ES2684512T3 - Método para predecir el riesgo de un sujeto de contraer la diabetes mellitus y/o el síndrome metabólico o para diagnosticar el síndrome metabólico en un sujeto - Google Patents
Método para predecir el riesgo de un sujeto de contraer la diabetes mellitus y/o el síndrome metabólico o para diagnosticar el síndrome metabólico en un sujeto Download PDFInfo
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- ES2684512T3 ES2684512T3 ES13708803.5T ES13708803T ES2684512T3 ES 2684512 T3 ES2684512 T3 ES 2684512T3 ES 13708803 T ES13708803 T ES 13708803T ES 2684512 T3 ES2684512 T3 ES 2684512T3
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- proneurotensin
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- VUFNRPJNRFOTGK-UHFFFAOYSA-M sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate Chemical compound [Na+].O=C1C(S(=O)(=O)[O-])CC(=O)N1OC(=O)C1CCC(CN2C(C=CC2=O)=O)CC1 VUFNRPJNRFOTGK-UHFFFAOYSA-M 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000004988 splenocyte Anatomy 0.000 description 1
- 108010013645 tetranectin Proteins 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 229960003726 vasopressin Drugs 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
- G01N2333/4706—Regulators; Modulating activity stimulating, promoting or activating activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261608350P | 2012-03-08 | 2012-03-08 | |
| EP12158680 | 2012-03-08 | ||
| EP12158680 | 2012-03-08 | ||
| US201261608350P | 2012-03-08 | ||
| EP12165062 | 2012-04-20 | ||
| EP12165062 | 2012-04-20 | ||
| PCT/EP2013/054801 WO2013132090A1 (en) | 2012-03-08 | 2013-03-08 | A method for predicting the risk of a subject for contracting diabetes mellitus and/or metabolic syndrome or for diagnosing metabolic syndrome in a subject |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2684512T3 true ES2684512T3 (es) | 2018-10-03 |
Family
ID=49115970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13708803.5T Active ES2684512T3 (es) | 2012-03-08 | 2013-03-08 | Método para predecir el riesgo de un sujeto de contraer la diabetes mellitus y/o el síndrome metabólico o para diagnosticar el síndrome metabólico en un sujeto |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10520512B2 (https=) |
| EP (1) | EP2823316B1 (https=) |
| JP (1) | JP6262669B2 (https=) |
| CN (1) | CN103308670B (https=) |
| ES (1) | ES2684512T3 (https=) |
| IN (1) | IN2014MN01937A (https=) |
| RU (1) | RU2685713C2 (https=) |
| TR (1) | TR201811201T4 (https=) |
| WO (1) | WO2013132090A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103308689B (zh) * | 2012-03-08 | 2017-04-12 | 思芬构技术有限公司 | 用于预测雌性对象中患上癌症的风险或诊断癌症的方法 |
| EP3002589A1 (en) * | 2014-10-01 | 2016-04-06 | sphingotec GmbH | A method for stratifying a female subject for hormone replacement therapy |
| ES2781084T3 (es) * | 2015-02-27 | 2020-08-28 | Sphingotec Gmbh | Un método para predecir el riesgo de obesidad en un sujeto |
| US10473670B2 (en) | 2016-02-25 | 2019-11-12 | University Of Kentucky Research Foundation | Method of predicting obesity comprising measuring neurotensin |
| WO2022203533A1 (ru) * | 2021-03-25 | 2022-09-29 | Владимир Валерьевич ВОЛОБУЕВ | Способ оценки предрасположенности к различным формам сахарного диабета 2го типа |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8709871D0 (en) * | 1987-04-27 | 1987-06-03 | Turner R C | Peptides |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5430047A (en) * | 1994-04-07 | 1995-07-04 | Warner-Lambert Company | Neurotensin antagonists |
| WO1995033474A1 (en) * | 1994-06-03 | 1995-12-14 | Tsumura & Co. | Medicinal composition |
| JP4394279B2 (ja) * | 1998-03-09 | 2010-01-06 | ジーランド ファーマ アクティーゼルスカブ | 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体 |
| US6248527B1 (en) * | 1998-10-21 | 2001-06-19 | Millennium Pharmaceuticals, Inc. | Method of detecting risk of type II diabetes based on mutations found in carboxypeptidase E |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| IL142707A0 (en) * | 2000-04-27 | 2002-03-10 | Pfizer Prod Inc | Methods of treating obesity using a neurotensin receptor ligand |
