ES2544265T3 - Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2 - Google Patents

Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2 Download PDF

Info

Publication number
ES2544265T3
ES2544265T3 ES10741738.8T ES10741738T ES2544265T3 ES 2544265 T3 ES2544265 T3 ES 2544265T3 ES 10741738 T ES10741738 T ES 10741738T ES 2544265 T3 ES2544265 T3 ES 2544265T3
Authority
ES
Spain
Prior art keywords
snp
seq
allele
igf2
snps
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10741738.8T
Other languages
English (en)
Spanish (es)
Inventor
Jared Ordway
Rebecca Maloney
Nathan Lakey
Muhammad A. Budiman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Genomics LLC
Original Assignee
Orion Genomics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Genomics LLC filed Critical Orion Genomics LLC
Application granted granted Critical
Publication of ES2544265T3 publication Critical patent/ES2544265T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
ES10741738.8T 2009-02-11 2010-02-11 Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2 Active ES2544265T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20745009P 2009-02-11 2009-02-11
US207450P 2009-02-11
PCT/US2010/023939 WO2010093820A2 (en) 2009-02-11 2010-02-11 Combinations of polymorphisms for determining allele-specific expression of igf2

Publications (1)

Publication Number Publication Date
ES2544265T3 true ES2544265T3 (es) 2015-08-28

Family

ID=42562280

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10741738.8T Active ES2544265T3 (es) 2009-02-11 2010-02-11 Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2

Country Status (7)

Country Link
US (1) US20100286926A1 (enExample)
EP (2) EP2396429B1 (enExample)
JP (2) JP5748672B2 (enExample)
AU (1) AU2010213727A1 (enExample)
CA (1) CA2751758A1 (enExample)
ES (1) ES2544265T3 (enExample)
WO (1) WO2010093820A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2453108T3 (es) * 2007-08-06 2014-04-04 Orion Genomics, Llc Nuevos polimorfismos de un único nucleótido y combinaciones de polimorfismos nuevos y conocidos para determinar la expresión específica de alelo del gen IGF2
EP3414340B1 (en) * 2016-02-12 2023-08-09 CureVac SE Method for analyzing rna
US11920174B2 (en) 2016-03-03 2024-03-05 CureVac SE RNA analysis by total hydrolysis and quantification of released nucleosides
KR101845711B1 (ko) 2016-11-11 2018-04-09 대한민국 Ociad2 유전자 유래의 유전체 각인 판별용 snp 마커 및 이를 이용한 판별 방법
US12222354B2 (en) 2021-03-19 2025-02-11 Quest Diagnostics Investments Llc Identification and quantitation of insulin-like growth factor-I variants by mass spectrometry
AU2023248408A1 (en) * 2022-04-07 2024-10-31 Quest Diagnostics Investments Llc Detection of insulin-like growth factor-2 variants by mass spectrometry

