ES2570158T3 - Tratamiento de la isquemia de extremidades - Google Patents
Tratamiento de la isquemia de extremidadesInfo
- Publication number
- ES2570158T3 ES2570158T3 ES10703115T ES10703115T ES2570158T3 ES 2570158 T3 ES2570158 T3 ES 2570158T3 ES 10703115 T ES10703115 T ES 10703115T ES 10703115 T ES10703115 T ES 10703115T ES 2570158 T3 ES2570158 T3 ES 2570158T3
- Authority
- ES
- Spain
- Prior art keywords
- limb ischemia
- treatment
- disease
- critical limb
- buerger
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
Abstract
El uso de células madre neuronales en la fabricación de un medicamento para el tratamiento de un paciente que padece arteriopatía periférica, en el que la enfermedad es isquemia de extremidades aguda o crítica, enfermedad de Buerger o isquemia de extremidades crítica en la diabetes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0902034.8A GB0902034D0 (en) | 2009-02-06 | 2009-02-06 | Method |
PCT/GB2010/050185 WO2010089605A1 (en) | 2009-02-06 | 2010-02-05 | Treatment of limb ischemia |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2570158T3 true ES2570158T3 (es) | 2016-05-17 |
Family
ID=40469746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES10703115T Active ES2570158T3 (es) | 2009-02-06 | 2010-02-05 | Tratamiento de la isquemia de extremidades |
Country Status (8)
Country | Link |
---|---|
US (2) | US8932577B2 (es) |
EP (1) | EP2393920B1 (es) |
JP (2) | JP5845089B2 (es) |
AU (1) | AU2010212147B2 (es) |
CA (1) | CA2747308C (es) |
ES (1) | ES2570158T3 (es) |
GB (1) | GB0902034D0 (es) |
WO (1) | WO2010089605A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0822246D0 (en) | 2008-12-05 | 2009-01-14 | Reneuron Ltd | Composition |
GB0902034D0 (en) | 2009-02-06 | 2009-03-11 | Reneuron Ltd | Method |
MX348419B (es) | 2010-08-19 | 2017-06-12 | F Hoffmann-La Roche Ag * | Conversion de celulas somaticas a celulas madre, neurales reprogramadas, inducidas (irnscs). |
EP2840957B1 (en) * | 2012-04-27 | 2024-01-03 | Stryker European Operations Limited | Optical coherent imaging medical device and method |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4125373A1 (de) | 1991-07-31 | 1993-02-04 | Siemens Ag | Sensorschlauch zur ueberwachung eines mediums |
GB9518606D0 (en) | 1995-09-12 | 1995-11-15 | Inst Of Psychiatry | Neural transplantation |
US5968829A (en) | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
EP1060242A4 (en) * | 1998-01-23 | 2003-09-17 | Imclone Systems Inc | PURIFIED POPULATIONS OF STEM CELLS |
JP4740452B2 (ja) | 1998-03-18 | 2011-08-03 | オシリス セラピューティクス,インコーポレイテッド | 移植で免疫応答の予防と処置のための間葉幹細胞を利用する方法、組成物およびその使用法 |
US6045990A (en) | 1998-07-09 | 2000-04-04 | Baust; John M. | Inclusion of apoptotic regulators in solutions for cell storage at low temperature |
WO2000018414A1 (en) | 1998-09-29 | 2000-04-06 | Diacrin, Inc. | Transplantation of neural cells for the treatment of ischemic damage due to stroke |
GB9904281D0 (en) | 1999-02-24 | 1999-04-21 | Reneuron Ltd | Transplantation |
GB9907243D0 (en) | 1999-03-29 | 1999-05-26 | Reneuron Ltd | Therapy |
US6399384B1 (en) | 1999-09-17 | 2002-06-04 | Reneuron Limited | Conditional immortalization of cells |
US6465215B1 (en) | 1999-12-14 | 2002-10-15 | Reneuron Limited | Identification of cells for transplantation |
US20070048726A1 (en) | 2000-01-14 | 2007-03-01 | Biolife Solutions, Inc. | Methods and Compositions for the Control of Molecular-Based Cell Death During Preservation of Cells, Tissues or Organs in a Gel-Like State |
DE60142553D1 (de) | 2000-02-11 | 2010-08-26 | Children S Hospital Of Orange | Isolierung und transplantation von retinalen stammzellen |
JP2002171965A (ja) * | 2000-12-04 | 2002-06-18 | Kansai Tlo Kk | 骨髄単核球細胞の分離、濃縮方法及び血管再生剤 |
GB0125773D0 (en) | 2001-10-26 | 2001-12-19 | Reneuron Ltd | Constructs |
