ES2433011T3 - Receptor TWEAK - Google Patents
Receptor TWEAK Download PDFInfo
- Publication number
- ES2433011T3 ES2433011T3 ES00990269T ES00990269T ES2433011T3 ES 2433011 T3 ES2433011 T3 ES 2433011T3 ES 00990269 T ES00990269 T ES 00990269T ES 00990269 T ES00990269 T ES 00990269T ES 2433011 T3 ES2433011 T3 ES 2433011T3
- Authority
- ES
- Spain
- Prior art keywords
- tweak
- tweakr
- receptor
- angiogenesis
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17287899P | 1999-12-20 | 1999-12-20 | |
| US172878P | 1999-12-20 | ||
| US20334700P | 2000-05-10 | 2000-05-10 | |
| US203347P | 2000-05-10 | ||
| PCT/US2000/034755 WO2001045730A2 (en) | 1999-12-20 | 2000-12-19 | Tweak receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2433011T3 true ES2433011T3 (es) | 2013-12-05 |
Family
ID=26868552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00990269T Expired - Lifetime ES2433011T3 (es) | 1999-12-20 | 2000-12-19 | Receptor TWEAK |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6824773B2 (enExample) |
| EP (3) | EP2298333A3 (enExample) |
| JP (1) | JP5148795B2 (enExample) |
| AU (1) | AU782067B2 (enExample) |
| CA (1) | CA2394015C (enExample) |
| ES (1) | ES2433011T3 (enExample) |
| IL (1) | IL149922A (enExample) |
| NZ (1) | NZ520171A (enExample) |
| WO (1) | WO2001045730A2 (enExample) |
Families Citing this family (43)
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| US7129061B1 (en) * | 1996-08-07 | 2006-10-31 | Biogen Idec Ma Inc. | Tumor necrosis factor related ligand |
| DK1015477T3 (da) | 1997-05-30 | 2011-02-07 | Human Genome Sciences Inc | 32 humane sekreterede proteiner |
| US7001992B2 (en) | 1997-05-30 | 2006-02-21 | Human Genome Sciences, Inc. | Antibodies to secreted protein HEMCM42 |
| AU2507700A (en) | 1999-01-15 | 2000-08-01 | Biogen, Inc. | Antagonists of tweak and of tweak receptor and their use to treat immunological disorders |
| US6727225B2 (en) | 1999-12-20 | 2004-04-27 | Immunex Corporation | TWEAK receptor |
| US7495086B2 (en) * | 1999-12-20 | 2009-02-24 | Immunex Corporation | TWEAK receptor |
| US6943146B2 (en) | 2000-05-08 | 2005-09-13 | Biogen Idec Ma Inc. | Method for promoting neovascularization |
| CA2422095A1 (en) * | 2000-09-14 | 2002-03-21 | Biogen, Inc. | Tweak receptor agonists as anti-angiogenic agents |
| US7208151B2 (en) * | 2001-09-12 | 2007-04-24 | Biogen Idec Ma Inc. | Tweak receptor agonists as anti-angiogenic agents |
| KR100801388B1 (ko) * | 2002-01-02 | 2008-02-05 | 제넨테크, 인크. | 종양의 진단 및 치료 방법 및 이를 위한 조성물 |
| SI1997512T1 (sl) * | 2002-04-09 | 2014-03-31 | Biogen Idec Ma Inc. | Postopki za zdravljenje stanj, povezanih s TWEAK-om |
| ATE364050T1 (de) * | 2003-07-24 | 2007-06-15 | Amgen Inc | Zusammensetzungen und verfahren, die multimere und oligomere lösliche fragmente des tweak- rezeptors betreffen |
| WO2005053728A2 (de) * | 2003-12-01 | 2005-06-16 | Xantos Biomedicine Ag | Mit adipositas assoziierte proteine und deren verwendung in therapie und diagnostik |
| EP1709976A4 (en) * | 2003-12-26 | 2007-10-17 | Toshio Hirano | EMT-INDUCING MEDIUM |
| US7790447B2 (en) * | 2004-07-27 | 2010-09-07 | Riken | Vector expressing n-deacetylase/n-sulfotransferase 2 |
| CA2596412A1 (en) * | 2005-02-03 | 2006-12-21 | Coda Therapeutics Limited | Anti-connexin compounds and uses thereof |
| WO2006088890A2 (en) * | 2005-02-17 | 2006-08-24 | Biogen Idec Ma Inc. | Treating stroke |
| DK2529619T3 (en) | 2005-02-17 | 2016-01-11 | Biogen Ma Inc | Treatment of neurological disorders |
