ES2646141T3 - Composiciones de poliláctido y usos de las mismas - Google Patents

Composiciones de poliláctido y usos de las mismas Download PDF

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Publication number
ES2646141T3
ES2646141T3 ES06809004.2T ES06809004T ES2646141T3 ES 2646141 T3 ES2646141 T3 ES 2646141T3 ES 06809004 T ES06809004 T ES 06809004T ES 2646141 T3 ES2646141 T3 ES 2646141T3
Authority
ES
Spain
Prior art keywords
pharmaceutical preparation
substituted
lactide
rop
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES06809004.2T
Other languages
English (en)
Spanish (es)
Inventor
Michael Moller
Thomas Trimaille
Robert Gurny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Geneve
Original Assignee
Universite de Geneve
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Geneve filed Critical Universite de Geneve
Application granted granted Critical
Publication of ES2646141T3 publication Critical patent/ES2646141T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
ES06809004.2T 2005-04-22 2006-04-21 Composiciones de poliláctido y usos de las mismas Expired - Lifetime ES2646141T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US67410305P 2005-04-22 2005-04-22
US674103P 2005-04-22
US75014105P 2005-12-14 2005-12-14
US750141P 2005-12-14
PCT/IB2006/002849 WO2007012979A2 (en) 2005-04-22 2006-04-21 Polylactide compositions and uses thereof

Publications (1)

Publication Number Publication Date
ES2646141T3 true ES2646141T3 (es) 2017-12-12

Family

ID=37603048

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06809004.2T Expired - Lifetime ES2646141T3 (es) 2005-04-22 2006-04-21 Composiciones de poliláctido y usos de las mismas

Country Status (9)

Country Link
US (5) US8466133B2 (https=)
EP (2) EP1883665B1 (https=)
JP (5) JP5749881B2 (https=)
CA (1) CA2605652C (https=)
DK (1) DK1883665T3 (https=)
ES (1) ES2646141T3 (https=)
PL (1) PL1883665T3 (https=)
PT (1) PT1883665T (https=)
WO (1) WO2007012979A2 (https=)

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AR092821A1 (es) * 2012-04-20 2015-05-06 Sucampo Ag Conjugado de derivado de acido graso-polimero
JP6422893B2 (ja) * 2013-02-08 2018-11-14 トタル リサーチ アンド テクノロジー フエリユイ 環状エステルおよび環状アミドの製造方法
US9080012B2 (en) * 2013-07-10 2015-07-14 Xerox Corporation One-pot, neat ring opening polymerization to prepare resin
US8975344B2 (en) * 2013-07-10 2015-03-10 Xerox Corporation Polyester/polycarbonate block copolymers via one-pot, neat ring opening polymerization
DE102013018193A1 (de) 2013-10-30 2015-05-13 Martin-Luther-Universität Halle-Wittenberg, Körperschaft des öffentlichen Rechts Injizierbare Depotformulierungen zur kontrollierten Wirkstofffreisetzung
CA2940955C (en) * 2014-02-26 2022-03-15 University Of Massachusetts Medical School Amphiphilic degradable polymers for immobilization and sustained delivery of biomolecules
DE102014005782A1 (de) 2014-04-23 2015-10-29 Martin-Luther-Universität Halle-Wittenberg lnjizierbare und implantierbare Trägersysteme auf Basis von modifizierten Poly(dikarbonsäure-multiol estern) zur kontrollierten Wirkstofffreisetzung
JP6557722B2 (ja) 2014-05-30 2019-08-07 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド 核酸の送達のための生分解性脂質
EP3221394A1 (fr) * 2014-11-17 2017-09-27 Roquette Frères Composition à base d'un mélange de polyesters et d'amidon thermoplastique à filmabilité améliorée
KR101891046B1 (ko) * 2014-12-16 2018-08-22 보스톤 싸이엔티픽 싸이메드 인코포레이티드 생분해성 중합체 조성물
US9260550B1 (en) * 2015-01-27 2016-02-16 International Business Machines Corporation Lactide-based acrylate polymers
JP6148701B2 (ja) * 2015-07-31 2017-06-14 ユニベルシテ ドゥ ジュネーブ ２−ヒドロキシアルキル酸から調製されたポリマーを含む組成物
US10570252B2 (en) 2017-03-08 2020-02-25 International Business Machines Corporation Flame retardant lactide monomors for polylactide synthesis
US10035877B1 (en) 2017-03-08 2018-07-31 International Business Machines Corporation Matrix-bondable lactide monomors for polylactide synthesis
US10072121B1 (en) 2017-03-08 2018-09-11 International Business Machines Corporation Bottlebrush polymers derived from poly(methylidenelactide)
US10202489B2 (en) 2017-03-08 2019-02-12 International Business Machines Corporation Lactide copolymers and ring-opened lactide copolymers
EP3743041A1 (en) 2018-01-26 2020-12-02 Apidel SA New spironolactone formulations and their use
CA2994005A1 (fr) * 2018-02-05 2019-08-05 Hydro-Quebec Copolymeres d'unites ester et ether, leurs procedes de fabrication et leurs utilisations
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WO2024064758A2 (en) * 2022-09-21 2024-03-28 Hercules Llc Coating composition comprising a bioresorbable copolymer and an anti-microbial agent

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Also Published As

Publication number Publication date
EP3339348B1 (en) 2019-12-04
PL1883665T3 (pl) 2018-05-30
EP1883665A2 (en) 2008-02-06
JP2014065722A (ja) 2014-04-17
US20180271984A1 (en) 2018-09-27
US8466133B2 (en) 2013-06-18
JP2008538589A (ja) 2008-10-30
PT1883665T (pt) 2017-11-14
US9375482B2 (en) 2016-06-28
CA2605652A1 (en) 2007-02-01
JP2017222712A (ja) 2017-12-21
JP2015038121A (ja) 2015-02-26
US9925267B2 (en) 2018-03-27
JP6346540B2 (ja) 2018-06-20
JP6491614B2 (ja) 2019-03-27
WO2007012979A3 (en) 2007-05-03
DK1883665T3 (da) 2017-11-13
EP1883665B1 (en) 2017-10-11
US20130331464A1 (en) 2013-12-12
CA2605652C (en) 2016-05-24
WO2007012979A2 (en) 2007-02-01
US20150073060A1 (en) 2015-03-12
US10314913B2 (en) 2019-06-11
EP3339348A1 (en) 2018-06-27
US20160367680A1 (en) 2016-12-22
JP5749881B2 (ja) 2015-07-15
JP2016128506A (ja) 2016-07-14
US8741877B2 (en) 2014-06-03
US20090281068A1 (en) 2009-11-12
JP6559198B2 (ja) 2019-08-14

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