ES2625778T3 - Uso de pregn-4-en-20-in-3-ona para el tratamiento de trastornos depresivos - Google Patents
Uso de pregn-4-en-20-in-3-ona para el tratamiento de trastornos depresivos Download PDFInfo
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- ES2625778T3 ES2625778T3 ES13819136.6T ES13819136T ES2625778T3 ES 2625778 T3 ES2625778 T3 ES 2625778T3 ES 13819136 T ES13819136 T ES 13819136T ES 2625778 T3 ES2625778 T3 ES 2625778T3
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- depressive disorder
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
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| US201261747167P | 2012-12-28 | ||
| PCT/US2013/076497 WO2014105620A1 (en) | 2012-12-28 | 2013-12-19 | Use of pregn-4-en-20-yn-3-one for the treatment of depressive disorders |
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| ES2625778T3 true ES2625778T3 (es) | 2017-07-20 |
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| WO2020087031A1 (en) | 2018-10-26 | 2020-04-30 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| PL3955933T3 (pl) * | 2019-04-15 | 2024-04-29 | Vistagen Therapeutics, Inc. | Leczenie migreny |
| WO2024254005A1 (en) | 2023-06-04 | 2024-12-12 | Vistagen Therapeutics, Inc. | 1,3,5(10),16-estratetraen-3-yl acetate for use in improving psychomotor or cognitive performance |
| US20250312356A1 (en) * | 2024-04-08 | 2025-10-09 | Vistagen Therapeutics, Inc. | Treatment of dysmenorrhea |
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| ES2210243T3 (es) * | 1993-06-15 | 2004-07-01 | Pherin Corporation | Esteroides de androstano utiles como iniciadores del cambio de la funcion hipotalamica humana, composiciones farmaceuticas y procedimientos asociados. |
| US6057439A (en) | 1994-08-04 | 2000-05-02 | Pherin Corporation | Steroids as neurochemical stimulators of the VNO to alleviate symptoms of PMS and anxiety |
| US5563131A (en) * | 1994-08-04 | 1996-10-08 | Pherin Corporation | Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods |
| US6066627A (en) | 1994-08-04 | 2000-05-23 | Pherin Corporation | Steroids as neurochemical initiators of change in human blood levels of LH |
| US5994333A (en) * | 1994-08-04 | 1999-11-30 | Pherin Corporation | Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods |
| US6331534B1 (en) | 1994-08-04 | 2001-12-18 | Pherin Pharmaceuticals, Inc. | Steroids as neurochemical stimulators of the VNO to alleviate pain |
| US6117860A (en) | 1994-08-04 | 2000-09-12 | Pherin Pharmaceuticals, Inc. | Steroids as neurochemical stimulators of the VNO to treat paroxistic tachycardia |
| ATE342721T1 (de) * | 1996-07-23 | 2006-11-15 | Pherin Pharm Inc | Steroide als neurochemische stimulatoren des nasenraumes zur linderung der prämenstrualen symptome |
| US20020123138A1 (en) | 2000-11-30 | 2002-09-05 | Jian Zhang | Human VNO receptor (R1) |
| US20030045514A1 (en) | 2001-05-03 | 2003-03-06 | Louis Monti | 17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors |
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Also Published As
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| CA2894686C (en) | 2021-05-04 |
| EP2938346B1 (en) | 2017-04-05 |
| KR102209475B1 (ko) | 2021-01-28 |
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| HK1210421A1 (en) | 2016-04-22 |
| US10322138B2 (en) | 2019-06-18 |
| AU2013371025B2 (en) | 2018-01-18 |
| WO2014105620A1 (en) | 2014-07-03 |
| CA2894686A1 (en) | 2014-07-03 |
| MX369774B (es) | 2019-11-21 |
| MX2015008454A (es) | 2016-05-16 |
| CN104936600A (zh) | 2015-09-23 |
| CN104936600B (zh) | 2018-08-03 |
| JP6283689B2 (ja) | 2018-02-21 |
| DK2938346T3 (en) | 2017-06-12 |
| AU2013371025A1 (en) | 2015-07-09 |
| EP2938346A1 (en) | 2015-11-04 |
| US20140187524A1 (en) | 2014-07-03 |
| KR20150100884A (ko) | 2015-09-02 |
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