ES2434039T3 - Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación - Google Patents

Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación Download PDF

Info

Publication number
ES2434039T3
ES2434039T3 ES07766836T ES07766836T ES2434039T3 ES 2434039 T3 ES2434039 T3 ES 2434039T3 ES 07766836 T ES07766836 T ES 07766836T ES 07766836 T ES07766836 T ES 07766836T ES 2434039 T3 ES2434039 T3 ES 2434039T3
Authority
ES
Spain
Prior art keywords
ccl2
lymphocytes
diseases
autoimmune
inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07766836T
Other languages
English (en)
Spanish (es)
Inventor
Liat Flaishon
Idit Shachar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of ES2434039T3 publication Critical patent/ES2434039T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES07766836T 2006-07-24 2007-06-28 Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación Active ES2434039T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83260006P 2006-07-24 2006-07-24
US832600P 2006-07-24
PCT/IL2007/000806 WO2008012796A2 (en) 2006-07-24 2007-06-28 Pharmaceutical compositions comprising ccl2 and use of same for the treatment of inflammation

Publications (1)

Publication Number Publication Date
ES2434039T3 true ES2434039T3 (es) 2013-12-13

Family

ID=38981868

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07766836T Active ES2434039T3 (es) 2006-07-24 2007-06-28 Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación

Country Status (7)

Country Link
US (2) US7919077B2 (OSRAM)
EP (1) EP2056857B1 (OSRAM)
JP (1) JP2009544690A (OSRAM)
AU (1) AU2007278054B2 (OSRAM)
CA (1) CA2658719A1 (OSRAM)
ES (1) ES2434039T3 (OSRAM)
WO (1) WO2008012796A2 (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7919077B2 (en) * 2006-07-24 2011-04-05 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising CCL2 and use of same for the treatment of inflammation
US20120070449A1 (en) 2009-05-28 2012-03-22 Yeda Research And Development Co. Ltd. Methods of treating inflammation
CN101829075B (zh) * 2010-04-27 2011-07-20 中国人民解放军第三军医大学第一附属医院 苦柯胺a和苦柯胺b的用途
WO2012131680A2 (en) 2011-03-28 2012-10-04 Yeda Research And Development Co. Ltd. Compositions and methods for treating inflammation
WO2015191783A2 (en) 2014-06-10 2015-12-17 Abbvie Inc. Biomarkers for inflammatory disease and methods of using same
WO2016176583A1 (en) * 2015-04-29 2016-11-03 Sanford-Burnham Medical Research Institute Modulation of immune response using btla agonist antibodies
WO2017062493A1 (en) 2015-10-05 2017-04-13 Board Of Regents, The University Of Texas System Micro-and nano-device for cartilage injury detection and treatment
KR102066149B1 (ko) * 2018-08-17 2020-01-14 고려대학교 산학협력단 Ccl2를 유효성분으로 포함하는 임신촉진용 조성물
KR102154235B1 (ko) * 2019-02-11 2020-09-09 고려대학교 산학협력단 Ccl2를 유효성분으로 포함하는 산유량 증가용 조성물, 및 유방염 예방 또는 치료용 약학적 조성물

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05271093A (ja) * 1992-03-30 1993-10-19 Toray Ind Inc 血管内皮細胞増殖剤
US6184235B1 (en) * 1996-08-14 2001-02-06 Warner-Lambert Company 2-phenyl benzimidazole derivatives as MCP-1 antagonists
US6316420B1 (en) * 1998-07-28 2001-11-13 Technion Research And Development Foundation Ltd. DNA cytokine vaccines and use of same for protective immunity against multiple sclerosis
GB0016138D0 (en) * 2000-06-30 2000-08-23 Novartis Ag Organic compounds
ATE323772T1 (de) * 2000-07-06 2006-05-15 Deutsches Krebsforsch Regulatorische sequenzen des humanen mcp-1 gens
US7601692B2 (en) * 2000-11-28 2009-10-13 Compugen Ltd. MCP-1 splice variants and methods of using same
TWI245761B (en) * 2001-03-01 2005-12-21 Telik Inc Antagonists of MCP-1 function and methods of use thereof
UA87979C2 (ru) * 2002-08-19 2009-09-10 Астразенека Аб Человеческое моноклональное антитело, которое нейтрализует моноцитарный хемоатрактантный белок (мср-1)
JP4601936B2 (ja) * 2002-10-29 2010-12-22 株式会社ミノファーゲン製薬 Mcp−1産生抑制のための薬学的組成物
AR046594A1 (es) * 2003-10-16 2005-12-14 Applied Research Systems Usos terapeuticos de variantes de quemoquina
EP1684703A4 (en) * 2003-11-05 2008-10-01 Centocor Inc METHODS AND COMPOSITIONS FOR TREATING PATHOLOGIES ASSOCIATED WITH MCP-1
CN101443357A (zh) * 2005-08-12 2009-05-27 先灵公司 Mcp1融合物
JP2010521413A (ja) * 2006-03-16 2010-06-24 プロタゴニスツ リミテッド 免疫系機能を改変するためのサイトカインとサイトカイン受容体の組合せ
US7919077B2 (en) * 2006-07-24 2011-04-05 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising CCL2 and use of same for the treatment of inflammation

