ES2394081T3 - Cápsula de cubierta dura de dos partes fabricada de poli(1,4-alfa-D-glucano) y almidón - Google Patents
Cápsula de cubierta dura de dos partes fabricada de poli(1,4-alfa-D-glucano) y almidón Download PDFInfo
- Publication number
- ES2394081T3 ES2394081T3 ES02767147T ES02767147T ES2394081T3 ES 2394081 T3 ES2394081 T3 ES 2394081T3 ES 02767147 T ES02767147 T ES 02767147T ES 02767147 T ES02767147 T ES 02767147T ES 2394081 T3 ES2394081 T3 ES 2394081T3
- Authority
- ES
- Spain
- Prior art keywords
- starch
- poly
- glucan
- composition
- spike
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920002472 Starch Polymers 0.000 title claims abstract description 67
- 235000019698 starch Nutrition 0.000 title claims abstract description 67
- 239000008107 starch Substances 0.000 title claims abstract description 55
- 239000007887 hard shell capsule Substances 0.000 title claims abstract description 25
- WQZGKKKJIJFFOK-DVKNGEFBSA-N alpha-D-glucose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-DVKNGEFBSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 claims abstract description 57
- 239000004014 plasticizer Substances 0.000 claims abstract description 17
- 235000014633 carbohydrates Nutrition 0.000 claims abstract description 13
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 13
- 238000006116 polymerization reaction Methods 0.000 claims abstract description 11
- 229920000881 Modified starch Polymers 0.000 claims abstract description 9
- 235000019426 modified starch Nutrition 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims abstract description 7
- 239000004368 Modified starch Substances 0.000 claims abstract description 6
- 229920001503 Glucan Polymers 0.000 claims description 65
- 239000002775 capsule Substances 0.000 claims description 51
- 238000000034 method Methods 0.000 claims description 30
- 238000000465 moulding Methods 0.000 claims description 25
- 239000007864 aqueous solution Substances 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 239000000243 solution Substances 0.000 claims description 15
- 238000001816 cooling Methods 0.000 claims description 13
- 238000007654 immersion Methods 0.000 claims description 11
- 230000008569 process Effects 0.000 claims description 10
- 238000007598 dipping method Methods 0.000 claims description 9
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 239000000314 lubricant Substances 0.000 claims description 4
- 239000011257 shell material Substances 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 3
- 238000005520 cutting process Methods 0.000 claims description 3
- 235000015872 dietary supplement Nutrition 0.000 claims description 2
- 235000013373 food additive Nutrition 0.000 claims description 2
- 239000002778 food additive Substances 0.000 claims description 2
- 235000012041 food component Nutrition 0.000 claims description 2
- 230000007246 mechanism Effects 0.000 claims description 2
- 230000007723 transport mechanism Effects 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims 2
- 239000004615 ingredient Substances 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 238000001035 drying Methods 0.000 description 9
- 229920000159 gelatin Polymers 0.000 description 9
- 235000019322 gelatine Nutrition 0.000 description 9
- 108010010803 Gelatin Proteins 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 8
- 239000008273 gelatin Substances 0.000 description 8
- 235000011852 gelatine desserts Nutrition 0.000 description 8
- 239000000654 additive Substances 0.000 description 6
- 238000011049 filling Methods 0.000 description 6
- 229920001592 potato starch Polymers 0.000 description 6
- 229920000945 Amylopectin Polymers 0.000 description 5
- 229920000856 Amylose Polymers 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 230000004048 modification Effects 0.000 description 5
- 238000012986 modification Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- -1 for example Chemical class 0.000 description 4
- 238000001953 recrystallisation Methods 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 240000003183 Manihot esculenta Species 0.000 description 3
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 229920001436 collagen Polymers 0.000 description 3
- 239000002537 cosmetic Substances 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 150000002170 ethers Chemical class 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 210000002706 plastid Anatomy 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 244000062793 Sorghum vulgare Species 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 238000002441 X-ray diffraction Methods 0.000 description 2
- 125000000129 anionic group Chemical group 0.000 description 2