| CN101171035A (zh) * | 2005-03-07 | 2008-04-30 | 健泰科生物技术公司 | 用于调控tweak和fn14活性的方法和组合物 |
| CA2607697C (en) * | 2005-05-10 | 2015-01-06 | Biogen Idec Ma Inc. | Treating and evaluating inflammatory disorders |
| EP1764109A1 (de) * | 2005-05-24 | 2007-03-21 | Xantos Biomedicine AG | Agonistische Antikörper, welche an den Tweak Rezeptor Fn14 binden und dadurch Adipositas assoziierte Phänotypen modulieren, und deren Verwendung in der Therapie |
| WO2006125632A2 (en) * | 2005-05-24 | 2006-11-30 | Rechtsanwalt Dr. Martin Prager Als Insolvenzverwalter Über Das Vermögen Der Xantos Biomedicine Ag, Pluta Rechtsanwalts Gmbh | Agonistic antibodies that bind to the tweak receptor fn14 and thereby modulate adiposity-associated phenotypes as well as their use in therapy |
| EP2460832A3 (en) * | 2005-05-27 | 2012-10-31 | Biogen Idec MA Inc. | TWEAK binding antibodies |
| WO2006130429A2 (en) * | 2005-05-27 | 2006-12-07 | Biogen Idec Ma Inc. | Treatment of cancer |
| WO2006138219A2 (en) * | 2005-06-13 | 2006-12-28 | Biogen Idec Ma Inc. | Methods of diagnosis / prognosis of inflammatory conditions |
| EP1876448A1 (en) * | 2005-09-30 | 2008-01-09 | DIGILAB BioVisioN GmbH | Method and analytical reagents for identifying therapeutics using biomarkers responsive to thiazolidinediones. |
| US20070111326A1 (en) * | 2005-11-14 | 2007-05-17 | Abbott Laboratories | Diagnostic method for proteinaceous binding pairs, cardiovascular conditions and preeclampsia |
| WO2008022349A2 (en) | 2006-08-18 | 2008-02-21 | Armagen Technologies, Inc. | Agents for blood-brain barrier delivery |
| CA2694762A1 (en) | 2007-07-27 | 2009-02-05 | Armagen Technologies, Inc. | Methods and compositions for increasing alpha-l-iduronidase activity in the cns |
| KR20100053607A (ko) * | 2007-08-03 | 2010-05-20 | 패시트 바이오테크 코포레이션 | 항-ｔｗｅａｋ 수용체 항체의 치료 용도 |
| WO2010005519A1 (en) * | 2008-06-30 | 2010-01-14 | University Of Pennsylvania | Fn14/trail fusion proteins |
| WO2010085648A2 (en) * | 2009-01-23 | 2010-07-29 | Linda Burkly C | Methods for reducing radiation-induced tissue damage |
| EP2408474B1 (en) * | 2009-03-18 | 2019-06-26 | Armagen, Inc. | Compositions and methods for blood-brain barrier delivery of igg-decoy receptor fusion proteins |
| US8093006B2 (en) | 2009-04-02 | 2012-01-10 | Hoffmann-La Roche Inc. | Antibodies against human tweak and uses thereof |
| US8663210B2 (en) | 2009-05-13 | 2014-03-04 | Novian Health, Inc. | Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy |
| HUE044865T2 (hu) | 2009-10-09 | 2019-11-28 | Armagen Inc | Eljárások és készítmények a központi idegrendszerben iduronát-2-szulfatáz-aktivitás növelésére |
| WO2011097500A2 (en) | 2010-02-04 | 2011-08-11 | University Of Louisville Research Foundation, Inc. | The tweak/fn14 system regulates skeletal muscle atrophy and regeneration |
| AU2011309689B2 (en) | 2010-09-28 | 2015-01-15 | Hadasit Medical Research Services & Development Ltd. | Compositions and methods for treatment of hematological malignancies |
| AU2012299195B9 (en) * | 2011-08-19 | 2018-05-10 | Regeneron Pharmaceuticals, Inc | Anti-Tie2 antibodies uses thereof |
| ES2983576T3 (es) | 2011-12-02 | 2024-10-23 | Armagen Inc | Métodos y composiciones para aumentar la actividad arilsulfatasa en el SNC |
| US10538589B2 (en) | 2015-01-14 | 2020-01-21 | Armagen Inc. | Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU |
