ES2561316T3 - Detección de la predisposición genética a estados asociados con la osteoartritis - Google Patents

Detección de la predisposición genética a estados asociados con la osteoartritis Download PDF

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Publication number
ES2561316T3
ES2561316T3 ES09740020.4T ES09740020T ES2561316T3 ES 2561316 T3 ES2561316 T3 ES 2561316T3 ES 09740020 T ES09740020 T ES 09740020T ES 2561316 T3 ES2561316 T3 ES 2561316T3
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Spain
Prior art keywords
subject
osteoarthritis
allele
progression
disease
Prior art date
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Active
Application number
ES09740020.4T
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English (en)
Spanish (es)
Inventor
Jack F. Bukowski
Nazneen Aziz
Hwa-Ying Wang
Kenneth Huttner
Steven B Abramson
Mukundan Attur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Interleukin Genetics Inc
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Interleukin Genetics Inc
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Publication of ES2561316T3 publication Critical patent/ES2561316T3/es
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES09740020.4T 2008-05-02 2009-05-04 Detección de la predisposición genética a estados asociados con la osteoartritis Active ES2561316T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4999208P 2008-05-02 2008-05-02
US49992P 2008-05-02
US11874408P 2008-12-01 2008-12-01
US118744P 2008-12-01
PCT/US2009/042746 WO2009135218A2 (en) 2008-05-02 2009-05-04 Detecting genetic predisposition to osteoarthritis associated conditions

Publications (1)

Publication Number Publication Date
ES2561316T3 true ES2561316T3 (es) 2016-02-25

Family

ID=41210581

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09740020.4T Active ES2561316T3 (es) 2008-05-02 2009-05-04 Detección de la predisposición genética a estados asociados con la osteoartritis
ES15193948T Active ES2708826T3 (es) 2008-05-02 2009-05-04 Detección de la predisposición genética a afecciones asociadas a la osteoartritis

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES15193948T Active ES2708826T3 (es) 2008-05-02 2009-05-04 Detección de la predisposición genética a afecciones asociadas a la osteoartritis

Country Status (9)

Country Link
US (2) US20100098775A1 (cg-RX-API-DMAC7.html)
EP (3) EP2283156B1 (cg-RX-API-DMAC7.html)
JP (3) JP5762282B2 (cg-RX-API-DMAC7.html)
AU (1) AU2009242490B2 (cg-RX-API-DMAC7.html)
CA (1) CA2723239C (cg-RX-API-DMAC7.html)
DK (2) DK2283156T3 (cg-RX-API-DMAC7.html)
ES (2) ES2561316T3 (cg-RX-API-DMAC7.html)
NZ (1) NZ589034A (cg-RX-API-DMAC7.html)
WO (1) WO2009135218A2 (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2283156T3 (en) * 2008-05-02 2016-02-15 Interleukin Genetics Inc Detection of genetic predisposition to conditions associated with osteoarthritis
US20120115137A1 (en) * 2010-08-31 2012-05-10 Kornman Kenneth S Methods of Predicting Osteoarthritis
RS58131B1 (sr) * 2012-08-06 2019-02-28 Merck Patent Gmbh Prognoza biomarkerima u oboljenjima hrskavice
ES2660818T3 (es) * 2012-08-06 2018-03-26 Merck Patent Gmbh Marcadores genéticos para predecir la capacidad de respuesta a un compuesto de FGF-18
CA3011363A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
HRP20220737T1 (hr) 2017-09-29 2022-09-02 Merck Patent Gmbh Upalni biomarkeri za predviđanje odgovaranja na spoj fgf-18
US11513128B2 (en) 2017-09-29 2022-11-29 Merck Patent Gmbh Metabolic biomarkers for predicting responsiveness to FGF-18 compound
HRP20240665T1 (hr) 2018-09-10 2024-08-16 Merck Patent Gmbh Markeri korisni u strategijama obogaćivanja za liječenje osteoartritisa
US12370240B2 (en) 2018-11-28 2025-07-29 Genascence Corporation Methods and compositions for treating osteoarthritis
EP3980561A1 (en) 2019-06-06 2022-04-13 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
EP4007819A4 (en) * 2019-08-02 2023-08-09 New York University METHODS AND COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

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GB8311018D0 (en) 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4998617A (en) 1986-09-15 1991-03-12 Laura Lupton Inc Facial cosmetic liquid make up kit
US4968607A (en) * 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
EP1262564A3 (en) 1993-01-07 2004-03-31 Sequenom, Inc. Dna sequencing by mass spectrometry
US5593826A (en) 1993-03-22 1997-01-14 Perkin-Elmer Corporation, Applied Biosystems, Inc. Enzymatic ligation of 3'amino-substituted oligonucleotides
US5686246A (en) * 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
US5942390A (en) 1996-01-12 1999-08-24 Cedars-Sinai Medical Center Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism
US5698399A (en) 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
GB9621129D0 (en) * 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
GB9706359D0 (en) * 1997-03-27 1997-05-14 Gemini International Holdings Polymorphisms of an il-1 receptor antagonist gene
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
CN1751127A (zh) * 2002-01-25 2006-03-22 白介素遗传公司 Il-1基因簇和相关的炎性多态性和单倍型
EP2386657B1 (en) * 2003-11-26 2014-01-08 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
US20090253585A1 (en) * 2005-11-30 2009-10-08 Luda Diatchenko Identification of Genetic Polymorphic Variants Associated With Somatosensory Disorders and Methods of Using the Same
DK2283156T3 (en) * 2008-05-02 2016-02-15 Interleukin Genetics Inc Detection of genetic predisposition to conditions associated with osteoarthritis
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Also Published As

Publication number Publication date
JP2018038436A (ja) 2018-03-15
EP2283156A2 (en) 2011-02-16
US20160340734A1 (en) 2016-11-24
EP3059323A1 (en) 2016-08-24
US20100098775A1 (en) 2010-04-22
JP5762282B2 (ja) 2015-08-12
WO2009135218A3 (en) 2010-04-01
NZ589034A (en) 2012-10-26
CA2723239A1 (en) 2009-11-05
DK2283156T3 (en) 2016-02-15
AU2009242490B2 (en) 2015-01-22
JP2011520433A (ja) 2011-07-21
EP2283156B1 (en) 2015-11-11
DK3059323T3 (en) 2019-03-04
ES2708826T3 (es) 2019-04-11
EP3467126A1 (en) 2019-04-10
JP6263499B2 (ja) 2018-01-17
WO2009135218A2 (en) 2009-11-05
CA2723239C (en) 2020-07-21
JP2015211677A (ja) 2015-11-26
AU2009242490A1 (en) 2009-11-05
EP3059323B1 (en) 2018-12-12

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