- 208000005881 bovine spongiform encephalopathy Diseases 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 125000002091 cationic group Chemical group 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 150000005829 chemical entities Chemical class 0.000 description 2
- 239000013065 commercial product Substances 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 230000032050 esterification Effects 0.000 description 2
- 238000005886 esterification reaction Methods 0.000 description 2
- 238000006266 etherification reaction Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000001254 oxidized starch Substances 0.000 description 2
- 235000013808 oxidized starch Nutrition 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- 150000005846 sugar alcohols Polymers 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- AFENDNXGAFYKQO-UHFFFAOYSA-N 2-hydroxybutyric acid Chemical compound CCC(O)C(O)=O AFENDNXGAFYKQO-UHFFFAOYSA-N 0.000 description 1
- DEXFNLNNUZKHNO-UHFFFAOYSA-N 6-[3-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperidin-1-yl]-3-oxopropyl]-3H-1,3-benzoxazol-2-one Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C1CCN(CC1)C(CCC1=CC2=C(NC(O2)=O)C=C1)=O DEXFNLNNUZKHNO-UHFFFAOYSA-N 0.000 description 1
- 208000031295 Animal disease Diseases 0.000 description 1
- 235000007319 Avena orientalis Nutrition 0.000 description 1
- 244000075850 Avena orientalis Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241001596957 Brama Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 235000000378 Caryota urens Nutrition 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 240000000163 Cycas revoluta Species 0.000 description 1
- 235000008601 Cycas revoluta Nutrition 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 229920002085 Dialdehyde starch Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 239000001828 Gelatine Substances 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 229920002488 Hemicellulose Polymers 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 244000151018 Maranta arundinacea Species 0.000 description 1
- 235000010103 Metroxylon rumphii Nutrition 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 240000004713 Pisum sativum Species 0.000 description 1
- 235000010582 Pisum sativum Nutrition 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 241000209056 Secale Species 0.000 description 1
- 235000007238 Secale cereale Nutrition 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 208000018756 Variant Creutzfeldt-Jakob disease Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 150000004653 carbonic acids Chemical class 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000000679 carrageenan Substances 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 229940113118 carrageenan Drugs 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 125000003636 chemical group Chemical group 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 239000005417 food ingredient Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000001840 matrix-assisted laser desorption--ionisation time-of-flight mass spectrometry Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 239000012991 xanthate Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2913—Rod, strand, filament or fiber
- Y10T428/2933—Coated or with bond, impregnation or core
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- General Preparation And Processing Of Foods (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01113347A EP1262174A1 (en) | 2001-06-01 | 2001-06-01 | Two part hard shell capsule made of poly(1,4-alpha-D-glucane) and starch |
| EP01113347 | 2001-06-01 | ||
| PCT/EP2002/005949 WO2002102355A2 (en) | 2001-06-01 | 2002-05-31 | Two part hard shell capsule made of poly (1,4-alpha-d-glucan)and starch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2394081T3 true ES2394081T3 (es) | 2013-01-17 |
Family
ID=8177607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02767147T Expired - Lifetime ES2394081T3 (es) | 2001-06-01 | 2002-05-31 | Cápsula de cubierta dura de dos partes fabricada de poli(1,4-alfa-D-glucano) y almidón |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7374780B2 (enExample) |
| EP (2) | EP1262174A1 (enExample) |
| JP (1) | JP4392686B2 (enExample) |
| ES (1) | ES2394081T3 (enExample) |
| WO (1) | WO2002102355A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1438033B1 (de) * | 2001-10-23 | 2008-06-11 | InnoGEL AG | Hartkapseln auf basis von stärke-gel und verfahren zu deren herstellung |
| JP4584146B2 (ja) * | 2003-07-09 | 2010-11-17 | 江崎グリコ株式会社 | α−１，４−グルカンおよび／またはその修飾物を含む成型物およびその製造方法 |
| JP2005194218A (ja) * | 2004-01-05 | 2005-07-21 | Ezaki Glico Co Ltd | ハードカプセルおよびその製造方法 |
| US8479656B2 (en) * | 2005-02-05 | 2013-07-09 | Hydro-Caps, Llc | Water based paintball and method for fabricating water based paintballs |
| US7905181B2 (en) * | 2005-02-05 | 2011-03-15 | Ciesiun Paul M | Bioluminescent paintball |