JP2005514926A (ja) * | 2002-01-14 | 2005-05-26 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ | 新規ほ乳類多分化能幹細胞および組成物、その調製方法および投与方法 |
EP1576117A4 (en) | 2002-07-19 | 2006-02-01 | Vesta Therapeutics Inc | METHOD FOR OBTAINING VIABLE HUMAN LIVER CELLS, INCLUDING STEM CELLS / HEPATIC PRECURSORS |
US7470538B2 (en) | 2002-12-05 | 2008-12-30 | Case Western Reserve University | Cell-based therapies for ischemia |
WO2005014792A2 (en) | 2003-08-08 | 2005-02-17 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Preservation of biomaterials with transported preservation agents |
CA2536655A1 (en) | 2003-09-12 | 2005-03-24 | Reneuron Limited | Immortalisation of mammalian cells and therapeutic applications of said cells |
JP4481706B2 (ja) | 2004-03-31 | 2010-06-16 | 独立行政法人科学技術振興機構 | 脳梗塞疾患モデルマウス |
GB0420963D0 (en) | 2004-09-21 | 2004-10-20 | Reneuron Ltd | Hepatocyte |
ES2294650T3 (es) | 2004-09-30 | 2008-04-01 | Reneuron Limited | Linea celular. |
WO2006055685A2 (en) * | 2004-11-17 | 2006-05-26 | Neuralstem, Inc. | Transplantation of human neural cells for treatment of neurodegenerative conditions |
JP4734669B2 (ja) | 2005-02-04 | 2011-07-27 | 独立行政法人産業技術総合研究所 | ヒト歯乳頭からの幹細胞及びその利用方法 |
CA2609507C (en) | 2005-05-26 | 2014-10-21 | Intercytex Limited | Tissue repair using allogenic dermal fibroblasts |
WO2006130433A2 (en) | 2005-05-27 | 2006-12-07 | Viacell, Inc. | Treatment of ischemia using stem cells |
JP2009502308A (ja) * | 2005-07-28 | 2009-01-29 | ブレインガード・カンパニー・リミテッド | 幹細胞構造支持体としての炭素ナノチューブ |
EP1789435B1 (en) | 2005-09-12 | 2010-02-24 | Industry Foundation of Chonnam National University | A method for production of mature natural killer cell |
GB0522564D0 (en) | 2005-11-04 | 2005-12-14 | Reneuron Ltd | Cells |
GB0703188D0 (en) | 2007-02-19 | 2007-03-28 | Roger Land Building | Large scale production of stem cells |
WO2008152640A2 (en) | 2007-06-13 | 2008-12-18 | Pluristem Ltd. | Three dimensional biocompatible scaffolds for ex-vivo expansion and transplantation of stem cells |
KR20100042654A (ko) * | 2007-08-08 | 2010-04-26 | 교와 핫꼬 기린 가부시키가이샤 | 단리된 세포 집단 |
ES2588438T3 (es) | 2008-03-27 | 2016-11-02 | Biolife Solutions, Inc. | Materiales y métodos para la recogida hipotérmica de sangre entera |
GB0822246D0 (en) | 2008-12-05 | 2009-01-14 | Reneuron Ltd | Composition |
GB0902034D0 (en) * | 2009-02-06 | 2009-03-11 | Reneuron Ltd | Method |
GB201011589D0 (en) | 2010-07-09 | 2010-08-25 | Reneuron Ltd | Therapeutic cells |
-
2009
- 2009-02-06 GB GBGB0902034.8A patent/GB0902034D0/en not_active Ceased
-
2010
- 2010-02-05 US US13/141,453 patent/US8932577B2/en active Active
- 2010-02-05 EP EP10703115.5A patent/EP2393920B1/en active Active
- 2010-02-05 WO PCT/GB2010/050185 patent/WO2010089605A1/en active Application Filing
- 2010-02-05 ES ES10703115T patent/ES2570158T3/es active Active
- 2010-02-05 JP JP2011548784A patent/JP5845089B2/ja active Active
- 2010-02-05 CA CA2747308A patent/CA2747308C/en active Active
- 2010-02-05 AU AU2010212147A patent/AU2010212147B2/en active Active
-
2014
- 2014-05-14 JP JP2014100363A patent/JP2014167017A/ja active Pending
- 2014-08-04 US US14/450,733 patent/US9410122B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP2014167017A (ja) | 2014-09-11 |
AU2010212147A1 (en) | 2011-07-07 |
US8932577B2 (en) | 2015-01-13 |
JP5845089B2 (ja) | 2016-01-20 |
EP2393920A1 (en) | 2011-12-14 |
WO2010089605A1 (en) | 2010-08-12 |
US20120093786A1 (en) | 2012-04-19 |
EP2393920B1 (en) | 2016-02-03 |
US9410122B2 (en) | 2016-08-09 |
AU2010212147B2 (en) | 2014-03-20 |
JP2012516884A (ja) | 2012-07-26 |
US20140341868A1 (en) | 2014-11-20 |
GB0902034D0 (en) | 2009-03-11 |
CA2747308C (en) | 2017-01-03 |
CA2747308A1 (en) | 2010-08-12 |
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