ES2631988T1 - Composición farmacéutica compuesta por mioinositol y D-chiro-inositol - Google Patents
Composición farmacéutica compuesta por mioinositol y D-chiro-inositol Download PDFInfo
- Publication number
- ES2631988T1 ES2631988T1 ES12806356.7T ES12806356T ES2631988T1 ES 2631988 T1 ES2631988 T1 ES 2631988T1 ES 12806356 T ES12806356 T ES 12806356T ES 2631988 T1 ES2631988 T1 ES 2631988T1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical composition
- composition according
- chiro
- inositol
- myoinositol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 10
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 title claims abstract 10
- CDAISMWEOUEBRE-LKPKBOIGSA-N 1D-chiro-inositol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O CDAISMWEOUEBRE-LKPKBOIGSA-N 0.000 title claims abstract 5
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 title claims abstract 5
- 229960000367 inositol Drugs 0.000 title claims abstract 5
- 239000000203 mixture Substances 0.000 claims 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims 2
- 239000007901 soft capsule Substances 0.000 claims 2
- PZNPLUBHRSSFHT-RRHRGVEJSA-N 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)COC(=O)CCCCCCCCCCCCCCC PZNPLUBHRSSFHT-RRHRGVEJSA-N 0.000 claims 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims 1
- NPTLAYTZMHJJDP-KTKRTIGZSA-N [3-[3-[3-[3-[3-[3-[3-[3-[3-(2,3-dihydroxypropoxy)-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropyl] (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)COCC(O)CO NPTLAYTZMHJJDP-KTKRTIGZSA-N 0.000 claims 1
- 229960000304 folic acid Drugs 0.000 claims 1
- 235000019152 folic acid Nutrition 0.000 claims 1
- 239000011724 folic acid Substances 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000004530 micro-emulsion Substances 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 210000000287 oocyte Anatomy 0.000 claims 1
- 201000010065 polycystic ovary syndrome Diseases 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000006041 probiotic Substances 0.000 claims 1
- 235000018291 probiotics Nutrition 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 235000012424 soybean oil Nutrition 0.000 claims 1
- 239000003549 soybean oil Substances 0.000 claims 1
- 239000008347 soybean phospholipid Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Una composición farmacéutica que contiene mioinositol y D-chiro-inositol en una proporción de 10:1 a 100: 1, respectivamente.
Claims (9)
- REIVINDICACIONES1. Una composicion farmaceutica que contiene mioinositol y D-chiro-inositol en una proporcion de 10:1 a 100: 1, respectivamente.
- 2. Una composicion farmaceutica segun la reivindicacion 1 en una formula adecuada para la administracion oral.
- 3. Una composicion farmaceutica segun la reivindicacion 2, donde se selecciona dicha formula adecuada para la administracion oral de polvos, soluciones, tabletas, capsulas blandas.
- 4. Una composicion farmaceutica segun una o mas de las reivindicaciones previas, donde se libera dicha composicion mediante probioticos.
- 5. Una composicion farmaceutica segun una o mas de las reivindicaciones previas, donde se libera dicha composicion mediante microemulsiones, micro o nanopartfculas o filomicelas.
- 6. Una composicion farmaceutica segun las reivindicaciones 1-6 para el tratamiento del SOP.
- 7. Una composicion farmaceutica segun las reivindicaciones 1-6 para mejorar la calidad del ovocito.
- 8. Una composicion farmaceutica segun las reivindicaciones 1-7 en forma de capsulas blandas con la siguiente composicion:550 mg mioinositol,13,8 mg D-chiro-inositol,350 mg aceite de soja,100 mg lecitina de soja,50 mg labrafac,50 mg plurol oleique,20 mg geleol,0,24 mg acido folico
- 9. Barras de alimentos que contienen una composicion con mioinositol y D-chiro-inositol en una proporcion comprendida entre 10:1 y 100: 1 respectivamente.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI20110252 | 2011-11-22 | ||
| IT000252A ITFI20110252A1 (it) | 2011-11-22 | 2011-11-22 | Composizione farmaceutica comprendente myo-inositolo e d-chiro-inositolo. |
| PCT/EP2012/073189 WO2013076121A1 (en) | 2011-11-22 | 2012-11-21 | Pharmaceutical composition comprising myo-inositol and d-chiro-inositol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2631988T1 true ES2631988T1 (es) | 2017-09-07 |
| ES2631988T3 ES2631988T3 (es) | 2018-07-12 |
Family
ID=45540947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12806356.7T Active ES2631988T3 (es) | 2011-11-22 | 2012-11-21 | Composición farmacéutica que comprende mioinositol y D-quiro-inositol |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP3424497A1 (es) |
| CY (1) | CY1120438T1 (es) |
| DK (1) | DK2782559T3 (es) |
| ES (1) | ES2631988T3 (es) |
| HR (1) | HRP20181433T1 (es) |
| IT (1) | ITFI20110252A1 (es) |
| LT (1) | LT2782559T (es) |
| PL (1) | PL2782559T3 (es) |
| PT (1) | PT2782559T (es) |
