ES2555172T3 - Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad - Google Patents

Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad Download PDF

Info

Publication number
ES2555172T3
ES2555172T3 ES08772390.4T ES08772390T ES2555172T3 ES 2555172 T3 ES2555172 T3 ES 2555172T3 ES 08772390 T ES08772390 T ES 08772390T ES 2555172 T3 ES2555172 T3 ES 2555172T3
Authority
ES
Spain
Prior art keywords
agent
patient
seq
anxiety
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08772390.4T
Other languages
English (en)
Spanish (es)
Inventor
Andrew Tasker
Tracy Doucette
Michael Tymianski
Kenneth Mendoza
Michael P. Belmares
David Garman
Peter S. Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NoNO Inc
Original Assignee
NoNO Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NoNO Inc filed Critical NoNO Inc
Application granted granted Critical
Publication of ES2555172T3 publication Critical patent/ES2555172T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1787Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES08772390.4T 2007-07-03 2008-07-02 Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad Active ES2555172T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94789207P 2007-07-03 2007-07-03
US947892P 2007-07-03
PCT/US2008/069085 WO2009006548A2 (en) 2007-07-03 2008-07-02 Treatment for anxiety

Publications (1)

Publication Number Publication Date
ES2555172T3 true ES2555172T3 (es) 2015-12-29

Family

ID=40226818

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08772390.4T Active ES2555172T3 (es) 2007-07-03 2008-07-02 Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad

Country Status (10)

Country Link
US (2) US8008253B2 (enExample)
EP (1) EP2175873B1 (enExample)
JP (2) JP5775303B2 (enExample)
KR (1) KR101604428B1 (enExample)
CN (1) CN101827604B (enExample)
AU (1) AU2008272903B2 (enExample)
CA (1) CA2692412C (enExample)
DK (1) DK2175873T3 (enExample)
ES (1) ES2555172T3 (enExample)
WO (1) WO2009006548A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
JP6005357B2 (ja) * 2008-05-16 2016-10-12 ノノ インコーポレイテッド てんかんの治療
AU2009288088B2 (en) * 2008-09-03 2014-12-04 Nono Inc. Agents and methods for treatment of pain
WO2013163562A2 (en) * 2012-04-27 2013-10-31 Indiana University Research And Technology Corporation Compositions and methods for treating ptsd and related diseases
CN105705605B (zh) 2013-11-05 2018-07-31 三菱化学株式会社 粘合剂组合物
CN106104658B (zh) 2014-03-10 2019-11-29 三菱化学株式会社 图像显示装置构成用层叠体的制造方法
KR102605540B1 (ko) * 2014-05-28 2023-11-22 노노 인코포레이티드 Tat-nr2b9c의 클로라이드 염
WO2017093354A1 (en) 2015-11-30 2017-06-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Nmdar antagonists for the treatment of diseases associated with angiogenesis
WO2017138544A1 (ja) 2016-02-08 2017-08-17 三菱ケミカル株式会社 透明両面粘着シート及び粘着シート積層体
KR102652894B1 (ko) 2016-02-08 2024-04-01 미쯔비시 케미컬 주식회사 투명 양면 점착 시트 및 점착 시트 적층체
ES2869300T3 (es) * 2016-04-27 2021-10-25 Biocells Beijing Biotech Co Ltd Péptido terapéutico para las lesiones relacionadas con la neurotoxicidad excitadora
CN107312069B (zh) * 2016-04-27 2018-11-06 拜西欧斯(北京)生物技术有限公司 兴奋性神经毒性相关损伤的治疗肽
CN106632601B (zh) * 2016-11-16 2020-10-20 中国科学院昆明动物研究所 一种阻断突触长时程增强(ltp)的短肽及其应用
EA039314B1 (ru) * 2017-07-05 2022-01-12 Биоселз (Бейдзин) Биотек Ко., Лтд. Фармацевтически приемлемые соли полипептидов и их применение
WO2019061395A1 (zh) * 2017-09-30 2019-04-04 拜西欧斯(北京)生物技术有限公司 兴奋性神经毒性相关损伤的治疗肽组合物
FR3075038B1 (fr) 2017-12-15 2020-03-06 Melchior Material And Life Science France Utilisation de la fluoroethylnormemantine pour la prevention de l'apparition et le traitement de l'anxiete
TW202132325A (zh) * 2019-11-05 2021-09-01 國立大學法人京都大學 胜肽、組成物以及治療、預防或改善情緒障礙之方法
CN111285923B (zh) * 2020-03-05 2023-02-03 成都奥达生物科技有限公司 一种psd-95抑制剂
CN113735938B (zh) 2021-07-30 2024-11-08 英纳氏(珠海)药业有限公司 一种神经保护多肽化合物及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6723838B1 (en) * 1998-04-22 2004-04-20 Johns Hopkins University Signal transducing synaptic molecules and uses thereof
US20060148711A1 (en) * 1999-05-14 2006-07-06 Arbor Vita Corporation Molecular interactions in neurons
US6942981B1 (en) * 1999-05-14 2005-09-13 Arbor Vita Corporation Method of determining interactions with PDZ-domain polypeptides
US7595297B2 (en) * 1999-06-02 2009-09-29 Michael Tymianski Method of reducing injury to mammalian cells
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6432985B2 (en) * 2000-04-25 2002-08-13 Hoffmann-La Roche Inc. Neuroprotective substituted piperidine compounds with activity as NMDA NR2B subtype selective antagonists
WO2002000629A1 (en) 2000-06-26 2002-01-03 Merck & Co., Inc. Iminopyrimidine nmda nr2b receptor antagonists
WO2004045535A2 (en) 2002-11-14 2004-06-03 Arbor Vita Corporation Molecular interactions in neurons
FI20012082A0 (fi) * 2001-10-26 2001-10-26 Paeivi Liesi Biologisesti aktiiviset peptidit hermovauroiden korjaamiseksi
US6713490B2 (en) 2002-04-26 2004-03-30 Pfizer, Inc. 3,4-dihydroquinolin-2(1H)-one compounds as NR2B receptor antagonists
GB0303613D0 (en) * 2003-02-17 2003-03-19 Novartis Ag Use of organic compounds
WO2005017203A2 (en) * 2003-07-11 2005-02-24 Yale University Systems and methods for diagnosing and treating psychological and behavioral conditions
AU2004289290A1 (en) * 2003-11-12 2005-05-26 Merck & Co., Inc. 4-phenyl piperdine sulfonyl glycine transporter inhibitors
HU226977B1 (en) * 2004-07-29 2010-04-28 Richter Gedeon Nyrt Kynurenic acid amide derivatives, pharmaceutical compositions containing them and process for producing them
US20060167075A1 (en) * 2005-01-25 2006-07-27 Pearson James P Modulators of FAAH
US20060216331A1 (en) * 2005-02-28 2006-09-28 Lines Thomas C Composition for treating mental health disorders
WO2007002395A1 (en) * 2005-06-23 2007-01-04 Arbor Vita Corporation Methods and compositions for modulating cox
KR101384572B1 (ko) * 2005-12-30 2014-04-24 아버 비타 코포레이션 Pdz 상호작용의 소형 분자 억제제
US8262847B2 (en) * 2006-12-29 2012-09-11 Lam Research Corporation Plasma-enhanced substrate processing method and apparatus
US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
US8080518B2 (en) * 2007-12-05 2011-12-20 Arbor Vita Corporation Co-administration of an agent linked to an internalization peptide with an anti-inflammatory

