ES2621657T3 - Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos - Google Patents

Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos Download PDF

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Publication number
ES2621657T3
ES2621657T3 ES12158465.0T ES12158465T ES2621657T3 ES 2621657 T3 ES2621657 T3 ES 2621657T3 ES 12158465 T ES12158465 T ES 12158465T ES 2621657 T3 ES2621657 T3 ES 2621657T3
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nucleotide sequence
seq
set forth
nucleic acid
amino acid
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English (en)
Spanish (es)
Inventor
Dae-Kyun Ro
Karyn Newman
Eric M. Paradise
Jay D. Keasling
Mario Ouellet
Rachel Eachus
Kimberly Ho
Timothy Ham
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University of California Berkeley
University of California San Diego UCSD
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University of California Berkeley
University of California San Diego UCSD
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
    • C12Y106/02—Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12Y106/02004—NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
ES12158465.0T 2005-07-05 2006-06-29 Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos Active ES2621657T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69706705P 2005-07-05 2005-07-05
US697067P 2005-07-05

Publications (1)

Publication Number Publication Date
ES2621657T3 true ES2621657T3 (es) 2017-07-04

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Family Applications (2)

Application Number Title Priority Date Filing Date
ES12158465.0T Active ES2621657T3 (es) 2005-07-05 2006-06-29 Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos
ES06785959T Active ES2386554T3 (es) 2005-07-05 2006-06-29 Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos

Family Applications After (1)

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ES06785959T Active ES2386554T3 (es) 2005-07-05 2006-06-29 Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos

Country Status (18)

Country Link
US (2) US8163980B2 (OSRAM)
EP (2) EP1919514B1 (OSRAM)
JP (1) JP2009504138A (OSRAM)
KR (2) KR101487304B1 (OSRAM)
CN (4) CN105950667A (OSRAM)
AP (1) AP3827A (OSRAM)
BR (1) BRPI0612411B8 (OSRAM)
CA (1) CA2613469C (OSRAM)
DK (1) DK1919514T3 (OSRAM)
ES (2) ES2621657T3 (OSRAM)
IL (1) IL188376A (OSRAM)
MX (1) MX2008000200A (OSRAM)
PL (1) PL1919514T3 (OSRAM)
PT (1) PT1919514E (OSRAM)
SG (1) SG176459A1 (OSRAM)
SI (1) SI1919514T1 (OSRAM)
WO (1) WO2007005604A2 (OSRAM)
ZA (1) ZA200800889B (OSRAM)

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EP2024504B2 (en) 2006-05-26 2022-12-14 Amyris, Inc. Production of isoprenoids
EP3020799B1 (en) * 2006-09-26 2020-08-26 The Regents of The University of California Production of isoprenoids and isoprenoid precursors
EP2171085A4 (en) 2007-06-01 2010-07-14 Sapphire Energy SCREENING OF GENETICALLY MODIFIED PHOTOSYNTHETIC ORGANISMS WITH HIGH THROUGHPUT
CN101889068A (zh) 2007-09-11 2010-11-17 蓝宝石能源公司 用光合生物生产有机产物的方法及其产物和组合物
EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
RU2625224C2 (ru) * 2011-11-01 2017-07-12 Фирмениш Са Цитохром p450 и его применение для энзиматического окисления терпенов
JP5827601B2 (ja) 2012-07-04 2015-12-02 住友ゴム工業株式会社 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
SG11201500682WA (en) * 2012-09-07 2015-02-27 Sanofi Sa Fusion proteins for treating a metabolic syndrome
PL224377B1 (pl) * 2012-11-02 2016-12-30 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Szczep Trichoderma atroviride, sposób otrzymywania i zastosowanie szczepu Trichoderma atroviride jako środka biobójczego
RU2654670C2 (ru) * 2013-09-19 2018-05-21 Фирмениш Са Способ получения ароматических спиртов
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EP3283615A4 (en) * 2015-04-15 2018-09-05 William Marsh Rice University Iterative platform for the synthesis of alpha functionalized products
US11697830B2 (en) * 2015-04-15 2023-07-11 Ramon Gonzalez Iterative platform for the synthesis of alpha functionalized products
CN105274109B (zh) * 2015-10-30 2017-12-29 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105177007B (zh) * 2015-10-30 2017-11-10 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105483236A (zh) * 2015-12-26 2016-04-13 吉林省农业科学院 转基因植物中cry1C基因的LAMP检测引物组、试剂盒及检测方法
CN105567685B (zh) * 2016-01-18 2018-07-13 上海交通大学 AaPDR3基因启动子及其应用
MA45611A (fr) 2016-09-20 2019-05-15 22Nd Century Ltd Llc Promoteurs spécifiques des trichomes pour la manipulation de cannabinoïdes et d'autres composés dans des trichomes glandulaires
WO2018111194A1 (en) * 2016-12-16 2018-06-21 Temasek Life Sciences Laboratory Limited Targets for improving terpene production in rhodosporidium toruloides
CN111373045A (zh) 2017-03-24 2020-07-03 特征生物科学公司 水溶性大麻素在植物系统中高水平体内生物合成和分离
EP3679153A4 (en) 2017-07-11 2021-01-06 Trait Biosciences, Inc. GENERATION OF WATER-SOLUBLE CANNABINOID COMPOUNDS IN YEAST AND PLANT CELL SUSPENSION CULTURES AND COMPOSITIONS
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Also Published As

Publication number Publication date
WO2007005604A3 (en) 2008-12-31
PT1919514E (pt) 2012-08-16
KR20080031054A (ko) 2008-04-07
CN106939323A (zh) 2017-07-11
HK1134495A1 (en) 2010-04-30
CN103667370B (zh) 2016-08-10
EP2489672A2 (en) 2012-08-22
EP2489672B1 (en) 2017-01-18
CA2613469A1 (en) 2007-01-11
US8163980B2 (en) 2012-04-24
US8759632B2 (en) 2014-06-24
DK1919514T3 (da) 2012-08-20
CN101495499A (zh) 2009-07-29
SG176459A1 (en) 2011-12-29
MX2008000200A (es) 2008-04-07
SI1919514T1 (sl) 2012-08-31
BRPI0612411B1 (pt) 2020-05-05
ZA200800889B (en) 2009-09-30
KR20130054468A (ko) 2013-05-24
JP2009504138A (ja) 2009-02-05
EP1919514A4 (en) 2009-12-02
IL188376A (en) 2012-12-31
CN106939323B (zh) 2021-07-13
BRPI0612411B8 (pt) 2021-05-25
CN103667370A (zh) 2014-03-26
WO2007005604A2 (en) 2007-01-11
BRPI0612411A2 (pt) 2010-11-09
CN105950667A (zh) 2016-09-21
US20120288905A1 (en) 2012-11-15
AP3827A (en) 2016-09-30
KR101444090B1 (ko) 2014-09-26
PL1919514T3 (pl) 2012-10-31
EP1919514B1 (en) 2012-05-16
AP2013006962A0 (en) 2013-07-31
CN101495499B (zh) 2013-09-04
EP2489672A3 (en) 2013-01-09
CA2613469C (en) 2014-08-12
EP1919514A2 (en) 2008-05-14
BRPI0612411A8 (pt) 2017-12-26
IL188376A0 (en) 2008-04-13
US20100218283A1 (en) 2010-08-26
ES2386554T3 (es) 2012-08-22
KR101487304B1 (ko) 2015-01-28

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