DE69833000T2 (de) 1997-09-26 2006-09-07 Noven Pharmaceuticals, Inc., Miami Bio-klebemittelzusammensetzungen
US6660295B2 (en) * 1997-09-30 2003-12-09 Alza Corporation Transdermal drug delivery device package with improved drug stability
CA2275539A1 (en) * 1997-10-28 1999-05-06 Bando Chemical Industries, Ltd. A transdermal patch and a method for manufacture of a substrate sheet therefor
US5932552A (en) * 1997-11-26 1999-08-03 Keraplast Technologies Ltd. Keratin-based hydrogel for biomedical applications and method of production
US6059112A (en) * 1998-10-27 2000-05-09 Oliver Products Company Peel package
US6129929A (en) * 1998-10-30 2000-10-10 Noven Pharmaceuticals, Inc. Patch applicator
US6159497A (en) * 1998-10-30 2000-12-12 Noven Pharmaceuticals, Inc. Patch applicator
US6287652B2 (en) * 1998-12-09 2001-09-11 Color Prelude, Inc. Fluid product sampler package with clear moisture vapor barrier film
US6468516B1 (en) 1999-03-19 2002-10-22 Warner-Lambert Company Composition and manufacture of topical pharmaceutical and cosmetic semi-solid post-foaming dosage forms in a pouch
CA2384679A1 (en) * 1999-09-08 2001-03-15 Srinivasan Venkateshwaran Using quaternary ammonium salts for transdermal drug delivery
US6547468B2 (en) * 2001-06-22 2003-04-15 The Procter & Gamble Company Dosing reservoir
US6974588B1 (en) * 1999-12-07 2005-12-13 Elan Pharma International Limited Transdermal patch for delivering volatile liquid drugs
US6905016B2 (en) * 2000-03-14 2005-06-14 Noven Pharmaceuticals, Inc. Packaging system for transdermal drug delivery systems
CN101305994A (zh) * 2000-04-26 2008-11-19 沃特森药物公司 最小化与奥昔布宁疗法有关的副作用
US20030124177A1 (en) 2000-04-26 2003-07-03 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US7029694B2 (en) * 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
JP5684964B2 (ja) 2000-06-07 2015-03-18 ワトソン ファーマシューティカルズ， インコーポレイテッド （ｒ）−オキシブチニンおよび（ｒ）−デスエチルオキシブチニンによる平滑筋機能亢進の処置
IL158551A0 (en) 2001-04-23 2004-05-12 Noven Pharma Packaging system for transdermal drug delivery systems
US7194483B1 (en) 2001-05-07 2007-03-20 Intelligenxia, Inc. Method, system, and computer program product for concept-based multi-dimensional analysis of unstructured information
US7921999B1 (en) * 2001-12-20 2011-04-12 Watson Laboratories, Inc. Peelable pouch for transdermal patch and method for packaging
MXPA04007657A (es) 2002-02-08 2004-11-10 Procter & Gamble Sachet a prueba de ninos.
US6676961B1 (en) * 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US20040131805A1 (en) * 2002-06-20 2004-07-08 Merical Rick L. Films having a desiccant material incorporated therein and methods of use and manufacture
TW200512013A (en) * 2003-09-18 2005-04-01 Orient Europharma Co Ltd Gel formulation of oxybutynin hydrochloride
US7425340B2 (en) * 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
US7565828B2 (en) 2005-06-10 2009-07-28 Donbar Industries, Inc. Systems and methods for testing packaging
US8124096B2 (en) 2006-07-31 2012-02-28 3M Innovative Properties Company Immune response modifier compositions and methods
US20080226698A1 (en) * 2007-03-16 2008-09-18 Mylan Technologies, Inc. Amorphous drug transdermal systems, manufacturing methods, and stabilization
US8750954B2 (en) * 2008-03-31 2014-06-10 Covidien Lp Medical monitoring patch device and methods

