ES251430A1 - Procedimiento para la obtenciën de nuevos derivados fosforosos de indol - Google Patents
Procedimiento para la obtenciën de nuevos derivados fosforosos de indolInfo
- Publication number
- ES251430A1 ES251430A1 ES0251430A ES251430A ES251430A1 ES 251430 A1 ES251430 A1 ES 251430A1 ES 0251430 A ES0251430 A ES 0251430A ES 251430 A ES251430 A ES 251430A ES 251430 A1 ES251430 A1 ES 251430A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compounds
- alkyl
- nitrogen atom
- addition salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 229910052698 phosphorus Inorganic materials 0.000 title 1
- 239000011574 phosphorus Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000003386 piperidinyl group Chemical group 0.000 abstract 2
- OHHYMKDBKJPILO-UHFFFAOYSA-N 3-[2-(diethylamino)ethyl]-1h-indol-4-ol Chemical compound C1=CC(O)=C2C(CCN(CC)CC)=CNC2=C1 OHHYMKDBKJPILO-UHFFFAOYSA-N 0.000 abstract 1
- NLMQHXUGJIAKTH-UHFFFAOYSA-N 4-hydroxyindole Chemical class OC1=CC=CC2=C1C=CN2 NLMQHXUGJIAKTH-UHFFFAOYSA-N 0.000 abstract 1
- HDFFVHSMHLDSLO-UHFFFAOYSA-N Dibenzyl phosphate Chemical class C=1C=CC=CC=1COP(=O)(O)OCC1=CC=CC=C1 HDFFVHSMHLDSLO-UHFFFAOYSA-N 0.000 abstract 1
- SMVXYBYTGKEHCS-UHFFFAOYSA-N [benzyl(chloro)phosphoryl]methylbenzene Chemical compound C=1C=CC=CC=1CP(=O)(Cl)CC1=CC=CC=C1 SMVXYBYTGKEHCS-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- SPCIYGNTAMCTRO-UHFFFAOYSA-N psilocin Chemical compound C1=CC(O)=C2C(CCN(C)C)=CNC2=C1 SPCIYGNTAMCTRO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6387558A CH370409A (de) | 1958-09-12 | 1958-09-12 | Verfahren zur Herstellung von neuen, phosphorhaltigen Indol-Derivaten |
| CH6842459A CH375359A (de) | 1959-01-16 | 1959-01-16 | Verfahren zur Herstellung von neuen, phosphorhaltigen Indol-Derivaten |
| CH7074259 | 1959-03-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES251430A1 true ES251430A1 (es) | 1960-04-01 |
Family
ID=27178509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0251430A Expired ES251430A1 (es) | 1958-09-12 | 1959-08-13 | Procedimiento para la obtenciën de nuevos derivados fosforosos de indol |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE582353A (en, 2012) |
| DE (1) | DE1211645B (en, 2012) |
| ES (1) | ES251430A1 (en, 2012) |
| FR (1) | FR1311106A (en, 2012) |
| GB (1) | GB912714A (en, 2012) |
| LU (1) | LU37646A1 (en, 2012) |
| NL (2) | NL243249A (en, 2012) |
| OA (1) | OA01253A (en, 2012) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| EP3955918A1 (en) | 2019-04-17 | 2022-02-23 | COMPASS Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
| JP2023526856A (ja) | 2020-05-19 | 2023-06-23 | サイビン アイアールエル リミテッド | 重水素化トリプタミン誘導体および使用方法 |
| CA3181092A1 (en) | 2020-06-30 | 2022-01-06 | Nathan Bryson | Tryptamine prodrugs |
| EP4486448A1 (en) | 2022-03-04 | 2025-01-08 | Reset Pharmaceuticals, Inc. | Co-crystals or salts comprising psilocin |
-
0
- BE BE582353D patent/BE582353A/xx unknown
- NL NL121067D patent/NL121067C/xx active
- NL NL243249D patent/NL243249A/xx unknown
- LU LU37646D patent/LU37646A1/xx unknown
-
1959
- 1959-08-13 ES ES0251430A patent/ES251430A1/es not_active Expired
- 1959-08-24 GB GB28884/59A patent/GB912714A/en not_active Expired
- 1959-09-08 DE DES64818A patent/DE1211645B/de active Pending
- 1959-09-10 FR FR804443A patent/FR1311106A/fr not_active Expired
-
1964
- 1964-12-31 OA OA51500A patent/OA01253A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1211645B (de) | 1966-03-03 |
| OA01253A (fr) | 1969-01-25 |
| LU37646A1 (en, 2012) | |
| GB912714A (en) | 1962-12-12 |
| BE582353A (en, 2012) | |
| NL243249A (en, 2012) | |
| FR1311106A (fr) | 1962-12-07 |
| NL121067C (en, 2012) |
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