Also Published As

Publication number Publication date
CA2692412A1 (en) 2009-01-08
WO2009006548A2 (en) 2009-01-08
US8536129B2 (en) 2013-09-17
JP5775303B2 (ja) 2015-09-09
KR20100038366A (ko) 2010-04-14
US20120083449A1 (en) 2012-04-05
CA2692412C (en) 2017-02-07
WO2009006548A3 (en) 2009-03-19
EP2175873B1 (en) 2015-11-11
AU2008272903A1 (en) 2009-01-08
KR101604428B1 (ko) 2016-03-17
EP2175873A4 (en) 2011-10-05
JP2010532761A (ja) 2010-10-14
AU2008272903B2 (en) 2013-08-29
CN101827604A (zh) 2010-09-08
US8008253B2 (en) 2011-08-30
CN101827604B (zh) 2014-05-07
US20090036376A1 (en) 2009-02-05
JP2014129353A (ja) 2014-07-10
EP2175873A2 (en) 2010-04-21
AU2008272903A8 (en) 2010-05-06
DK2175873T3 (en) 2015-12-14

Similar Documents

Publication Publication Date Title
ES2555172T3 (es) Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad
ES2446306T3 (es) Uso de un inhibidor de psd-95 tratamiento para la epilepsia
ES2446292T3 (es) Tratamiento del accidente cerebrovascular y otras enfermedades sin inhibir los canales de calcio de tipo N
ES2804424T3 (es) Péptido y composición del mismo para usar en el tratamiento del accidente cerebrovascular con fiebre
JP5426175B2 (ja) 線維症及び組織における他の形の病理学的沈着を予防及び除去することができるghrp−6を含む薬剤組成物
ES2765281T3 (es) Coadministración de un agente unido a un péptido de interiorización con un agente antiinflamatorio
Pulga et al. Anxiolytic‐and panicolytic‐like effects of Neuropeptide S in the mouse elevated T‐maze
ES2283120T3 (es) Utilizacion de inhibidores de la proteina quinasa c epsilo en el tratamiento del dolor.
Edwards et al. Assessment of therapeutic window for poly‐arginine‐18D (R18D) in a P7 rat model of perinatal hypoxic‐ischaemic encephalopathy
ES2895154T3 (es) Engrailed para su uso en el tratamiento de daños en el ADN en un paciente que padece la enfermedad de Parkinson
ES2550792T3 (es) Tratamiento de trastornos del estado de ánimo y de ansiedad
ES2800073T3 (es) Uso del péptido qbp1 para la prevención o el tratamiento del trastorno del estrés postraumático, el síndrome de estrés agudo y/o el síndrome de adaptación general
ES2339097B1 (es) Mejoras en el objeto de la patente principal n. p200702172, por "pleitrofina (ptn) y midkina (mk) para el tratamiento de la adiccion al consumo y la toxicidad producida por drogas de abuso.
Donev Ion Channels as Therapeutic Targets, Part B
Sutherland Acetylcholine transporter could be muscular dystrophy's missing link
CN111107869A (zh) 细胞周期蛋白依赖性激酶5(cdk5)抑制肽