Also Published As

Publication number Publication date
AU2007278054B2 (en) 2012-11-22
US20090239799A1 (en) 2009-09-24
WO2008012796A2 (en) 2008-01-31
WO2008012796A3 (en) 2009-04-09
EP2056857A2 (en) 2009-05-13
EP2056857B1 (en) 2013-08-21
US7919077B2 (en) 2011-04-05
JP2009544690A (ja) 2009-12-17
US20110165116A1 (en) 2011-07-07
EP2056857A4 (en) 2011-02-16
AU2007278054A1 (en) 2008-01-31
CA2658719A1 (en) 2008-01-31

Similar Documents

Publication Publication Date Title
ES2434039T3 (es) Composiciones farmacéuticas que comprenden ccl2 para su uso en el tratamiento de la inflamación
US7354575B2 (en) Method and pharmaceutical composition for treating inflammation
Ambler et al. Vascular damage in systemic lupus erythematosus
Gerdes et al. Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis
Firestein et al. Apoptosis in rheumatoid arthritis synovium.
Karmouty-Quintana et al. The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease
IL194987A (en) Use of PIF peptide to produce a drug to regulate the immune system
Berghmans et al. Rescue from acute neuroinflammation by pharmacological chemokine-mediated deviation of leukocytes
MacDonnell et al. Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development
Huang et al. Inhibitory effects of endogenous and exogenous interferon‐γ on bronchial hyperresponsiveness, allergic inflammation and T‐helper 2 cytokines in Brown–Norway rats
Lutje et al. Trypanosoma congolense: proliferative responses and interleukin production in lymph node cells of infected cattle
Li et al. Anaphylatoxins in organ transplantation
AU2008253667A1 (en) Treatment of allergic disease with immunomodulator compounds
US12239650B2 (en) Compounds for treating and preventing net associated complications
P Sarapultsev et al. Effect of a new class of compounds of the group of substituted 5R1, 6H2-1, 3, 4-thiadiazine-2-amines on the inflammatory and cytokine response in experimental myocardial infarction
JP2020511418A (ja) Ilc2細胞に関連する疾患を処置する方法
CN116196423B (zh) 趋化因子ccl17作为治疗靶点在制备抑制或延缓衰老的产品中的应用
ODonnell et al. PS-B06-8: EXPLORING THE ROLE OF NECROPTOSIS IN HYPERTENSION
Omert et al. A role of neutrophils in the down-regulation of IL-6 and CD14 following hemorrhagic shock
CN114470196B (zh) CCL3/CCR4中和抗体、NF-κB抑制剂在制备NEC治疗药物中的用途
Wang et al. General Control Nonderepressible 2 Promotes M2 Macrophages Polarization and Renal Function After Sepsis-Induced Renal Injury
RU2457789C2 (ru) Способ иммунотерапии гнойного риносинусита
Kono et al. Nafamostat mesylate therapy for systemic lupus erythematosus with nephrotic syndrome: a case report
CN119701016A (zh) 促进march2基因表达的试剂在制备治疗主动脉瘤/夹层药物中的应用
Kiani et al. Case Report Severe Pulmonary Hypertension as Initial Presentation of SLE: A Case Report and Literature Review