ES2605565T3 - Compuestos de hexahidropirano [3,4-D][1,3]tiazin-2-amina - Google Patents

Compuestos de hexahidropirano [3,4-D][1,3]tiazin-2-amina Download PDF

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Publication number
ES2605565T3
ES2605565T3 ES12770239.7T ES12770239T ES2605565T3 ES 2605565 T3 ES2605565 T3 ES 2605565T3 ES 12770239 T ES12770239 T ES 12770239T ES 2605565 T3 ES2605565 T3 ES 2605565T3
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ES
Spain
Prior art keywords
alkyl
r5ar5b
hydrogen
optionally substituted
cycloalkyl
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ES12770239.7T
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English (en)
Spanish (es)
Inventor
Michael Aaron Brodney
Christopher Ryan BUTLER
Christopher John Helal
Brian Thomas O'neill
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Pfizer Inc
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Pfizer Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES12770239.7T 2011-08-31 2012-08-17 Compuestos de hexahidropirano [3,4-D][1,3]tiazin-2-amina Active ES2605565T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161529367P 2011-08-31 2011-08-31
US201161529367P 2011-08-31
PCT/IB2012/054198 WO2013030713A1 (en) 2011-08-31 2012-08-17 Hexahydropyrano [3,4-d][1,3] thiazin-2-amine compounds

Publications (1)

Publication Number Publication Date
ES2605565T3 true ES2605565T3 (es) 2017-03-15

Family

ID=47010661

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12770239.7T Active ES2605565T3 (es) 2011-08-31 2012-08-17 Compuestos de hexahidropirano [3,4-D][1,3]tiazin-2-amina

Country Status (8)

Country Link
US (2) US8933221B2 (https=)
EP (1) EP2751116B1 (https=)
JP (1) JP6043355B2 (https=)
AR (1) AR087742A1 (https=)
ES (1) ES2605565T3 (https=)
TW (1) TW201326182A (https=)
UY (1) UY34302A (https=)
WO (1) WO2013030713A1 (https=)

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JP7149271B2 (ja) 2016-12-15 2022-10-06 アムジエン・インコーポレーテツド β－セクレターゼ阻害剤としての１，４－チアジンジオキシドおよび１，２，４－チアジアジンジオキシド誘導体ならびに使用方法
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JP7149272B2 (ja) 2016-12-15 2022-10-06 アムジエン・インコーポレーテツド β－セクレターゼ阻害剤としてのチアジン誘導体および使用方法
CN107892697B (zh) 2016-12-26 2020-11-03 郑州泰基鸿诺医药股份有限公司 一种[1,3]噻嗪-2-胺类化合物及应用，药物组合物
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Also Published As

Publication number Publication date
US8933221B2 (en) 2015-01-13
JP2014525432A (ja) 2014-09-29
AR087742A1 (es) 2014-04-16
US20130053373A1 (en) 2013-02-28
WO2013030713A1 (en) 2013-03-07
JP6043355B2 (ja) 2016-12-14
EP2751116B1 (en) 2016-10-12
US20150087637A1 (en) 2015-03-26
UY34302A (es) 2013-04-05
TW201326182A (zh) 2013-07-01
EP2751116A1 (en) 2014-07-09
US9550795B2 (en) 2017-01-24

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