ES2465715A1 - Péptido, péptido magnético y método para detectar la enfermedad celíaca - Google Patents

Péptido, péptido magnético y método para detectar la enfermedad celíaca Download PDF

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Publication number
ES2465715A1
ES2465715A1 ES201430198A ES201430198A ES2465715A1 ES 2465715 A1 ES2465715 A1 ES 2465715A1 ES 201430198 A ES201430198 A ES 201430198A ES 201430198 A ES201430198 A ES 201430198A ES 2465715 A1 ES2465715 A1 ES 2465715A1
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ES
Spain
Prior art keywords
peptide
magnetic
celiac disease
translation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201430198A
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English (en)
Other versions
ES2465715B1 (es
Inventor
María Isabel PIVIDORI GURGO
Vanessa Silvina KERGARAVAT
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitat Autonoma de Barcelona UAB
Original Assignee
Universitat Autonoma de Barcelona UAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitat Autonoma de Barcelona UAB filed Critical Universitat Autonoma de Barcelona UAB
Priority to ES201430198A priority Critical patent/ES2465715B1/es
Publication of ES2465715A1 publication Critical patent/ES2465715A1/es
Priority to CA2939476A priority patent/CA2939476C/en
Priority to PCT/ES2015/070097 priority patent/WO2015121526A1/es
Priority to EP15749357.8A priority patent/EP3106466B1/en
Priority to US15/118,516 priority patent/US10156565B2/en
Application granted granted Critical
Publication of ES2465715B1 publication Critical patent/ES2465715B1/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/415—Assays involving biological materials from specific organisms or of a specific nature from plants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un péptido, a un péptido magnético y a un método para detectar la enfermedad celíaca. También se refiere a un péptido deaminado que se emplea para preparar dicho péptido magnético, y al empleo de ambos para la detección de la enfermedad celíaca. Dicho péptido deaminado comprende una cola de histidinas y está unido a un complejo magnético particulado. También se refiere a un inmunosensor que comprende dicho péptido magnético, a un método apropiado para detectar la enfermedad celíaca basado en un immunoensayo magnético y a un kit que comprende dicho péptido magnético.
ES201430198A 2014-02-14 2014-02-14 Péptido, péptido magnético y método para detectar la enfermedad celíaca Active ES2465715B1 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES201430198A ES2465715B1 (es) 2014-02-14 2014-02-14 Péptido, péptido magnético y método para detectar la enfermedad celíaca
CA2939476A CA2939476C (en) 2014-02-14 2015-02-16 Peptides, magnetic peptides, immunosensors and method for detecting celiac disease
PCT/ES2015/070097 WO2015121526A1 (es) 2014-02-14 2015-02-16 Péptido, péptido magnético y método para detectar la enfermedad celíaca
EP15749357.8A EP3106466B1 (en) 2014-02-14 2015-02-16 Peptide, magnetic peptide and method for detecting celiac disease
US15/118,516 US10156565B2 (en) 2014-02-14 2015-02-16 Peptide, magnetic peptide and method for detecting celiac disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201430198A ES2465715B1 (es) 2014-02-14 2014-02-14 Péptido, péptido magnético y método para detectar la enfermedad celíaca

Publications (2)

Publication Number Publication Date
ES2465715A1 true ES2465715A1 (es) 2014-06-06
ES2465715B1 ES2465715B1 (es) 2015-03-18

Family

ID=50843176

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201430198A Active ES2465715B1 (es) 2014-02-14 2014-02-14 Péptido, péptido magnético y método para detectar la enfermedad celíaca

Country Status (5)

Country Link
US (1) US10156565B2 (es)
EP (1) EP3106466B1 (es)
CA (1) CA2939476C (es)
ES (1) ES2465715B1 (es)
WO (1) WO2015121526A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201806385PA (en) * 2016-01-27 2018-08-30 Massachusetts Gen Hospital Magnetic electrochemical sensing
EP3922991A1 (en) * 2020-06-10 2021-12-15 PreOmics GmbH Dispersion using a moving magnet

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089933A1 (en) * 2004-03-17 2005-09-29 Dynal Biotech Asa Improvements in polymer particles
US20090311727A1 (en) * 2008-04-21 2009-12-17 Bio-Rad Laboratories, Inc. Recombinant deamidated gliadin antigen
US20130109034A1 (en) * 2010-03-10 2013-05-02 IMMCO Diagnostics, Inc. Compositions and Methods for Determining Celiac Disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155316C (no) 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
US5962641A (en) 1996-08-16 1999-10-05 Clontech Laboratories, Inc. Method for purification of recombinant proteins
CA2369293C (en) 1999-04-09 2010-06-08 Dynal Particles As Process for the preparation of monodisperse polymer particles
WO2005000441A2 (en) * 2003-06-27 2005-01-06 Dynal Biotech Asa Conjugates of magnetic polymer particles and carboxymethylated aspartic acid
US20080038760A1 (en) 2004-06-08 2008-02-14 Method For Decting Anti-Transglutaminase Antibodies Method for Detecting Anti-Transglutaminase Antibodies
DE102007025291A1 (de) * 2007-05-30 2008-12-04 Euroimmun Ag Verfahren und Immunabsorbentien zur spezifischen Detektion und Absorption Zöliakie- und Dermatitis herpetiformis assoziierter Antikörper
ES2688268T3 (es) * 2011-12-05 2018-10-31 Bio-Rad Laboratories, Inc. Antígeno de gliadina desamidada recombinante
ES2407055B1 (es) 2011-12-07 2014-04-16 Universidad Pablo De Olavide Empleo de anticuerpos anti-beta-lactoglobulina en el diagnóstico y seguimiento de la enfermedad celíaca

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089933A1 (en) * 2004-03-17 2005-09-29 Dynal Biotech Asa Improvements in polymer particles
US20090311727A1 (en) * 2008-04-21 2009-12-17 Bio-Rad Laboratories, Inc. Recombinant deamidated gliadin antigen
US20130109034A1 (en) * 2010-03-10 2013-05-02 IMMCO Diagnostics, Inc. Compositions and Methods for Determining Celiac Disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LAUBE T. et al. Magneto immunosensor for gliadin detection in gluten free food-stuff: Towards food safety for celiac patients. Biosensors and Bioelectronics. 2011, Vol. 27, páginas: 46-52, todo el documento. *
SCHWERTZ E. et al. Serologic Assay Based on Gliadin- Related Nonapeptides as a Highly Sensitive and Specific Diagnostic Aid in Celiac Disease. Clinical Chemistry. 2004, Vol. 50(12), páginas: 2370-2375, todo el documento.SCHWERTZ E. et al. Serologic Assay Based on Gliadin- Related Nonapeptides as a Highly Sensitive and Specific Diagnostic Aid in Celiac Disease. Clinical Chemistry. 2004, Vol. 50(12), páginas: 2370-2375, todo el documento. *

Also Published As

Publication number Publication date
US10156565B2 (en) 2018-12-18
EP3106466B1 (en) 2019-04-10
ES2465715B1 (es) 2015-03-18
CA2939476A1 (en) 2015-08-20
WO2015121526A1 (es) 2015-08-20
EP3106466A4 (en) 2017-09-06
CA2939476C (en) 2021-06-22
EP3106466A1 (en) 2016-12-21
US20170153233A1 (en) 2017-06-01

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