| US7271153B2 (en) * | 2001-06-20 | 2007-09-18 | Kissei Pharmaceutical Co., Ltd. | Nitrogenous heterocyclic derivatives, medicinal compositions containing the same, medicinal uses thereof, and intermediates therefor |
| RU2004109222A (ru) | 2001-08-30 | 2005-10-20 | Байорексис Фармасьютикал Корпорейшн (Us) | Слитые белки модифицированного трансферрина |
| WO2003103475A2 (en) | 2002-06-07 | 2003-12-18 | Dyax Corp. | Prevention and reduction of blood loss |
| WO2005040229A2 (en) | 2003-10-24 | 2005-05-06 | Avidia, Inc. | Ldl receptor class a and egf domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| US8278262B2 (en) | 2004-09-21 | 2012-10-02 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| DE102005003687A1 (de) * | 2005-01-26 | 2006-07-27 | Sphingo Tec Gmbh | Immunoassay zur Bestimmung der Freisetzung von Neurotensin in die Zirkulation |
| WO2006110082A1 (en) * | 2005-04-11 | 2006-10-19 | Astrazeneca Ab | A method and a kit for diagnosing type 2 diabetes, metabolic syndrome, sub clinical atherosclerosis, myocardial infarct, stroke or clinical manifestations of diabetes. |
| US8119358B2 (en) * | 2005-10-11 | 2012-02-21 | Tethys Bioscience, Inc. | Diabetes-related biomarkers and methods of use thereof |
| DK2231860T3 (da) | 2007-12-19 | 2011-12-05 | Affibody Ab | Polypeptid afledt protein A og i stand til at binde PDGF |
| EP3785735A1 (en) | 2008-11-03 | 2021-03-03 | Molecular Partners AG | Binding proteins inhibiting the vegf-a receptor interaction |
| CA2745524C (en) * | 2008-12-05 | 2020-06-09 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| EP2374003B1 (en) | 2009-01-07 | 2015-03-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment, the prognostic assessment and the detection of breast cancer |
| MX2012002428A (es) | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| US9217747B2 (en) * | 2009-10-29 | 2015-12-22 | Health Diagnostic Laboratory, Inc. | Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes |
| AU2010332932B2 (en) | 2009-12-14 | 2013-01-17 | Navigo Proteins Gmbh | Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin |
| UA58612U (uk) * | 2010-06-04 | 2011-04-26 | Высшее Государственное Учебное Заведение «Украинская Медицинская Стоматологическая Академия» | Спосіб діагностики інсулінорезистентності у хворих на метаболічний синдром та цукровий діабет 2 типу |
| RU2569745C2 (ru) | 2010-06-08 | 2015-11-27 | Пиерис АГ | Мутеины липокалина слезы, связывающие альфа il-4 r |
| ES2781084T3 (es) * | 2015-02-27 | 2020-08-28 | Sphingotec Gmbh | Un método para predecir el riesgo de obesidad en un sujeto |
-
2012
- 2012-10-08 CN CN201210509621.3A patent/CN103308670B/zh active Active
-
2013
- 2013-03-08 IN IN1937MUN2014 patent/IN2014MN01937A/en unknown
- 2013-03-08 WO PCT/EP2013/054801 patent/WO2013132090A1/en not_active Ceased
- 2013-03-08 US US14/383,422 patent/US10520512B2/en active Active
- 2013-03-08 ES ES13708803.5T patent/ES2684512T3/es active Active
- 2013-03-08 JP JP2014560405A patent/JP6262669B2/ja active Active
- 2013-03-08 RU RU2014140427A patent/RU2685713C2/ru active
- 2013-03-08 EP EP13708803.5A patent/EP2823316B1/en active Active
- 2013-03-08 TR TR2018/11201T patent/TR201811201T4/tr unknown
-
2019
- 2019-12-18 US US16/719,507 patent/US20200326350A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20150056203A1 (en) | 2015-02-26 |
| JP2015512048A (ja) | 2015-04-23 |
| EP2823316B1 (en) | 2018-05-23 |
| CN103308670A (zh) | 2013-09-18 |
| US10520512B2 (en) | 2019-12-31 |
| IN2014MN01937A (https=) | 2015-07-10 |
| EP2823316A1 (en) | 2015-01-14 |
| RU2685713C2 (ru) | 2019-04-23 |
| JP6262669B2 (ja) | 2018-01-17 |
| US20200326350A1 (en) | 2020-10-15 |
| TR201811201T4 (tr) | 2018-09-21 |
| RU2014140427A (ru) | 2016-04-27 |
| CN103308670B (zh) | 2017-06-09 |
| WO2013132090A1 (en) | 2013-09-12 |
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