| RS (1) | RS57607B1 (es) |
| SA (1) | SA112340015B1 (es) |
| SI (1) | SI2782559T1 (es) |
| TW (1) | TWI594750B (es) |
| WO (1) | WO2013076121A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106794206A (zh) * | 2014-08-08 | 2017-05-31 | 雀巢产品技术援助有限公司 | 肌醇和一种或多种益生菌以及它们的用途 |
| WO2016020486A1 (en) * | 2014-08-08 | 2016-02-11 | Nestec S.A. | A combination of myo-inositol and zinc and its use |
| BR112017000978A2 (pt) * | 2014-08-08 | 2017-11-21 | Nestec Sa | mioinositol e probióticos e usos |
| ITUA20162575A1 (it) * | 2016-04-13 | 2017-10-13 | S&R Farm S P A | Composizione farmaceutica o nutraceutica per l’uso nel trattamento della sindrome dell’ovaio policistico o di malattie o disturbi correlati ad essa |
| US11898184B2 (en) * | 2017-09-07 | 2024-02-13 | Sweet Sense Inc. | Low glycemic sugar composition |
| IT201700104446A1 (it) | 2017-09-19 | 2019-03-19 | Lo Li Pharma Srl | Compositions, uses and methods for treatment of infertility and subfertility |
| US11484540B2 (en) | 2017-11-23 | 2022-11-01 | Biosearch. S.A. | Method for increasing embryo implantation rate in a female subject suffering polycystic ovary syndrome |
| PL238919B1 (pl) | 2018-02-28 | 2021-10-18 | Verco Spolka Akcyjna | Kompozycja farmaceutyczna zawierająca mio-inozytol i D-chiro- inozytol, do zastosowania w terapeutycznym sposobie obniżania masy ciała u kobiet z zespołem policystycznych jajników |
| WO2020039014A1 (en) * | 2018-08-22 | 2020-02-27 | Société des Produits Nestlé S.A. | Composition comprising isomers of inositol and its use |
| EP3789018A1 (en) * | 2019-09-09 | 2021-03-10 | Servicio Andaluz De Salud | Composition and methods for enhancing or promoting the secretion of ghrelin to promote a healthy metabolic aging |
| IT201900025063A1 (it) | 2019-12-20 | 2021-06-20 | Idi Integratori Dietetici Italiani S R L | Composizioni gastroresistenti comprendi inositolo e/o estratto di gymnema sylvestre, loro composizioni farmaceutiche e nutraceutiche e loro uso |
| RU2757220C1 (ru) * | 2020-06-03 | 2021-10-12 | Общество с ограниченной ответственностью "ОКТАВА ХОЛДИНГ" | Фармацевтическая композиция для профилактики и лечения синдрома поликистозных яичников |
| EP4171540A1 (en) | 2020-09-04 | 2023-05-03 | Société des Produits Nestlé S.A. | Compositions and methods for providing health benefits in an animal |
| EP4000626A1 (en) | 2020-11-16 | 2022-05-25 | concrete flowers GmbH | Pharmaceutical preparation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750348A (en) * | 1989-03-08 | 1998-05-12 | The University Of Virginia Patents Foundation | Method for detecting insulin resistance |
| US5906979A (en) * | 1998-01-27 | 1999-05-25 | Insmed Pharmaceuticals, Inc. | Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility |
| MXPA02003861A (es) | 1999-10-18 | 2003-07-14 | Muscletech Res And Dev Inc | Suplemento alimenticio para incrementar la masa sin desarrollar y la fuerza. |
| JP2006213684A (ja) * | 2005-02-07 | 2006-08-17 | Hokko Chem Ind Co Ltd | インスリン抵抗性改善に用いられる組成物及び健康用食品 |
| ITRM20070341A1 (it) * | 2007-06-20 | 2008-12-21 | Lo Li Pharma Srl | Formulazione integrativa inofolic finalizzata al controllo dell'induzione dell'ovulazione in programmi di procreazione medicalmente assistita |
-
2011
- 2011-11-22 IT IT000252A patent/ITFI20110252A1/it unknown
-
2012
- 2012-11-16 TW TW101142788A patent/TWI594750B/zh active
- 2012-11-20 SA SA112340015A patent/SA112340015B1/ar unknown
- 2012-11-21 PL PL12806356T patent/PL2782559T3/pl unknown
- 2012-11-21 ES ES12806356.7T patent/ES2631988T3/es active Active
- 2012-11-21 EP EP18175950.7A patent/EP3424497A1/en not_active Withdrawn
- 2012-11-21 DK DK12806356.7T patent/DK2782559T3/en active
- 2012-11-21 PT PT12806356T patent/PT2782559T/pt unknown
- 2012-11-21 EP EP12806356.7A patent/EP2782559B1/en active Active
- 2012-11-21 SI SI201231353T patent/SI2782559T1/sl unknown
- 2012-11-21 WO PCT/EP2012/073189 patent/WO2013076121A1/en active Application Filing
- 2012-11-21 RS RS20180973A patent/RS57607B1/sr unknown
- 2012-11-21 LT LTEP12806356.7T patent/LT2782559T/lt unknown
-
2018
- 2018-07-17 CY CY20181100743T patent/CY1120438T1/el unknown
- 2018-09-06 HR HRP20181433TT patent/HRP20181433T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013076121A1 (en) | 2013-05-30 |
| ITFI20110252A1 (it) | 2013-05-23 |
| EP2782559B1 (en) | 2018-06-06 |
| RS57607B1 (sr) | 2018-11-30 |
| HRP20181433T1 (hr) | 2018-10-19 |
| ES2631988T3 (es) | 2018-07-12 |
| LT2782559T (lt) | 2018-06-25 |
| TWI594750B (zh) | 2017-08-11 |
| SA112340015B1 (ar) | 2016-01-21 |
| TW201320992A (zh) | 2013-06-01 |
| PL2782559T3 (pl) | 2018-12-31 |
| SI2782559T1 (sl) | 2018-09-28 |
| CY1120438T1 (el) | 2019-07-10 |
| EP3424497A1 (en) | 2019-01-09 |
| EP2782559A1 (en) | 2014-10-01 |
| DK2782559T3 (en) | 2018-08-27 |
| PT2782559T (pt) | 2018-10-15 |
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