ES2632428T3 - Nuevas tiadiazolidinadionas como inhibidores de GSK-3 - Google Patents
Nuevas tiadiazolidinadionas como inhibidores de GSK-3 Download PDFInfo
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- ES2632428T3 ES2632428T3 ES13705492.0T ES13705492T ES2632428T3 ES 2632428 T3 ES2632428 T3 ES 2632428T3 ES 13705492 T ES13705492 T ES 13705492T ES 2632428 T3 ES2632428 T3 ES 2632428T3
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12382066 | 2012-02-24 | ||
| EP12382066 | 2012-02-24 | ||
| PCT/EP2013/053554 WO2013124413A1 (en) | 2012-02-24 | 2013-02-22 | Thiadiazolidinediones as gsk-3 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2632428T3 true ES2632428T3 (es) | 2017-09-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13705492.0T Active ES2632428T3 (es) | 2012-02-24 | 2013-02-22 | Nuevas tiadiazolidinadionas como inhibidores de GSK-3 |
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| Country | Link |
|---|---|
| US (2) | US9371299B2 (enExample) |
| EP (1) | EP2838888B1 (enExample) |
| JP (2) | JP6073377B2 (enExample) |
| AU (2) | AU2013224041B2 (enExample) |
| CA (1) | CA2865351C (enExample) |
| CY (1) | CY1119231T1 (enExample) |
| DK (1) | DK2838888T3 (enExample) |
| ES (1) | ES2632428T3 (enExample) |
| HR (1) | HRP20170964T1 (enExample) |
| HU (1) | HUE035089T2 (enExample) |
| IN (1) | IN2014DN07885A (enExample) |
| LT (1) | LT2838888T (enExample) |
| NZ (1) | NZ630615A (enExample) |
| PL (1) | PL2838888T3 (enExample) |
| PT (1) | PT2838888T (enExample) |
| SI (1) | SI2838888T1 (enExample) |
| WO (1) | WO2013124413A1 (enExample) |
| ZA (1) | ZA201406225B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2838888B1 (en) | 2012-02-24 | 2017-04-12 | ASD Therapeutics Partners LLC | Thiadiazolidinediones as gsk-3 inhibitors |
| BR112015023261A2 (pt) | 2013-03-14 | 2017-07-18 | Massachusetts Inst Technology | composições e métodos para expansão e cultura de células-tronco epiteliais |
| MX388409B (es) * | 2014-06-12 | 2025-03-19 | Cedars Sinai Medical Center | Composiciones y metodos para tratar canceres. |
| CN107073042A (zh) | 2014-09-03 | 2017-08-18 | 布里格海姆妇女医院公司 | 用于产生内耳毛细胞来治疗听力损失的组合物、系统和方法 |
| CA3010610A1 (en) | 2016-01-08 | 2017-07-13 | The Brigham And Women's Hospital, Inc. | Production of differentiated enteroendocrine cells and insulin producing cells |
| US11260130B2 (en) | 2016-03-02 | 2022-03-01 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV |
| US10213511B2 (en) | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| AU2017386417B2 (en) | 2016-12-30 | 2022-07-14 | Frequency Therapeutics, Inc. | 1H-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells |
| WO2020037326A1 (en) | 2018-08-17 | 2020-02-20 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by downregulating foxo |
| WO2020037323A1 (en) | 2018-08-17 | 2020-02-20 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by upregulating jag-1 |
| CN113168150B (zh) * | 2018-10-16 | 2024-05-10 | 意大利技术联盟有限责任公司 | 具有被处理幅材的评估系统的卷绕机和方法 |
| WO2020163812A1 (en) | 2019-02-08 | 2020-08-13 | Frequency Therapeutics, Inc. | Valproic acid compounds and wnt agonists for treating ear disorders |
| WO2022170437A1 (en) * | 2021-02-11 | 2022-08-18 | Venca Research, Inc. | Compositions and methods for treating arrhythmogenic cardiomyopathy |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2166328B1 (es) * | 2000-05-11 | 2003-09-16 | Consejo Superior Investigacion | Inhibidores heterociclicos del enzima gsk 3 utiles en el tratamiento de procesos neurodegenerativos e hiperproliferativos |
