ES244420A1 - Procedure for the preparation of new alpha-aril-omega-amido secondary-alkaline acids and their derivatives (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the preparation of new alpha-aril-omega-amido secondary-alkaline acids and their derivatives (Machine-translation by Google Translate, not legally binding)
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Novartis AG
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JR Geigy AG
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Priority to ES0244420ApriorityCriticalpatent/ES244420A1/en
Publication of ES244420A1publicationCriticalpatent/ES244420A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Process for the preparation of new secondary alpha-aryl-omega-amino-alkanic acids, characterized in that compounds of the general formula are prepared ** (See formula) ** as well as its salts with acids, in which they mean, R1 hydrogen, or a low molecular weight alkyl group, R2 hydrogen, or the group COOR1, R3, R4 and R5 hydrogen, or a low molecular weight alkyl group, Ar a phenyl group, unsubstituted or substituted, to which effect the substituents may be halogen, methyl, methoxy, benzyloxy or hydroxy groups, and n 0, or a small whole number, the condition being valid that at least one of the groups R1, R2 and R3 should not be hydrogen if n = 0, by reduction of oximes of the general formula ** (See formula) ** wherein R2 ', R4, R5 and n have the meaning indicated above, and X means the cyano group -CN, or the group -COO-R1', particularly with the aid of palladium carbon as a catalyst and, if necessary, subsequent hydrolysis of the cyano group optionally present, as well as, if desired, alkylation and esterification. (Machine-translation by Google Translate, not legally binding)
ES0244420A1958-09-291958-09-29Procedure for the preparation of new alpha-aril-omega-amido secondary-alkaline acids and their derivatives (Machine-translation by Google Translate, not legally binding)
ExpiredES244420A1
(en)
Procedure for the preparation of new alpha-aril-omega-amido secondary-alkaline acids and their derivatives (Machine-translation by Google Translate, not legally binding)
Procedure for the preparation of new alpha-aril-omega-amido secondary-alkaline acids and their derivatives (Machine-translation by Google Translate, not legally binding)
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