ES2671402T3 - Moduladores de pirrolidina GPR40 para el tratamiento de enfermedades tales como diabetes - Google Patents
Moduladores de pirrolidina GPR40 para el tratamiento de enfermedades tales como diabetes Download PDFInfo
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- ES2671402T3 ES2671402T3 ES15723096.2T ES15723096T ES2671402T3 ES 2671402 T3 ES2671402 T3 ES 2671402T3 ES 15723096 T ES15723096 T ES 15723096T ES 2671402 T3 ES2671402 T3 ES 2671402T3
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461989560P | 2014-05-07 | 2014-05-07 | |
| US201461989560P | 2014-05-07 | ||
| PCT/US2015/029422 WO2015171733A1 (en) | 2014-05-07 | 2015-05-06 | Pyrrolidine gpr40 modulators for the treatment of diseases such as diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2671402T3 true ES2671402T3 (es) | 2018-06-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15723096.2T Active ES2671402T3 (es) | 2014-05-07 | 2015-05-06 | Moduladores de pirrolidina GPR40 para el tratamiento de enfermedades tales como diabetes |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10017497B2 (Direct) |
| EP (1) | EP3140297B1 (Direct) |
| JP (1) | JP6488320B2 (Direct) |
| KR (1) | KR20170002543A (Direct) |
| CN (1) | CN106458987B (Direct) |
| AU (1) | AU2015256038B2 (Direct) |
| BR (1) | BR112016025188A2 (Direct) |
| CA (1) | CA2948175A1 (Direct) |
| EA (1) | EA032290B1 (Direct) |
| ES (1) | ES2671402T3 (Direct) |
| IL (1) | IL248670B (Direct) |
| MX (1) | MX2016014118A (Direct) |
| SG (1) | SG11201609167RA (Direct) |
| WO (1) | WO2015171733A1 (Direct) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| KR102708681B1 (ko) | 2018-02-13 | 2024-09-26 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| EP4600247A3 (en) | 2018-04-19 | 2025-11-19 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| UA126421C2 (uk) | 2018-07-13 | 2022-09-28 | Гіліад Сайєнсіз, Інк. | Інгібітори pd-1/pd-l1 |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5614492A (en) | 1986-05-05 | 1997-03-25 | The General Hospital Corporation | Insulinotropic hormone GLP-1 (7-36) and uses thereof |
| US6995183B2 (en) | 2003-08-01 | 2006-02-07 | Bristol Myers Squibb Company | Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods |
| CN102639495A (zh) * | 2009-10-06 | 2012-08-15 | 百时美施贵宝公司 | 吡咯烷gpr40调节剂 |
| JP5864177B2 (ja) | 2011-09-15 | 2016-02-17 | 船井電機株式会社 | プロジェクタおよびプロジェクタシステム |
| KR20150082618A (ko) * | 2012-11-16 | 2015-07-15 | 브리스톨-마이어스 스큅 컴퍼니 | 디히드로피라졸 gpr40 조절제 |
| US9656963B2 (en) * | 2012-11-16 | 2017-05-23 | Bristol-Myers Squibb Company | Dihydropyrazole GPR40 modulators |
| HUE032401T2 (en) * | 2012-11-16 | 2017-09-28 | Bristol Myers Squibb Co | Dihydropyrazole GPR40 modulators |
| BR112015010649A2 (pt) * | 2012-11-16 | 2017-07-11 | Bristol Myers Squibb Co | moduladores de gpr40 à base de pirrolidina |
| TR201809633T4 (tr) * | 2014-05-07 | 2018-07-23 | Bristol Myers Squibb Co | Diyabet gibi hastalıkların tedavisine yönelik pirolidin GPR40 modülatörleri. |
-
2015
- 2015-05-06 KR KR1020167033864A patent/KR20170002543A/ko not_active Withdrawn
- 2015-05-06 SG SG11201609167RA patent/SG11201609167RA/en unknown
- 2015-05-06 ES ES15723096.2T patent/ES2671402T3/es active Active
- 2015-05-06 US US15/308,428 patent/US10017497B2/en active Active
- 2015-05-06 WO PCT/US2015/029422 patent/WO2015171733A1/en not_active Ceased
- 2015-05-06 EP EP15723096.2A patent/EP3140297B1/en not_active Not-in-force
- 2015-05-06 AU AU2015256038A patent/AU2015256038B2/en not_active Ceased
- 2015-05-06 CN CN201580023783.8A patent/CN106458987B/zh not_active Expired - Fee Related
- 2015-05-06 BR BR112016025188A patent/BR112016025188A2/pt not_active Application Discontinuation
- 2015-05-06 EA EA201692216A patent/EA032290B1/ru not_active IP Right Cessation
- 2015-05-06 CA CA2948175A patent/CA2948175A1/en not_active Abandoned
- 2015-05-06 MX MX2016014118A patent/MX2016014118A/es unknown
- 2015-05-06 JP JP2016566729A patent/JP6488320B2/ja not_active Expired - Fee Related
-
2016
- 2016-11-01 IL IL248670A patent/IL248670B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP3140297A1 (en) | 2017-03-15 |
| EA032290B1 (ru) | 2019-05-31 |
| CA2948175A1 (en) | 2015-11-12 |
| CN106458987A (zh) | 2017-02-22 |
| AU2015256038A1 (en) | 2016-12-22 |
| IL248670A0 (en) | 2017-01-31 |
| KR20170002543A (ko) | 2017-01-06 |
| IL248670B (en) | 2019-09-26 |
| SG11201609167RA (en) | 2016-12-29 |
| EP3140297B1 (en) | 2018-04-11 |
| US20170217930A1 (en) | 2017-08-03 |
| JP2017514865A (ja) | 2017-06-08 |
| EA201692216A1 (ru) | 2017-04-28 |
| AU2015256038B2 (en) | 2019-07-11 |
| BR112016025188A2 (pt) | 2017-08-15 |
| WO2015171733A1 (en) | 2015-11-12 |
| MX2016014118A (es) | 2017-02-09 |
| US10017497B2 (en) | 2018-07-10 |
| JP6488320B2 (ja) | 2019-03-20 |
| CN106458987B (zh) | 2019-09-24 |
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