ES2534358T3 - Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades - Google Patents
Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades Download PDFInfo
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- ES2534358T3 ES2534358T3 ES10824026.8T ES10824026T ES2534358T3 ES 2534358 T3 ES2534358 T3 ES 2534358T3 ES 10824026 T ES10824026 T ES 10824026T ES 2534358 T3 ES2534358 T3 ES 2534358T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/08—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
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| US25093609P | 2009-10-13 | 2009-10-13 | |
| US250936P | 2009-10-13 | ||
| PCT/US2010/052514 WO2011047055A2 (en) | 2009-10-13 | 2010-10-13 | Novel mek inhibitors, useful in the treatment of diseases |
Publications (1)
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|---|---|
| ES2534358T3 true ES2534358T3 (es) | 2015-04-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| ES10824026.8T Active ES2534358T3 (es) | 2009-10-13 | 2010-10-13 | Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9034861B2 (https=) |
| EP (1) | EP2488507B1 (https=) |
| JP (1) | JP5892612B2 (https=) |
| KR (1) | KR20120094165A (https=) |
| CN (1) | CN102666512B (https=) |
| AU (1) | AU2010306830C1 (https=) |
| BR (1) | BR112012008599A2 (https=) |
| CA (1) | CA2814617C (https=) |
| ES (1) | ES2534358T3 (https=) |
| WO (1) | WO2011047055A2 (https=) |
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| WO2017033113A1 (en) | 2015-08-21 | 2017-03-02 | Acerta Pharma B.V. | Therapeutic combinations of a mek inhibitor and a btk inhibitor |
| US11559544B2 (en) | 2017-08-23 | 2023-01-24 | Cell Receptor AG | Combination of a MAPK/ERK pathway inhibitor and a glycosaminoglycan for the treatment of cancer |
| EA202192575A1 (ru) | 2019-03-21 | 2022-01-14 | Онксео | Соединения dbait в сочетании с ингибиторами киназ для лечения рака |
| CN114761006A (zh) | 2019-11-08 | 2022-07-15 | Inserm(法国国家健康医学研究院) | 对激酶抑制剂产生耐药性的癌症的治疗方法 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| AU2021401282A1 (en) * | 2020-12-16 | 2023-07-13 | Mosaica Medicines, Inc. | Kinase inhibitors and uses thereof |
| US12280055B2 (en) | 2021-05-27 | 2025-04-22 | Mirati Therapeutics, Inc. | Combination therapies |
| WO2025073765A1 (en) | 2023-10-03 | 2025-04-10 | Institut National de la Santé et de la Recherche Médicale | Methods of prognosis and treatment of patients suffering from melanoma |
| WO2025147503A1 (en) | 2024-01-05 | 2025-07-10 | Pasithea Therapeutics Corp. | 10,11-difluoro-12-((2-fluoro-4-iodophenyl)amino)-5,6-dihydroxy-4,5,6,7-tetrahydro-1h-spiro[benzo[b][1,5,4]oxathiazecine-3,1'-cyclopropane] 2,2-dioxide stereoisomers, and compositions comprising and methods of using the same |
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2010
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- 2010-10-13 BR BR112012008599A patent/BR112012008599A2/pt not_active IP Right Cessation
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| US20120208859A1 (en) | 2012-08-16 |
| US9034861B2 (en) | 2015-05-19 |
| CN102666512A (zh) | 2012-09-12 |
| WO2011047055A3 (en) | 2011-08-18 |
| EP2488507B1 (en) | 2014-12-17 |
| EP2488507A4 (en) | 2013-05-01 |
| AU2010306830A1 (en) | 2012-05-31 |
| CA2814617A1 (en) | 2011-04-21 |
| KR20120094165A (ko) | 2012-08-23 |
| BR112012008599A2 (pt) | 2019-09-24 |
| WO2011047055A2 (en) | 2011-04-21 |
| WO2011047055A8 (en) | 2012-05-24 |
| JP2013507453A (ja) | 2013-03-04 |
| AU2010306830B2 (en) | 2014-11-06 |
| EP2488507A2 (en) | 2012-08-22 |
| CN102666512B (zh) | 2014-11-26 |
| CA2814617C (en) | 2017-12-19 |
| AU2010306830C1 (en) | 2015-05-28 |
| JP5892612B2 (ja) | 2016-03-23 |
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