| US20090169633A1 (en) * | 2007-12-31 | 2009-07-02 | Ta-Ping Liao | Oral particle including pseudoephedrine hydrochloride and cetirizine dihydrochloride |
| WO2012028702A1 (de) * | 2010-09-02 | 2012-03-08 | Innogel Ag | Hartkapsel auf stärkebasis sowie tauchbeschichtungszusammensetzung, tauchbad und verfahren zur herstellung derselben |
| CA2870134C (en) * | 2012-05-02 | 2020-04-28 | Capsugel France SAS | Aqueous dispersions of hydroxypropyl methylcellulose acetate succinate (hpmcas) |
| EP3065720A1 (en) | 2013-11-04 | 2016-09-14 | Capsugel Belgium NV | Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole |
| CN114044942B (zh) * | 2021-11-24 | 2023-02-10 | 湖北人福药用辅料股份有限公司 | 一种改性淀粉胶囊壳及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4026986A (en) * | 1975-05-22 | 1977-05-31 | The Dow Chemical Company | Capsule shell |
| JPS6054322B2 (ja) * | 1977-09-30 | 1985-11-29 | 株式会社林原生物化学研究所 | 成形物の製法 |
| EG16028A (en) | 1982-03-26 | 1986-12-30 | Warner Lambert Co | Apparatus and method for molding capsules |
| US4539060A (en) | 1983-02-18 | 1985-09-03 | Warner-Lambert Company | Apparatus and method of sealing capsules |
| US4738724A (en) | 1983-11-04 | 1988-04-19 | Warner-Lambert Company | Method for forming pharmaceutical capsules from starch compositions |
| US4738818A (en) | 1986-09-29 | 1988-04-19 | Westinghouse Electric Corp. | Feedwater control in a PWR following reactor trip |
| JPH022003A (ja) | 1988-06-13 | 1990-01-08 | Canon Inc | インクジェット記録ヘッド |
| DK0559827T3 (da) | 1990-11-28 | 1997-12-15 | Scherer Corp R P | Gelatinekapsler indeholdende stivelse med højt amyloseindhold |
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| US5431917A (en) | 1992-10-08 | 1995-07-11 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
| AU7966694A (en) | 1993-07-21 | 1996-05-02 | University Of Kentucky Research Foundation, The | A multicompartment hard capsule with control release properties |
| DE19729273C2 (de) * | 1997-07-09 | 2000-08-17 | Aventis Res & Tech Gmbh & Co | Thermoplastische Mischung auf 1,4-alpha-D-Polyglucanbasis, Verfahren zu deren Herstellung und Verwendung |
| WO2000018835A1 (en) | 1998-09-30 | 2000-04-06 | Warner-Lambert Company | Modified starch film compositions |
| DE59911807D1 (de) * | 1999-11-19 | 2005-04-28 | Swiss Caps Rechte & Lizenzen | Verfahren zum Herstellen eines Stärke enthaltenden Formkörpers, homogenisierte Stärke enthaltende Masse und Vorrichtung zum Herstellen einer Weichkapsel |
-
2001
- 2001-06-01 EP EP01113347A patent/EP1262174A1/en not_active Withdrawn
-
2002
- 2002-05-31 EP EP02767147A patent/EP1411902B1/en not_active Expired - Lifetime
- 2002-05-31 US US10/478,796 patent/US7374780B2/en not_active Expired - Fee Related
- 2002-05-31 WO PCT/EP2002/005949 patent/WO2002102355A2/en not_active Ceased
- 2002-05-31 JP JP2003504943A patent/JP4392686B2/ja not_active Expired - Fee Related
- 2002-05-31 ES ES02767147T patent/ES2394081T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040234761A1 (en) | 2004-11-25 |
| EP1411902A2 (en) | 2004-04-28 |
| WO2002102355A3 (en) | 2004-02-26 |
| EP1262174A1 (en) | 2002-12-04 |
| JP2005532980A (ja) | 2005-11-04 |
| US7374780B2 (en) | 2008-05-20 |
| JP4392686B2 (ja) | 2010-01-06 |
| EP1411902B1 (en) | 2012-10-17 |
| WO2002102355A2 (en) | 2002-12-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU761439B2 (en) | Fast-dispersing dosage forms containing fish gelatin | |
| CA2360647C (en) | Fast dispersing dosage forms free of gelatin | |
| US6509040B1 (en) | Fast dispersing dosage forms essentially free of mammalian gelatin | |
| ES2394081T3 (es) | Cápsula de cubierta dura de dos partes fabricada de poli(1,4-alfa-D-glucano) y almidón | |
| Nagar et al. | Insights into Polymers: Film Formers in Mouth Dissolving Films. | |
| US8013148B2 (en) | Molded object comprising α-1,4-glucans and/or modifications thereof and process for producing the same | |
| US7662406B1 (en) | Chewable softgel capsules | |
| JP2003504326A (ja) | 改質澱粉とイオタ−カラギーナンとを含有するフィルム形成性組成物およびこれを用いる軟質カプセルの製造方法 | |
| EP2600849A1 (en) | Film-forming composition for soft capsules | |
| JP2005509052A (ja) | 多糖類を基剤とする網状構造およびその製造方法 | |
| KR101560572B1 (ko) | 천연타피오카전분 및 풀루란을 포함하는 가식성 필름 및 이의 제조방법 | |
| US20070034827A1 (en) | Blends of gelling and non-gelling starches with gellan gums and plasticizer | |
| US10828261B2 (en) | Fast dissolving tablet formulations and methods of making thereof | |
| JP4574738B1 (ja) | 生分解性成形品 | |
| JP4242266B2 (ja) | カプセル剤皮組成物 | |
| US20070128267A1 (en) | Blends of gelling and non-gelling starches with gellan gums and plasticizer | |
| US8383134B2 (en) | Biodegradable material based on opened starch | |
| CN121129791A (zh) | 一种用于抗肿瘤的软胶囊及其制备方法 | |
| PT103646A (pt) | Composição biodegradável à base de amido, respectiva utilização e processo para a sua obtenção | |
| HK1186973A (en) | Film-forming composition for soft capsules |