ES2687983T3 - Moduladores de la ruta del complemento y usos de los mismos - Google Patents
Moduladores de la ruta del complemento y usos de los mismos Download PDFInfo
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- ES2687983T3 ES2687983T3 ES13765778.9T ES13765778T ES2687983T3 ES 2687983 T3 ES2687983 T3 ES 2687983T3 ES 13765778 T ES13765778 T ES 13765778T ES 2687983 T3 ES2687983 T3 ES 2687983T3
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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| AR105808A1 (es) | 2015-08-26 | 2017-11-08 | Achillion Pharmaceuticals Inc | Compuestos de amida para el tratamiento de trastornos médicos |
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| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
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| WO2017035351A1 (en) * | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of medical disorders |
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| CA3053818A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders |
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| EP3841086B1 (en) | 2018-08-20 | 2025-04-23 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
| WO2020051538A1 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Morphic forms of complement factor d inhibitors |
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| KR20230009431A (ko) | 2020-05-12 | 2023-01-17 | 알렉시온 파마슈티칼스, 인코포레이티드 | 발작성 야간 혈색소뇨증의 치료를 위한 보체 인자 d 저해제를 단독으로 또는 항-c5 항체와 조합한 용도 |
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- 2013-06-27 EA EA201590200A patent/EA201590200A1/ru unknown
- 2013-06-27 CA CA2882724A patent/CA2882724A1/en not_active Abandoned
- 2013-06-27 ES ES13765778.9T patent/ES2687983T3/es active Active
- 2013-06-27 EP EP13765778.9A patent/EP2872503B1/en not_active Not-in-force
- 2013-06-27 AU AU2013288319A patent/AU2013288319A1/en not_active Abandoned
- 2013-06-27 JP JP2015521093A patent/JP6238980B2/ja not_active Expired - Fee Related
- 2013-06-27 IN IN185DEN2015 patent/IN2015DN00185A/en unknown
- 2013-06-27 CN CN201380046562.3A patent/CN104684910B/zh not_active Expired - Fee Related
- 2013-06-27 MX MX2015000537A patent/MX2015000537A/es unknown
- 2013-06-27 KR KR20157003423A patent/KR20150036481A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015000537A (es) | 2015-05-11 |
| US9550755B2 (en) | 2017-01-24 |
| EP2872503B1 (en) | 2018-06-20 |
| EA201590200A1 (ru) | 2015-08-31 |
| AU2013288319A1 (en) | 2015-02-05 |
| CN104684910B (zh) | 2016-10-12 |
| CN104684910A (zh) | 2015-06-03 |
| JP2015522062A (ja) | 2015-08-03 |
| IN2015DN00185A (enExample) | 2015-06-12 |
| WO2014009833A2 (en) | 2014-01-16 |
| US20150148374A1 (en) | 2015-05-28 |
| CA2882724A1 (en) | 2014-01-16 |
| BR112015000578A2 (pt) | 2017-06-27 |
| EP2872503A2 (en) | 2015-05-20 |
| JP6238980B2 (ja) | 2017-11-29 |
| KR20150036481A (ko) | 2015-04-07 |
| WO2014009833A3 (en) | 2014-03-20 |
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