ES2537290T3 - Sensor desechable de volumen submicrolitro - Google Patents

Sensor desechable de volumen submicrolitro Download PDF

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Publication number
ES2537290T3
ES2537290T3 ES00936445.6T ES00936445T ES2537290T3 ES 2537290 T3 ES2537290 T3 ES 2537290T3 ES 00936445 T ES00936445 T ES 00936445T ES 2537290 T3 ES2537290 T3 ES 2537290T3
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strip
enclosed channel
electrode
laminated
base layer
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ES00936445.6T
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Handani Winarta
Xiaohua Cai
Fung Seto
Chung Chang Young
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Nova Biomedical Corp
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Nova Biomedical Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Tira de electrodo desechable (10) para someter a prueba una muestra fluida que comprende: una tira laminada (100) que tiene un primer extremo de tira (110) y un segundo extremo de tira (120), comprendiendo dicha tira laminada (100) una capa de base (20) que tiene una capa conductora (21) dispuesta sobre la misma y trazada para delinear tres trayectorias de electrodo (22, 23, 24), una capa de formación de canal (30) portada sobre dicha capa de base, y una cubierta (40), en la que dicha tira laminada tiene un orificio de ventilación (42) en una superficie superior de dicha tira laminada (100) y separada de dicho primer extremo de tira (110); un canal encerrado (112) entre dicho primer extremo de tira (110) y dicho orificio de ventilación (42), en la que el volumen de dicho canal encerrado es inferior a un microlitro, y dicho canal encerrado contiene un electrodo de trabajo (W), un pseudoelectrodo de trabajo (W0) y un electrodo de referencia (R), siendo la disposición de los electrodos W, W0 y R dentro de dicho canal encerrado, R-W-W0 en la dirección desde dicho extremo de la primera tira (110) hasta dicho orificio de ventilación (42); una matriz de reactivos (50), que contiene al menos una enzima, un mediador redox, un estabilizador, un aglutinante, un tensioactivo y un tampón, dispuesta sobre dicha capa de base en dicho canal encerrado, en la que dicho estabilizador es polialquilenglicol, dicho aglutinante es metilcelulosa, dicho tensioactivo es toctilfenoxipolietoxietanol y dicho tampón es un tampón citrato; contactos conductores en dicho segundo extremo de tira y aislados de dicho canal encerrado.

Description

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Claims (1)

  1. imagen1
ES00936445.6T 1999-06-02 2000-05-31 Sensor desechable de volumen submicrolitro Expired - Lifetime ES2537290T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US324493 1999-06-02
US09/324,493 US6258229B1 (en) 1999-06-02 1999-06-02 Disposable sub-microliter volume sensor and method of making
PCT/US2000/015106 WO2000073778A1 (en) 1999-06-02 2000-05-31 Disposable sub-microliter volume sensor and method of making

Publications (1)

Publication Number Publication Date
ES2537290T3 true ES2537290T3 (es) 2015-06-05

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ES00936445.6T Expired - Lifetime ES2537290T3 (es) 1999-06-02 2000-05-31 Sensor desechable de volumen submicrolitro

Country Status (7)

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US (1) US6258229B1 (es)
EP (1) EP1181539B1 (es)
JP (1) JP2003501626A (es)
AU (1) AU5176000A (es)
CA (1) CA2375089C (es)
ES (1) ES2537290T3 (es)
WO (1) WO2000073778A1 (es)

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