| DE60129222T2 (de) * | 2000-05-11 | 2008-03-06 | Consejo Superior de Investigaciónes Científicas | Heterocyclischen inhibitoren von glycogen synthase kinase gsk-3 |
| EP1586318A1 (en) | 2004-04-05 | 2005-10-19 | Neuropharma S.A.U. | Thiadiazolidinones as GSK-3 inhibitors |
| KR100837785B1 (ko) * | 2007-01-17 | 2008-06-13 | 한국화학연구원 | 1,2,4-티아다이아졸리딘-3,5-다이온 화합물을 포함하는염증관련 질환의 치료 및 예방을 위한 약제학적 조성물 |
| EP2838888B1 (en) | 2012-02-24 | 2017-04-12 | ASD Therapeutics Partners LLC | Thiadiazolidinediones as gsk-3 inhibitors |
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2013
- 2013-02-22 EP EP13705492.0A patent/EP2838888B1/en active Active
- 2013-02-22 NZ NZ630615A patent/NZ630615A/en unknown
- 2013-02-22 AU AU2013224041A patent/AU2013224041B2/en active Active
- 2013-02-22 WO PCT/EP2013/053554 patent/WO2013124413A1/en not_active Ceased
- 2013-02-22 LT LTEP13705492.0T patent/LT2838888T/lt unknown
- 2013-02-22 DK DK13705492.0T patent/DK2838888T3/en active
- 2013-02-22 HR HRP20170964TT patent/HRP20170964T1/hr unknown
- 2013-02-22 SI SI201330704T patent/SI2838888T1/sl unknown
- 2013-02-22 US US14/380,623 patent/US9371299B2/en active Active
- 2013-02-22 CA CA2865351A patent/CA2865351C/en active Active
- 2013-02-22 HU HUE13705492A patent/HUE035089T2/hu unknown
- 2013-02-22 PL PL13705492T patent/PL2838888T3/pl unknown
- 2013-02-22 JP JP2014558118A patent/JP6073377B2/ja active Active
- 2013-02-22 PT PT137054920T patent/PT2838888T/pt unknown
- 2013-02-22 ES ES13705492.0T patent/ES2632428T3/es active Active
- 2013-02-22 IN IN7885DEN2014 patent/IN2014DN07885A/en unknown
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2014
- 2014-08-25 ZA ZA2014/06225A patent/ZA201406225B/en unknown
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2016
- 2016-05-16 US US15/155,437 patent/US9469618B2/en active Active
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2017
- 2017-01-04 JP JP2017000211A patent/JP6518270B2/ja active Active
- 2017-07-12 CY CY20171100737T patent/CY1119231T1/el unknown
- 2017-10-20 AU AU2017248556A patent/AU2017248556B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PT2838888T (pt) | 2017-07-18 |
| EP2838888B1 (en) | 2017-04-12 |
| CY1119231T1 (el) | 2018-02-14 |
| HUE035089T2 (hu) | 2018-05-02 |
| AU2017248556A1 (en) | 2017-11-09 |
| HK1207366A1 (en) | 2016-01-29 |
| CA2865351C (en) | 2019-08-20 |
| EP2838888A1 (en) | 2015-02-25 |
| JP2017081974A (ja) | 2017-05-18 |
| CA2865351A1 (en) | 2013-08-29 |
| US20150038538A1 (en) | 2015-02-05 |
| US9371299B2 (en) | 2016-06-21 |
| US9469618B2 (en) | 2016-10-18 |
| US20160257660A1 (en) | 2016-09-08 |
| IN2014DN07885A (enExample) | 2015-04-24 |
| JP6518270B2 (ja) | 2019-05-22 |
| AU2013224041B2 (en) | 2017-08-24 |
| AU2017248556B2 (en) | 2018-08-09 |
| ZA201406225B (en) | 2016-05-25 |
| JP6073377B2 (ja) | 2017-02-01 |
| NZ630615A (en) | 2015-09-25 |
| HRP20170964T1 (hr) | 2017-10-06 |
| SI2838888T1 (sl) | 2017-09-29 |
| DK2838888T3 (en) | 2017-07-17 |
| WO2013124413A1 (en) | 2013-08-29 |
| PL2838888T3 (pl) | 2017-12-29 |
| AU2013224041A1 (en) | 2014-09-25 |
| JP2015508092A (ja) | 2015-03-16 |
| LT2838888T (lt) | 2017-08-10 |
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