ES2372707T3 - Inhibidores de la ikk-beta serina-treonina proteína quinasa. - Google Patents
Inhibidores de la ikk-beta serina-treonina proteína quinasa. Download PDFInfo
- Publication number
- ES2372707T3 ES2372707T3 ES07824358T ES07824358T ES2372707T3 ES 2372707 T3 ES2372707 T3 ES 2372707T3 ES 07824358 T ES07824358 T ES 07824358T ES 07824358 T ES07824358 T ES 07824358T ES 2372707 T3 ES2372707 T3 ES 2372707T3
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- Prior art keywords
- cyclopentyl
- carbamoylamino
- carbamoyl
- alkyl
- phenyl
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Classifications
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- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
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- Pain & Pain Management (AREA)
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- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0621720 | 2006-11-01 | ||
| GB0621720A GB0621720D0 (en) | 2006-11-01 | 2006-11-01 | Inhibitors of ikk- serine-threonine protein kinase |
| GB0715470A GB0715470D0 (en) | 2007-08-09 | 2007-08-09 | IKK- serine-threonine protein kinase inhibitors |
| GB0715470 | 2007-08-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2372707T3 true ES2372707T3 (es) | 2012-01-25 |
Family
ID=39015937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07824358T Active ES2372707T3 (es) | 2006-11-01 | 2007-10-29 | Inhibidores de la ikk-beta serina-treonina proteína quinasa. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8003695B2 (enExample) |
| EP (1) | EP2078007B1 (enExample) |
| JP (1) | JP2010508336A (enExample) |
| KR (1) | KR20090077975A (enExample) |
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| AU (1) | AU2007315943A1 (enExample) |
| BR (1) | BRPI0718056A2 (enExample) |
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| MX (1) | MX2009004442A (enExample) |
| NZ (1) | NZ576705A (enExample) |
| WO (1) | WO2008053182A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0619753D0 (en) * | 2006-10-06 | 2006-11-15 | Chroma Therapeutics Ltd | Enzyme inhibitors |
| GB0803747D0 (en) | 2008-02-29 | 2008-04-09 | Martin | Enzyme and receptor modulation |
| US20110039920A1 (en) * | 2008-04-23 | 2011-02-17 | Chroma Therapeutics Ltd. | Inhibitors of ikk-beta serine-theronine protein kinase |
| MX2010011643A (es) * | 2008-04-26 | 2010-11-30 | Chroma Therapeutics Ltd | Tiofencarboxamidas sustituidas como inhibidores de la proteina cinasa ikk-beta serina, treonina. |
| US8470889B2 (en) * | 2008-11-26 | 2013-06-25 | Trt Pharma Inc. | Hybrid-ionone and curcumin molecules as anticancer agents |
| GB0903480D0 (en) | 2009-02-27 | 2009-04-08 | Chroma Therapeutics Ltd | Enzyme Inhibitors |
| GB0907120D0 (en) * | 2009-04-24 | 2009-06-03 | Chroma Therapeutics Ltd | Inhibitors of IKK-ß serine-threonine protein kinase |
| GB201211310D0 (en) | 2012-06-26 | 2012-08-08 | Chroma Therapeutics Ltd | CSF-1R kinase inhibitors |
| SI3222616T1 (sl) | 2012-10-17 | 2019-10-30 | Macrophage Pharma Ltd | N-(2-(4-(6-amino-5-(2,4-difluorobenzoil)-2-oksopiridin-1(2H)-IL)-3,5- difluorofenil)etil)-L-alanin in njegov terbutil ester |
| HRP20181109T1 (hr) * | 2013-12-11 | 2018-11-02 | Biogen Ma Inc. | Spojevi biarila korisni za liječenje ljudskih bolesti u onkologiji, neurologiji i imunologiji |
| GB201713975D0 (en) | 2017-08-31 | 2017-10-18 | Macrophage Pharma Ltd | Medical use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
| SE0300092D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
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2007
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- 2007-10-29 EP EP07824358A patent/EP2078007B1/en not_active Not-in-force
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- 2007-10-29 EA EA200900616A patent/EA200900616A1/ru unknown
- 2007-10-29 AU AU2007315943A patent/AU2007315943A1/en not_active Abandoned
- 2007-10-29 JP JP2009535115A patent/JP2010508336A/ja not_active Withdrawn
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- 2007-10-29 AT AT07824358T patent/ATE522516T1/de not_active IP Right Cessation
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- 2007-10-29 MX MX2009004442A patent/MX2009004442A/es active IP Right Grant
- 2007-10-29 CA CA002668338A patent/CA2668338A1/en not_active Abandoned
- 2007-10-29 DK DK07824358.1T patent/DK2078007T3/da active
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2009
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20090077975A (ko) | 2009-07-16 |
| JP2010508336A (ja) | 2010-03-18 |
| IL198267A0 (en) | 2009-12-24 |
| ATE522516T1 (de) | 2011-09-15 |
| EP2078007B1 (en) | 2011-08-31 |
| US20100087515A1 (en) | 2010-04-08 |
| DK2078007T3 (da) | 2011-12-12 |
| BRPI0718056A2 (pt) | 2013-11-05 |
| EP2078007A1 (en) | 2009-07-15 |
| WO2008053182A1 (en) | 2008-05-08 |
| NZ576705A (en) | 2011-12-22 |
| EA200900616A1 (ru) | 2010-04-30 |
| US8003695B2 (en) | 2011-08-23 |
| CA2668338A1 (en) | 2008-05-08 |
| AU2007315943A1 (en) | 2008-05-08 |
| MX2009004442A (es) | 2009-05-22 |
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