ES2655688T3 - Composiciones terapéuticas para polineuropatía simétrica diabética - Google Patents
Composiciones terapéuticas para polineuropatía simétrica diabética Download PDFInfo
- Publication number
- ES2655688T3 ES2655688T3 ES11835385.3T ES11835385T ES2655688T3 ES 2655688 T3 ES2655688 T3 ES 2655688T3 ES 11835385 T ES11835385 T ES 11835385T ES 2655688 T3 ES2655688 T3 ES 2655688T3
- Authority
- ES
- Spain
- Prior art keywords
- approximately
- composition
- pirenzepine
- diabetic
- mice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40650210P | 2010-10-25 | 2010-10-25 | |
| US406502P | 2010-10-25 | ||
| US201161531803P | 2011-09-07 | 2011-09-07 | |
| US201161531803P | 2011-09-07 | ||
| PCT/CA2011/001186 WO2012055018A1 (en) | 2010-10-25 | 2011-10-24 | Therapeutic compositions for diabetic symmetrical polyneuropathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2655688T3 true ES2655688T3 (es) | 2018-02-21 |
Family
ID=45993001
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11835385.3T Active ES2655688T3 (es) | 2010-10-25 | 2011-10-24 | Composiciones terapéuticas para polineuropatía simétrica diabética |
| ES17206278T Active ES3016907T3 (en) | 2010-10-25 | 2011-10-24 | Therapeutic compositions for diabetic symmetrical polyneuropathy |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES17206278T Active ES3016907T3 (en) | 2010-10-25 | 2011-10-24 | Therapeutic compositions for diabetic symmetrical polyneuropathy |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10307428B2 (enExample) |
| EP (3) | EP4537829A3 (enExample) |
| CN (1) | CN103298473B (enExample) |
| CA (1) | CA2804797C (enExample) |
| DK (1) | DK2632468T3 (enExample) |
| ES (2) | ES2655688T3 (enExample) |
| HR (1) | HRP20250395T1 (enExample) |
| HU (1) | HUE070784T2 (enExample) |
| NO (1) | NO2632468T3 (enExample) |
| PL (2) | PL2632468T3 (enExample) |
| PT (1) | PT2632468T (enExample) |
| RS (1) | RS66691B1 (enExample) |
| WO (1) | WO2012055018A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3082845B1 (en) * | 2013-12-20 | 2021-02-17 | University Of Manitoba | Methods and compositions for treatment of peripheral neuropathies |
| US9743513B2 (en) | 2014-12-26 | 2017-08-22 | Industrial Technology Research Institute | Flexible electronic device |
| MX2021011607A (es) * | 2019-03-26 | 2021-12-10 | Winsantor Inc | Formulaciones topicas para el tratamiento de neuropatias perifericas. |
| CN121079085A (zh) * | 2023-03-16 | 2025-12-05 | 格劳科斯公司 | 眼科乳膏剂制剂及其用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6512010B1 (en) * | 1996-07-15 | 2003-01-28 | Alza Corporation | Formulations for the administration of fluoxetine |
| JP2002515514A (ja) * | 1998-05-21 | 2002-05-28 | アイシス・ファーマシューティカルス・インコーポレーテッド | オリゴヌクレオチドの局所送逹のための組成物及び方法 |
| US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
| MXPA03010655A (es) * | 2001-05-25 | 2007-06-22 | Valley Forge Pharmaceuticals I | Gel oft??lmico de pirenzepina. |
| WO2003026585A2 (en) * | 2001-09-26 | 2003-04-03 | Lukacsko Alison B | Compositions and methods for inhibiting eccrine perspiration in humans |
