ES2665917T3 - Endoxifeno para su uso en el tratamiento del cáncer - Google Patents
Endoxifeno para su uso en el tratamiento del cáncer Download PDFInfo
- Publication number
- ES2665917T3 ES2665917T3 ES07871563.8T ES07871563T ES2665917T3 ES 2665917 T3 ES2665917 T3 ES 2665917T3 ES 07871563 T ES07871563 T ES 07871563T ES 2665917 T3 ES2665917 T3 ES 2665917T3
- Authority
- ES
- Spain
- Prior art keywords
- endoxifene
- cancer treatment
- endoxyphene
- cancer
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86042006P | 2006-11-21 | 2006-11-21 | |
| US860420P | 2006-11-21 | ||
| US86078806P | 2006-11-22 | 2006-11-22 | |
| US860788P | 2006-11-22 | ||
| PCT/US2007/085443 WO2008070463A2 (en) | 2006-11-21 | 2007-11-21 | Endoxifen methods and compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2665917T3 true ES2665917T3 (es) | 2018-04-30 |
Family
ID=39492975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07871563.8T Active ES2665917T3 (es) | 2006-11-21 | 2007-11-21 | Endoxifeno para su uso en el tratamiento del cáncer |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9333190B2 (OSRAM) |
| EP (1) | EP2101731B1 (OSRAM) |
| JP (1) | JP2010510327A (OSRAM) |
| CA (1) | CA2669913C (OSRAM) |
| DK (1) | DK2101731T3 (OSRAM) |
| ES (1) | ES2665917T3 (OSRAM) |
| HU (1) | HUE037109T2 (OSRAM) |
| IN (1) | IN2014MN00139A (OSRAM) |
| PL (1) | PL2101731T3 (OSRAM) |
| PT (1) | PT2101731T (OSRAM) |
| WO (1) | WO2008070463A2 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE037109T2 (hu) | 2006-11-21 | 2018-08-28 | Jina Pharmaceuticals Inc | Endoxifén rák kezelésében történõ alkalmazásra |
| US20090291134A1 (en) * | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| SI2373305T1 (sl) * | 2008-12-11 | 2017-09-29 | Besins Healthcare Luxembourg Sarl | Transdermalni farmacevtski sestavki, ki obsegajo serm |
| HRP20221355T1 (hr) | 2011-04-28 | 2022-12-23 | Oncopeptides Ab | Liofilizirani pripravak citotoksičnih dipeptida |
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| PL2928463T3 (pl) * | 2012-10-26 | 2020-06-01 | Oncopeptides Ab | Liofilizowane preparaty flufenamidu melfalanu |
| CN108024959A (zh) * | 2015-07-14 | 2018-05-11 | 阿托萨遗传学公司 | 用于治疗乳腺病症的经乳头方法和组合物 |
| DE102015222031A1 (de) | 2015-11-10 | 2017-05-11 | Robert Bosch Gesellschaft Für Medizinische Forschung Mbh | Synthese von (Z)-Endoxifenhydrochlorid |
| US20170304232A1 (en) * | 2016-04-20 | 2017-10-26 | Northwestern University | Endoxifen For Local Transdermal Therapy To The Breast |
| EP3681478B1 (en) * | 2017-09-11 | 2025-09-10 | Atossa Therapeutics, Inc. | Topical compositions and methods for treatment |
| TWI793165B (zh) | 2017-09-11 | 2023-02-21 | 美商阿托薩醫療公司 | 製造及使用因多昔芬(endoxifen)之方法 |
| WO2021003433A1 (en) * | 2019-07-03 | 2021-01-07 | Atossa Therapeutics, Inc. | Sustained release compositions of endoxifen |
| WO2021205402A1 (en) | 2020-04-10 | 2021-10-14 | Jina Pharmaceuticals, Inc. | Endoxifen for the treatment of bipolar i disorder |
| US12245997B2 (en) | 2020-04-10 | 2025-03-11 | Jina Pharmaceuticals, Inc. | Endoxifen for the treatment of bipolar I disorder |
| WO2022197988A1 (en) * | 2021-03-18 | 2022-09-22 | National Taiwan University | Lipid-based nanoparticle delivery system for hydrophilic charged compound |
| IL314075A (en) | 2022-01-12 | 2024-09-01 | Atossa Therapeutics Inc | Compositions of (Z)-endoxifen and methods for their enrichment |
| KR20250002604A (ko) * | 2022-04-26 | 2025-01-07 | 아토사 테라퓨틱스, 인크. | 고용량 엔독시펜 제제 및 사용 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2817157A1 (de) * | 1978-04-17 | 1979-10-25 | Schering Ag | Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie |
| ES2208687T3 (es) * | 1994-08-04 | 2004-06-16 | Elan Drug Delivery Limited | Sistema de administracion de sustancias solidas para la liberacion controlada de moleculas incorporadas en tales sustancias y procedimientos para la fabricacion de tales sistemas. |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| AU736301B2 (en) * | 1996-05-01 | 2001-07-26 | Imarx Therapeutics, Inc. | Methods for delivering compounds into a cell |
| US6090407A (en) * | 1997-09-23 | 2000-07-18 | Research Development Foundation | Small particle liposome aerosols for delivery of anti-cancer drugs |
| US7968532B2 (en) | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| PT2076244T (pt) | 2006-10-10 | 2017-03-09 | Jina Pharmaceuticals Inc | Sistemas aquosos para a preparação de compostos farmacêuticos à base de lípidos; composições, métodos e utilizações dos mesmos |
| WO2008048194A1 (en) | 2006-10-20 | 2008-04-24 | Yesilogluj Aysegul Yildiz | Use of the protein kinase c inhibitor tamoxifen for the treatment of bipolar disorder |
| EP2088865B1 (en) | 2006-11-06 | 2015-10-21 | Jina Pharmaceuticals Inc. | Guggulphospholipid methods and compositions |
| HUE037109T2 (hu) | 2006-11-21 | 2018-08-28 | Jina Pharmaceuticals Inc | Endoxifén rák kezelésében történõ alkalmazásra |
| US20090291134A1 (en) * | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| JP5720881B2 (ja) | 2011-01-31 | 2015-05-20 | 東芝ライテック株式会社 | Ｌｅｄランプ点灯装置および照明装置 |
-
2007
- 2007-11-21 HU HUE07871563A patent/HUE037109T2/hu unknown
- 2007-11-21 PL PL07871563T patent/PL2101731T3/pl unknown
- 2007-11-21 PT PT78715638T patent/PT2101731T/pt unknown
- 2007-11-21 WO PCT/US2007/085443 patent/WO2008070463A2/en not_active Ceased
- 2007-11-21 CA CA2669913A patent/CA2669913C/en active Active
- 2007-11-21 US US12/515,261 patent/US9333190B2/en active Active
- 2007-11-21 JP JP2009538518A patent/JP2010510327A/ja active Pending
- 2007-11-21 EP EP07871563.8A patent/EP2101731B1/en not_active Revoked
- 2007-11-21 IN IN139MUN2014 patent/IN2014MN00139A/en unknown
- 2007-11-21 DK DK07871563.8T patent/DK2101731T3/en active
- 2007-11-21 ES ES07871563.8T patent/ES2665917T3/es active Active
-
2016
- 2016-04-27 US US15/139,687 patent/US10376479B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2101731A2 (en) | 2009-09-23 |
| IN2014MN00139A (OSRAM) | 2015-06-19 |
| CA2669913A1 (en) | 2008-06-12 |
| US20100112041A1 (en) | 2010-05-06 |
| WO2008070463A9 (en) | 2008-09-18 |
| WO2008070463A3 (en) | 2008-11-06 |
| PL2101731T3 (pl) | 2018-07-31 |
| EP2101731A4 (en) | 2011-04-20 |
| US20160346230A1 (en) | 2016-12-01 |
| US10376479B2 (en) | 2019-08-13 |
| PT2101731T (pt) | 2018-04-18 |
| WO2008070463A2 (en) | 2008-06-12 |
| CA2669913C (en) | 2012-09-18 |
| HUE037109T2 (hu) | 2018-08-28 |
| JP2010510327A (ja) | 2010-04-02 |
| US9333190B2 (en) | 2016-05-10 |
| EP2101731B1 (en) | 2018-01-31 |
| DK2101731T3 (en) | 2018-04-16 |
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