Also Published As

Publication number Publication date
EP3287122B1 (en) 2019-04-17
MX367923B (es) 2019-09-12
CA2760867C (en) 2013-09-24
MX338166B (es) 2016-04-06
CA2821174C (en) 2016-04-05
RU2011144397A (ru) 2013-06-10
EP2427172A2 (en) 2012-03-14
US20200000760A1 (en) 2020-01-02
EP2427172B1 (en) 2017-11-01
EP3287122A1 (en) 2018-02-28
AU2010246103A1 (en) 2011-11-24
JP5485377B2 (ja) 2014-05-07
MX2011011642A (es) 2012-02-21
WO2010129498A3 (en) 2011-03-03
CA2821174A1 (en) 2010-11-11
JP2012526124A (ja) 2012-10-25
CN102421411A (zh) 2012-04-18
ES2650611T3 (es) 2018-01-19
BRPI1015542B1 (pt) 2022-05-10
JP2014144957A (ja) 2014-08-14
US8920392B2 (en) 2014-12-30
JP5795817B2 (ja) 2015-10-14
US20100286630A1 (en) 2010-11-11
CA2760867A1 (en) 2010-11-11
BRPI1015542A2 (pt) 2016-04-26
MX2019011031A (es) 2020-08-03
EP2427172A4 (en) 2014-02-19
US20140046275A1 (en) 2014-02-13
US20160128963A1 (en) 2016-05-12
US10449173B2 (en) 2019-10-22
AU2010246103B2 (en) 2013-03-21
WO2010129498A2 (en) 2010-11-11
ZA201108213B (en) 2013-04-24
KR20120030078A (ko) 2012-03-27
US9259388B2 (en) 2016-02-16
DE10772664T8 (de) 2013-04-25
DE10772664T1 (de) 2012-09-27

Similar Documents

Publication Publication Date Title
ES2494665T3 (es) Composición adhesiva mejorada
ES2487496T3 (es) Agente para aliviar el síndrome metabólico
CL2013002148A1 (es) Composición farmacéutica vaginal sólida efervescente que comprende un sistema ácido-base, una mezcla de celulosa microcristalina y arabinogalactano y al menos una cepa bacteriana probiótica; y su uso para el tratamiento de infecciones vaginales tales como vaginitis, candidiasis, gonorrea y úlcera venérea.
AR048017A1 (es) Composicion y metodo para aumentar la biodisponibilidad
AR087823A1 (es) Agentes de reticulacion multifuncionales de acido boronico y metodos asociados
CL2013003163A1 (es) Composición transdermica de ibuprofeno, util en el tratamiento del dolor o la inflamacion.
ES2721513T3 (es) Método para tratar vejigas hiperactivas y un dispositivo para el almacenamiento y la administración de composiciones tópicas de oxibutinina
MX352187B (es) Composición novedosa de hidrogel transdérmico de dexibuprofeno.
AR032200A1 (es) Productos antitranspirantes
UY33674A (es) Composiciones de recubrimiento con propiedades anticorrosivas
MX2019015396A (es) El uso de amisulpride como un anti-emetico.
ATE544517T1 (de) Regeneration eines mit hexachlorostannat beladenen anionenaustauschers
ES2623025T3 (es) Comprimido de desintegración oral que contiene acarbosa
AR070850A1 (es) Dispositivo para mejorar un metodo de voladura
RS53531B1 (en) BRIMONIDINE GEL COMPOSITION
US9884980B2 (en) PVC self-adhesive floorboard with water-resistant glue
TR201909029T4 (tr) Rifaksimin alfa içeren saklanmaya yönelik kararlı bileşimler.
PE20131337A1 (es) Composicion anestesica nanoparticulada para la administracion topica
ES2895772T1 (es) Solución de bortezomib lista para usar
MX2016003236A (es) Peliculas dispersables para envasar formulaciones de alto contenido de agua.
CN204625104U (zh) 防脱型叉车搬运装置
US20070134311A1 (en) External preparation
CL2008000570A1 (es) Metodo de conservacion de una composicion alimenticia, que comprende mezclar dicha composicion que contiene un polimero anionico con 20 a 200 ppm de un conservante cationico saturado con una carga total positiva en la ultima etapa de la mezcla y agregar opcionalmente 0,015 a 0,5% de un segundo preservante.
RU127046U1 (ru) Устройство для хранения труб
CN209990049U (zh) 一种lvt饰面的玻镁板