| WO2007025613A2 (en) * | 2005-07-15 | 2007-03-08 | Laboratorios Del Dr. Esteve, S.A. | Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain |
| KR20080071185A (ko) * | 2005-11-21 | 2008-08-01 | 쉐링-프라우 리미티드 | 부프레노르핀을 포함하는 약제학적 조성물 |
| US8748419B2 (en) * | 2006-06-16 | 2014-06-10 | Theracos, Inc. | Treating obesity with muscarinic receptor M1 antagonists |
| UA99259C2 (ru) * | 2006-06-16 | 2012-08-10 | Теракос, Инк. | Лечение ожирения антагонистами мускаринового рецептора м1 |
| US7893053B2 (en) | 2006-06-16 | 2011-02-22 | Theracos, Inc. | Treating psychological conditions using muscarinic receptor M1 antagonists |
| US20080255062A1 (en) * | 2007-02-13 | 2008-10-16 | University Of Manitoba | Axon regeneration from adult sensory neurons |
| CN101422610A (zh) * | 2007-12-04 | 2009-05-06 | 袁才蔚 | 一种化学药复合物制剂及其应用 |
-
2011
- 2011-10-24 US US13/877,619 patent/US10307428B2/en active Active
- 2011-10-24 DK DK11835385.3T patent/DK2632468T3/en active
- 2011-10-24 HR HRP20250395TT patent/HRP20250395T1/hr unknown
- 2011-10-24 RS RS20250342A patent/RS66691B1/sr unknown
- 2011-10-24 PL PL11835385T patent/PL2632468T3/pl unknown
- 2011-10-24 WO PCT/CA2011/001186 patent/WO2012055018A1/en not_active Ceased
- 2011-10-24 CN CN201180062520.XA patent/CN103298473B/zh active Active
- 2011-10-24 EP EP25150534.3A patent/EP4537829A3/en active Pending
- 2011-10-24 PT PT118353853T patent/PT2632468T/pt unknown
- 2011-10-24 CA CA2804797A patent/CA2804797C/en active Active
- 2011-10-24 NO NO11835385A patent/NO2632468T3/no unknown
- 2011-10-24 ES ES11835385.3T patent/ES2655688T3/es active Active
- 2011-10-24 ES ES17206278T patent/ES3016907T3/es active Active
- 2011-10-24 HU HUE17206278A patent/HUE070784T2/hu unknown
- 2011-10-24 EP EP17206278.8A patent/EP3363439B1/en active Active
- 2011-10-24 PL PL17206278.8T patent/PL3363439T3/pl unknown
- 2011-10-24 EP EP11835385.3A patent/EP2632468B1/en active Active
-
2018
- 2018-10-15 US US16/160,403 patent/US11925649B2/en active Active
-
2024
- 2024-02-08 US US18/437,093 patent/US20240180922A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20250395T1 (hr) | 2025-05-23 |
| CN103298473B (zh) | 2015-07-29 |
| EP2632468A4 (en) | 2014-08-27 |
| CN103298473A (zh) | 2013-09-11 |
| EP4537829A3 (en) | 2025-06-18 |
| HUE070784T2 (hu) | 2025-06-28 |
| EP2632468A1 (en) | 2013-09-04 |
| EP2632468B1 (en) | 2017-12-13 |
| WO2012055018A1 (en) | 2012-05-03 |
| DK2632468T3 (en) | 2018-02-12 |
| ES3016907T3 (en) | 2025-05-12 |
| EP3363439A3 (en) | 2018-12-05 |
| PL2632468T3 (pl) | 2018-04-30 |
| EP3363439A2 (en) | 2018-08-22 |
| CA2804797A1 (en) | 2012-05-03 |
| EP4537829A2 (en) | 2025-04-16 |
| PT2632468T (pt) | 2018-03-02 |
| RS66691B1 (sr) | 2025-05-30 |
| US10307428B2 (en) | 2019-06-04 |
| PL3363439T3 (pl) | 2025-09-22 |
| NO2632468T3 (enExample) | 2018-05-12 |
| US11925649B2 (en) | 2024-03-12 |
| US20190046540A1 (en) | 2019-02-14 |
| US20130267506A1 (en) | 2013-10-10 |
| US20240180922A1 (en) | 2024-06-06 |
| EP3363439B1 (en) | 2025-01-08 |
| CA2804797C (en) | 2014-12-23 |
| EP3363439C0 (en) | 2025-01-08 |
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