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
NO870613L (no) 1986-03-05 1987-09-07 Molecular Diagnostics Inc Deteksjon av mikroorganismer i en prŸve inneholdende nukleinsyre.
US5604099A (en) 1986-03-13 1997-02-18 Hoffmann-La Roche Inc. Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
CA1284931C (en) 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US5310893A (en) 1986-03-31 1994-05-10 Hoffmann-La Roche Inc. Method for HLA DP typing
US4851331A (en) 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
CA1340843C (en) 1987-07-31 1999-12-07 J. Lawrence Burg Selective amplification of target polynucleotide sequences
DE3803275A1 (de) 1988-02-04 1989-08-17 Dornier Medizintechnik Piezoelektrische stosswellenquelle
CA1340807C (en) 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
EP0451141B1 (en) 1988-05-20 1998-11-18 F. Hoffmann-La Roche Ag Immobilized sequence-specific probes
US5118801A (en) 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
US5639611A (en) 1988-12-12 1997-06-17 City Of Hope Allele specific polymerase chain reaction
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5137806A (en) 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
US5955589A (en) 1991-12-24 1999-09-21 Isis Pharmaceuticals Inc. Gapped 2' modified oligonucleotides
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
JP2985446B2 (ja) 1990-10-31 1999-11-29 東ソー株式会社 核酸の検出及び測定方法
IE913930A1 (en) 1990-11-13 1992-06-17 Siska Diagnostics Nucleic acid amplification by two-enzyme, self-sustained¹sequence replication
YU187991A (sh) 1990-12-11 1994-09-09 Hoechst Aktiengesellschaft 3-(2)-amino-ali tiol-modifikovani, s fluorescentnom bojom vezani nukleozidi, nukleotidi i oligonukleotidi, postupak za njihovo dobijanje i njihova upotreba
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
EP0540997A1 (en) 1991-11-05 1993-05-12 F. Hoffmann-La Roche Ag Methods and reagents for HLA class I DNA typing
US6033854A (en) 1991-12-16 2000-03-07 Biotronics Corporation Quantitative PCR using blocking oligonucleotides
US5652099A (en) 1992-02-12 1997-07-29 Conrad; Michael J. Probes comprising fluorescent nucleosides and uses thereof
EP0655090B1 (en) 1992-04-27 2000-12-27 The Trustees Of Dartmouth College Detection of gene sequences in biological fluids
WO1995006137A1 (en) 1993-08-27 1995-03-02 Australian Red Cross Society Detection of genes
AU8126694A (en) * 1993-10-26 1995-05-22 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
US5446137B1 (en) 1993-12-09 1998-10-06 Behringwerke Ag Oligonucleotides containing 4'-substituted nucleotides
DE4415370A1 (de) 1994-05-02 1995-11-09 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
US5491063A (en) 1994-09-01 1996-02-13 Hoffmann-La Roche Inc. Methods for in-solution quenching of fluorescently labeled oligonucleotide probes
DE4438918A1 (de) 1994-11-04 1996-05-09 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
US5571673A (en) 1994-11-23 1996-11-05 Hoffmann-La Roche Inc. Methods for in-solution quenching of fluorescently labeled oligonucleotide probes
US6117635A (en) 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6235474B1 (en) * 1996-12-30 2001-05-22 The Johns Hopkins University Methods and kits for diagnosing and determination of the predisposition for diseases
EP0866071B1 (en) 1997-03-20 2004-10-20 F. Hoffmann-La Roche Ag Modified primers
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6180349B1 (en) 1999-05-18 2001-01-30 The Regents Of The University Of California Quantitative PCR method to enumerate DNA copy number
US7097976B2 (en) * 2002-06-17 2006-08-29 Affymetrix, Inc. Methods of analysis of allelic imbalance
WO2004003003A1 (en) 2002-06-27 2004-01-08 The Johns Hopkins University School Of Medicine Methods for identifying cancer risk
US9797005B2 (en) * 2005-11-23 2017-10-24 University Of Southern California High throughput method of DNA methylation haplotyping
EP2135080A4 (en) * 2007-03-08 2010-12-01 Switchgear Genomics FUNCTIONAL NETWORKS FOR THE CHARACTERIZATION OF TREATMENT OF REGULATORY ELEMENTS IN NON-TRANSLATED REGIONS OF GENES
ES2453108T3 (es) * 2007-08-06 2014-04-04 Orion Genomics, Llc Nuevos polimorfismos de un único nucleótido y combinaciones de polimorfismos nuevos y conocidos para determinar la expresión específica de alelo del gen IGF2

Also Published As

Publication number Publication date
WO2010093820A3 (en) 2010-10-14
JP2012517242A (ja) 2012-08-02
EP2396429A4 (en) 2012-10-31
JP2015180207A (ja) 2015-10-15
US20100286926A1 (en) 2010-11-11
WO2010093820A2 (en) 2010-08-19
EP2955234A1 (en) 2015-12-16
AU2010213727A1 (en) 2011-09-29
CA2751758A1 (en) 2010-08-19
EP2396429B1 (en) 2015-05-27
EP2396429A2 (en) 2011-12-21
JP5748672B2 (ja) 2015-07-15

Similar Documents

Publication Publication Date Title
ES2543684T3 (es) Nuevos polimorfismos de un único nucleótido y combinaciones de polimorfismos nuevos y conocidos para determinar la expresión específica de alelo del gen IGF2
ES2544265T3 (es) Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2
US8021845B2 (en) Probes for detecting obesity gene
Chang et al. Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer
US20070275386A1 (en) Polymorphisms in the Epidermal Growth Factor Receptor Gene Promoter
Cotton et al. Single nucleotide polymorphism in RECQL and survival in resectable pancreatic adenocarcinoma
KR101309887B1 (ko) 위암 감수성 진단용 lox 유전자 snp 및 이를 이용한 위암 감수성 진단방법
KR20150092937A (ko) 한국인의 고혈압 예측용 snp 마커
KR101092580B1 (ko) 위암 감수성 예측용 vcan 다형성 마커 및 이를 이용한위암 감수성 예측 방법
CN111705121A (zh) 一种全预混cyp2c9和vkorc1多重pcr基因多态性检测试剂盒和方法
Haaland Assessment of field effect in the cancerous prostate
AU2014202560A1 (en) Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene