ES2376225T3 - Genes de elongasa y usos de los mismos. - Google Patents

Genes de elongasa y usos de los mismos. Download PDF

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Publication number
ES2376225T3
ES2376225T3 ES03756242T ES03756242T ES2376225T3 ES 2376225 T3 ES2376225 T3 ES 2376225T3 ES 03756242 T ES03756242 T ES 03756242T ES 03756242 T ES03756242 T ES 03756242T ES 2376225 T3 ES2376225 T3 ES 2376225T3
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Prior art keywords
acid
fatty acids
genes
docosapentaenoic
dgla
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Expired - Lifetime
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ES03756242T
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ES2376225T5 (es
Inventor
Pradip Mukerji
Amanda E. Leonard
Yung-Sheng Huang
Suzette L. Pereira
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Abbott Laboratories
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Abbott Laboratories
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
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    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/606Nucleosides; Nucleotides; Nucleic acids
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
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    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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    • C12N9/10Transferases (2.)
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    • A01K2217/00Genetically modified animals
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Abstract

Una secuencia de nucleótidos aislada o fragmento de la misma que comprende o es complementaria de una secuencia de nucleótidos que codifica un polipéptido que tiene actividad elongasa, en la que el polipéptido elonga ácidos grasos poliinsaturados de cadena de 20 carbonos de longitud y en la que la secuencia de aminoácidos de dicho polipéptido tiene al menos 50 % de identidad con una secuencia de aminoácidos que comprende SEC ID Nº: 121.
ES03756242.8T 2002-05-29 2003-05-29 Genes de elongasa y usos de los mismos Expired - Lifetime ES2376225T5 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US156911 2002-05-29
US10/156,911 US20030163845A1 (en) 1998-09-02 2002-05-29 Elongase genes and uses thereof
PCT/US2003/016863 WO2003102138A2 (en) 2002-05-29 2003-05-29 Elongase genes and uses thereof

Publications (2)

Publication Number Publication Date
ES2376225T3 true ES2376225T3 (es) 2012-03-12
ES2376225T5 ES2376225T5 (es) 2015-01-12

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ID=29709610

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Application Number Title Priority Date Filing Date
ES03756242.8T Expired - Lifetime ES2376225T5 (es) 2002-05-29 2003-05-29 Genes de elongasa y usos de los mismos

Country Status (10)

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US (3) US20030163845A1 (es)
EP (1) EP1507855B2 (es)
JP (1) JP4434944B2 (es)
AT (1) ATE538198T1 (es)
AU (1) AU2003243335B2 (es)
BR (1) BR0306655A (es)
CA (1) CA2487095C (es)
ES (1) ES2376225T5 (es)
MX (1) MXPA04011902A (es)
WO (1) WO2003102138A2 (es)

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US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
EP2169053B1 (de) 2003-08-01 2015-09-09 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
US9458436B2 (en) 2004-02-27 2016-10-04 Basf Plant Science Gmbh Method for producing polyunsaturated fatty acids in transgenic plants
EP1720988B1 (de) 2004-02-27 2011-10-12 BASF Plant Science GmbH Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
CN102559364B (zh) 2004-04-22 2016-08-17 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
BRPI0510132A (pt) 2004-04-22 2007-10-02 Commw Scient Ind Res Org sìntese de ácidos graxos poliinsaturados de cadeia longa por células recombinantes
ES2351973T3 (es) 2004-06-04 2011-02-14 Fluxome Sciences A/S Células metabólicamente modificadas por ingeniería para la producción de ácidos grasos poliinsaturados.
US8092839B2 (en) * 2004-12-13 2012-01-10 Swing Aerobics Licensing, Inc. Medicament for treatment of cancer and other diseases
US8431165B2 (en) * 2004-12-13 2013-04-30 Swing Aerobics Licensing, Inc. Medicament for treatment of cancer and other diseases
JP5181486B2 (ja) * 2006-02-16 2013-04-10 大正製薬株式会社 亜鉛化合物配合経口用組成物
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
EP2059588A4 (en) 2006-08-29 2010-07-28 Commw Scient Ind Res Org FATTY ACID SYNTHESIS
CA2687964A1 (en) 2007-06-01 2009-02-19 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
US7892792B2 (en) 2008-06-27 2011-02-22 Indian Institute Of Science Cells expressing Pichia cytochrome C
CN114045301A (zh) 2008-11-18 2022-02-15 联邦科学技术研究组织 产生ω-3脂肪酸的酶和方法
DK2740797T3 (da) * 2011-08-04 2017-02-20 Suntory Holdings Ltd Protein med aktivitet til at fremme fedtsyreforlængelse, derfor kodende gen samt anvendelse deraf
US8816111B2 (en) 2012-06-15 2014-08-26 Commonwealth Scientific And Industrial Research Organisation Lipid comprising polyunsaturated fatty acids
RU2019101182A (ru) * 2013-03-27 2019-03-04 Сантори Холдингз Лимитед Промотор, проявляющий высокую экспрессионную активность в микроорганизмах mortierella
CN104726473B (zh) 2013-12-18 2020-02-14 联邦科学技术研究组织 包含二十二碳六烯酸的提取的植物脂质
CN105219789B (zh) 2014-06-27 2023-04-07 联邦科学技术研究组织 包含二十二碳五烯酸的提取的植物脂质
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