ES2534358T3 - Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades - Google Patents
Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades Download PDFInfo
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- ES2534358T3 ES2534358T3 ES10824026.8T ES10824026T ES2534358T3 ES 2534358 T3 ES2534358 T3 ES 2534358T3 ES 10824026 T ES10824026 T ES 10824026T ES 2534358 T3 ES2534358 T3 ES 2534358T3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
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| US25093609P | 2009-10-13 | 2009-10-13 | |
| US250936P | 2009-10-13 | ||
| PCT/US2010/052514 WO2011047055A2 (en) | 2009-10-13 | 2010-10-13 | Novel mek inhibitors, useful in the treatment of diseases |
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| ES2534358T3 true ES2534358T3 (es) | 2015-04-21 |
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| ES10824026.8T Active ES2534358T3 (es) | 2009-10-13 | 2010-10-13 | Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades |
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| US20190008859A1 (en) | 2015-08-21 | 2019-01-10 | Acerta Pharma B.V. | Therapeutic Combinations of a MEK Inhibitor and a BTK Inhibitor |
| CA3072856A1 (en) | 2017-08-23 | 2019-02-28 | Cell Receptor AG | Combination of a mapk/erk pathway inhibitor and a glycosaminoglycan for the treatment of cancer |
| CA3129665A1 (en) | 2019-03-21 | 2020-09-24 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| KR20220098759A (ko) | 2019-11-08 | 2022-07-12 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 키나제 억제제에 대해 내성을 획득한 암의 치료 방법 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| EP4263501A1 (en) * | 2020-12-16 | 2023-10-25 | ABM Therapeutics Corporation | Kinase inhibitors and uses thereof |
| JP2024521788A (ja) | 2021-05-27 | 2024-06-04 | ミラティ セラピューティクス， インコーポレイテッド | 併用療法 |
| CN118973580A (zh) | 2022-04-08 | 2024-11-15 | 米拉蒂治疗股份有限公司 | 包含sos1抑制剂和mek抑制剂的组合疗法 |
| EP4788839A1 (en) | 2023-10-03 | 2026-08-12 | Institut National de la Santé et de la Recherche Médicale | Methods of prognosis and treatment of patients suffering from melanoma |
| IL330382A (en) | 2024-01-05 | 2026-08-01 | Pasithea Therapeutics Corp | Stereoisomers of 10,11-difluoro-12-((2-fluoro-4-iodophenyl)amino)-5,6-dihydroxy-4,5,6,7-tetrahydro-1H-spiro[benzo[b][1,5,4]oxathiazepine-3,1'-cyclopropane] 2,2-dioxide, as well as compositions containing them and methods of using them |
| IL330371A (en) | 2024-01-05 | 2026-08-01 | Pasithea Therapeutics Corp | Solid forms containing (5R,6S)-10,11-difluoro-12-((2-fluoro-4-iodophenyl)amino)-5,6-dihydroxy-4,5,6,7-tetrahydro-1H-spiro[benzo[b][1,5,4]oxathiazepine-3,1'-cyclopropane] 2,2-dioxide, as well as compositions containing the same and methods of using the same |
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| CA2814617A1 (en) | 2011-04-21 |
| WO2011047055A3 (en) | 2011-08-18 |
| AU2010306830B2 (en) | 2014-11-06 |
| EP2488507A2 (en) | 2012-08-22 |
| CA2814617C (en) | 2017-12-19 |
| WO2011047055A2 (en) | 2011-04-21 |
| CN102666512B (zh) | 2014-11-26 |
| EP2488507B1 (en) | 2014-12-17 |
| WO2011047055A8 (en) | 2012-05-24 |
| CN102666512A (zh) | 2012-09-12 |
| EP2488507A4 (en) | 2013-05-01 |
| KR20120094165A (ko) | 2012-08-23 |
| US20120208859A1 (en) | 2012-08-16 |
| AU2010306830A1 (en) | 2012-05-31 |
| BR112012008599A2 (pt) | 2019-09-24 |
| JP5892612B2 (ja) | 2016-03-23 |
| US9034861B2 (en) | 2015-05-19 |
| AU2010306830C1 (en) | 2015-05-28 |
| JP2013507453A (ja) | 2013-03-04 |
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