ES2421714T3 - Una preparación de liposomas catiónicos que comprende un taxano - Google Patents

Una preparación de liposomas catiónicos que comprende un taxano

Info

Publication number
ES2421714T3
ES2421714T3 ES09166622T ES09166622T ES2421714T3 ES 2421714 T3 ES2421714 T3 ES 2421714T3 ES 09166622 T ES09166622 T ES 09166622T ES 09166622 T ES09166622 T ES 09166622T ES 2421714 T3 ES2421714 T3 ES 2421714T3
Authority
ES
Spain
Prior art keywords
liposome preparation
taxane
amount
cationic liposome
mol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES09166622T
Other languages
English (en)
Inventor
Carsten Mundus
Christian Welz
Oliver Schramel
Heinrich Haas
Thomas Fichert
Brita Schulze
Toralf Peymann
Gerhard Winter
Friedrich Gruber
Michael Teifel
Uwe Michaelis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medigene AG
Original Assignee
Medigene AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP02018724A external-priority patent/EP1374864A1/en
Application filed by Medigene AG filed Critical Medigene AG
Application granted granted Critical
Publication of ES2421714T3 publication Critical patent/ES2421714T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Una preparación de liposomas catiónicos que comprende al menos un lípido catiónico en una cantidad de al menos aproximadamente 30% molar, opcionalmente al menos un compuesto anfifílico adicional en una cantidad de hasta 69,9% molar, un taxano en una cantidad de al menos 2% molar y un agente estabilizador en una cantidad de 0,1% (m/v) a 20% (m/v), caracterizada porque dicha preparación de liposomas es física y químicamente estable en solución acuosa durante al menos 12 horas a 2 hasta 8°C y al menos 4 horas a la temperatura ambiente, y caracterizada por tener un pH de entre 3 y 6, 5.
ES09166622T 2002-06-26 2003-06-26 Una preparación de liposomas catiónicos que comprende un taxano Expired - Lifetime ES2421714T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39124502P 2002-06-26 2002-06-26
US39124602P 2002-06-26 2002-06-26
EP02018724A EP1374864A1 (en) 2002-06-26 2002-08-21 Amphiphilic taxane compositions
EP03004744 2003-03-04

Publications (1)

Publication Number Publication Date
ES2421714T3 true ES2421714T3 (es) 2013-09-05

Family

ID=46168737

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09166622T Expired - Lifetime ES2421714T3 (es) 2002-06-26 2003-06-26 Una preparación de liposomas catiónicos que comprende un taxano
ES10182221.1T Expired - Lifetime ES2611054T3 (es) 2002-06-26 2003-06-26 Método para producir una preparación de liposomas catiónicos que comprende un compuesto lipófilo

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES10182221.1T Expired - Lifetime ES2611054T3 (es) 2002-06-26 2003-06-26 Método para producir una preparación de liposomas catiónicos que comprende un compuesto lipófilo

Country Status (7)

Country Link
JP (1) JP2012072188A (es)
CY (1) CY1114357T1 (es)
DK (1) DK2108362T3 (es)
ES (2) ES2421714T3 (es)
HU (1) HUE031505T2 (es)
PT (2) PT2286795T (es)
SI (2) SI2108362T1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927571A (en) * 1987-05-18 1990-05-22 Liposome Technology, Inc. Preparation of injectable doxorubicin/liposome suspension
NZ258044A (en) * 1992-11-27 1995-12-21 Faulding F H & Co Ltd Pharmaceutical composition comprising taxol, solubilising agent, an acid and an organic solvent
JPH06211645A (ja) * 1993-01-14 1994-08-02 Mitsubishi Kasei Corp リポソーム凍結乾燥製剤
GB9813100D0 (en) * 1998-06-18 1998-08-19 Secr Defence Method of forming liposomes
IT1306129B1 (it) * 1999-04-13 2001-05-30 Sigma Tau Ind Farmaceuti Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti
EP1278512A2 (en) * 2000-05-03 2003-01-29 MBT Munich Biotechnology AG Cationic diagnostic, imaging and therapeutic agents associated with activated vascular sites

Also Published As

Publication number Publication date
HUE031505T2 (en) 2017-07-28
CY1114357T1 (el) 2016-08-31
DK2108362T3 (da) 2013-09-02
JP2012072188A (ja) 2012-04-12
PT2286795T (pt) 2017-01-27
PT2108362E (pt) 2013-07-11
ES2611054T3 (es) 2017-05-04
SI2286795T1 (sl) 2017-02-28
SI2108362T1 (sl) 2013-08-30

Similar Documents

Publication Publication Date Title
DK0931788T3 (da) Metalloproteasehæmmere
BRPI0416986A (pt) preparação farmacêutica compreendendo um anticorpo contra o receptor de egf
AP1614A (en) New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents.
TR200002953T2 (tr) İki halkalı hidroksamik asit türevleri
EP1371643A3 (en) Method of preparing organic peroxyacids
HRP20020198B1 (en) Moxifloxacin formulation containing common salt
PT1003725E (pt) Fungicidas de fluoropirazoldifenilamidas
TR200201270T2 (tr) Epinastin içeren çözeltiler.
DE60036014D1 (de) Methode zur stabilisierung von benzimidazol-verbindungen
BRPI0407652A (pt) método para acentuar a eficácia de um agente ativo, composição e método para produzir a composição
ATE367165T1 (de) Xanthangummi enthaltende reepithelialisierende pharmazeutische zubereitungen
ATE430571T1 (de) Wässrige pharmazeutische formulierungen von wasserlöslichen prodrugs von propofol- verbindungen
TR200001909T2 (tr) Matris metaloprotez inhibitörleri.
HUP0400520A2 (hu) Klindamicint és cinksót tartalmazó dermatológiai készítmények
BRPI0411218A (pt) formulações alvejantes fluorescentes estáveis em estocagem
AR032933A1 (es) Compuestos que contienen creatina y creatinina
ITMI20032463A1 (it) Soluzione acquosa concentrata a base di ambroxolo
UY27373A1 (es) Formulaciones de interferón beta-humano
ES2421714T3 (es) Una preparación de liposomas catiónicos que comprende un taxano
EA200101150A1 (ru) Раствор прукалоприда для перорального применения
FR2862062B1 (fr) Lipide a et composition topique, notamment cosmetique, le comprenant
AU2001285944A1 (en) Fungicidal agent containing n-chlorotaurine and use thereof
BRPI0206922B8 (pt) composto de fragrância, composição de fragrância contendo o mesmo, e método para preparação de um composto de fragrância
BR0209820A (pt) Processo para a preparação de formulações sólidas de 3-hidróxi-3-metilbutirato de sódio
ATE359350T1 (de) Verdickte wässrige zusammensetzungen