| KR101843248B1 (ko) * | 2015-03-17 | 2018-03-29 | 고려대학교 세종산학협력단 | 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물 |
| JP7415939B2 (ja) * | 2018-10-31 | 2024-01-17 | アステラス製薬株式会社 | 抗ヒトＦｎ１４抗体 |
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| US554806A (en) | 1896-02-18 | Filling and bunging apparatus | ||
| US1984A (en) | 1841-02-18 | Machinery for trimming straw braid | ||
| US815330A (en) | 1903-06-15 | 1906-03-20 | Thomas J Bull | Lamp-rheostat. |
| US4109496A (en) | 1977-12-20 | 1978-08-29 | Norris Industries | Trapped key mechanism |
| ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
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| WO1994000469A1 (en) | 1992-06-26 | 1994-01-06 | Immunex Corporation | Novel tyrosine kinase |
| JP3589665B2 (ja) | 1992-10-23 | 2004-11-17 | イミュネックス・コーポレーション | 可溶性オリゴマー蛋白質の調製法 |
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| US5693506A (en) | 1993-11-16 | 1997-12-02 | The Regents Of The University Of California | Process for protein production in plants |
| US5759546A (en) * | 1994-02-04 | 1998-06-02 | Weinberg; Andrew D. | Treatment of CD4 T-cell mediated conditions |
| US5880327A (en) | 1994-09-21 | 1999-03-09 | American National Red Cross | Transgenic mammals expressing human coagulation factor VIII |
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| KR101004174B1 (ko) | 1995-06-29 | 2010-12-24 | 임뮤넥스 코포레이션 | 세포소멸을 유도하는 시토킨 |
| EA003187B1 (ru) * | 1996-08-07 | 2003-02-27 | Байоджен, Инк. | Лиганд, родственный фактору некроза опухоли |
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| ES2262518T5 (es) | 1999-06-07 | 2009-05-08 | Immunex Corporation | Antagonistas de tek. |
| US6943146B2 (en) | 2000-05-08 | 2005-09-13 | Biogen Idec Ma Inc. | Method for promoting neovascularization |
| CA2422095A1 (en) | 2000-09-14 | 2002-03-21 | Biogen, Inc. | Tweak receptor agonists as anti-angiogenic agents |
-
2000
- 2000-12-19 AU AU27315/01A patent/AU782067B2/en not_active Ceased
- 2000-12-19 US US09/742,454 patent/US6824773B2/en not_active Expired - Fee Related
- 2000-12-19 EP EP10181271A patent/EP2298333A3/en not_active Withdrawn
- 2000-12-19 WO PCT/US2000/034755 patent/WO2001045730A2/en not_active Ceased
- 2000-12-19 NZ NZ520171A patent/NZ520171A/en not_active IP Right Cessation
- 2000-12-19 ES ES00990269T patent/ES2433011T3/es not_active Expired - Lifetime
- 2000-12-19 JP JP2001546669A patent/JP5148795B2/ja not_active Expired - Fee Related
- 2000-12-19 EP EP10181389A patent/EP2298334A3/en not_active Withdrawn
- 2000-12-19 EP EP00990269.3A patent/EP1239869B1/en not_active Expired - Lifetime
- 2000-12-19 CA CA2394015A patent/CA2394015C/en not_active Expired - Fee Related
-
2002
- 2002-05-29 IL IL149922A patent/IL149922A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU782067B2 (en) | 2005-06-30 |
| AU2731501A (en) | 2001-07-03 |
| CA2394015C (en) | 2013-11-05 |
| WO2001045730A2 (en) | 2001-06-28 |
| US20020041876A1 (en) | 2002-04-11 |
| NZ520171A (en) | 2005-07-29 |
| US6824773B2 (en) | 2004-11-30 |
| JP5148795B2 (ja) | 2013-02-20 |
| EP1239869A2 (en) | 2002-09-18 |
| EP1239869B1 (en) | 2013-08-28 |
| EP2298333A2 (en) | 2011-03-23 |
| EP2298334A3 (en) | 2012-04-04 |
| WO2001045730A3 (en) | 2002-01-10 |
| IL149922A (en) | 2013-09-30 |
| EP2298334A2 (en) | 2011-03-23 |
| CA2394015A1 (en) | 2001-06-28 |
| JP2003517829A (ja) | 2003-06-03 |
| EP2298333A3 (en) | 2012-05-02 |
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