ES2371287T3 - Expresión diferencial de la citocina en cáncer humano. - Google Patents

Expresión diferencial de la citocina en cáncer humano. Download PDF

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Publication number
ES2371287T3
ES2371287T3 ES07764767T ES07764767T ES2371287T3 ES 2371287 T3 ES2371287 T3 ES 2371287T3 ES 07764767 T ES07764767 T ES 07764767T ES 07764767 T ES07764767 T ES 07764767T ES 2371287 T3 ES2371287 T3 ES 2371287T3
Authority
ES
Spain
Prior art keywords
tumor
cytokine
agent
cells
neutralizing agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07764767T
Other languages
English (en)
Spanish (es)
Inventor
Giorgio Stassi
Christian Gieffers
Oliver Hill
Meinolf Thiemann
Matilde Todaro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apogenix AG
Original Assignee
Apogenix AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apogenix AG filed Critical Apogenix AG
Application granted granted Critical
Publication of ES2371287T3 publication Critical patent/ES2371287T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
ES07764767T 2006-06-21 2007-06-21 Expresión diferencial de la citocina en cáncer humano. Active ES2371287T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06012754 2006-06-21
EP06012754 2006-06-21

Publications (1)

Publication Number Publication Date
ES2371287T3 true ES2371287T3 (es) 2011-12-29

Family

ID=38359749

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07764767T Active ES2371287T3 (es) 2006-06-21 2007-06-21 Expresión diferencial de la citocina en cáncer humano.

Country Status (12)

Country Link
US (1) US20090324616A1 (fr)
EP (1) EP2041576B1 (fr)
JP (1) JP2010514409A (fr)
CN (1) CN101529253A (fr)
AT (1) ATE520032T1 (fr)
AU (1) AU2007263265A1 (fr)
BR (1) BRPI0713484A2 (fr)
CA (1) CA2656379A1 (fr)
DK (1) DK2041576T3 (fr)
ES (1) ES2371287T3 (fr)
RU (1) RU2009101783A (fr)
WO (1) WO2007147600A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007107349A1 (fr) * 2006-03-22 2007-09-27 Apogenix Gmbh Anticorps spécifique de l'il-4 humaine pour le traitement du cancer
EP2049147A2 (fr) * 2006-07-06 2009-04-22 Apogenix GmbH Mutéines d'il-4 humaines combinees avec des chemo-therapeutiques ou des pro-apoptotiques dans le traitement du cancer
DK2875045T3 (en) * 2012-07-18 2018-07-02 Apogenix Ag COMPOSITION comprising a mixture of CD95-FC ISOFORMs
WO2015138638A1 (fr) 2014-03-11 2015-09-17 Theraly Pharmaceuticals, Inc. Agonistes de récepteur de protéine trail à action prolongée pour le traitement de maladies auto-immunes
EP3209382B1 (fr) * 2014-10-24 2020-11-25 Calidi Biotherapeutics, Inc. Technique d'immunotherapie combinee pour le traitement du cancer
US10105436B2 (en) 2015-08-11 2018-10-23 Calidi Biotherapeutics, Inc. Smallpox vaccine for cancer treatment
EA038551B1 (ru) 2015-12-17 2021-09-14 Дзе Джонс Хопкинс Юниверсити Способ лечения или профилактики системного склероза
WO2017177148A1 (fr) 2016-04-07 2017-10-12 The Johns Hopkins University Compositions et procédés de traitement de la pancréatite et de la douleur avec des agonistes du récepteur de mort
JP2020513574A (ja) * 2016-11-24 2020-05-14 ヒュベット バイオ, インコーポレイテッドHuvet Bio, Inc. 疾患の診断用組成物
AU2018327225A1 (en) * 2017-09-06 2020-02-27 Fred Hutchinson Cancer Center Strep-tag specific chimeric receptors and uses thereof
US11505782B2 (en) 2018-06-04 2022-11-22 Calidi Biotherapeutics, Inc. Cell-based vehicles for potentiation of viral therapy

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU643427B2 (en) 1988-10-31 1993-11-18 Immunex Corporation Interleukin-4 receptors
DE4137333A1 (de) * 1991-11-13 1993-05-19 W Prof Dr Sebald Therapeutische mittel, die antagonisten oder partielle agonisten des humanen interleukin 4 sind oder diese enthalten, hil-4-mutantenproteine sowie vefahren zu deren herstellung
US6534051B1 (en) * 1992-11-20 2003-03-18 University Of Medicine And Dentistry Of New Jersey Cell type specific gene transfer using retroviral vectors containing antibody-envelope fusion proteins and wild-type envelope fusion proteins
KR100362340B1 (ko) 1993-09-07 2003-02-26 스미스클라인비이참피이엘시이 인터로이킨-4(il4)매개된질환의치료에유용한재조합il4항체
DE4423131A1 (de) * 1994-07-01 1996-01-04 Bayer Ag Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
SK283096B6 (sk) * 1994-07-05 2003-02-04 Steeno Research Group A/S Imunomodulátory
CN1117155C (zh) 1994-07-29 2003-08-06 史密丝克莱恩比彻姆有限公司 新型化合物
US6664227B1 (en) * 1996-03-01 2003-12-16 Genetics Institute, Llc Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains
US5710023A (en) * 1996-03-01 1998-01-20 Genetics Institute, Inc. IL-13 cytokine receptor chain
US20030124125A1 (en) * 1996-04-05 2003-07-03 South Alabama Medical Science Foundation Oncofetal antigen specific T-lymphocyte mediated immune response: manipulation and uses of oncofetal antigen specific CD4, CD8 cytotoxic and suppressor T cells and interleukin-10
US6028176A (en) * 1996-07-19 2000-02-22 Bayer Corporation High-affinity interleukin-4 muteins
US6905684B1 (en) * 1997-11-10 2005-06-14 Mochida Pharmaceutical Co., Ltd. Preventives and remedies for diffuse lung diseases
JPH11312463A (ja) * 1998-04-28 1999-11-09 Hitachi Ltd 配線基板およびそれを用いたガス放電型表示装置
CA2404365A1 (fr) * 2000-03-31 2001-10-11 Idec Pharmaceutical Corporation Utilisation combinee d'anticorps ou d'antagonistes anti-cytokine et d'anti-cd20 pour le traitement du lymphome b
AU2001273413A1 (en) * 2000-07-12 2002-01-21 Immunex Corporation Method for treating cancer using an interleukin- 4 antagonist
US20040023337A1 (en) * 2001-10-26 2004-02-05 Heavner George A. IL-13 mutein proteins, antibodies, compositions, methods and uses
US20040023338A1 (en) * 2001-10-26 2004-02-05 Heavner George A. IL-4 mutein proteins, antibodies, compositions, methods and uses
EP1444989A1 (fr) 2003-02-07 2004-08-11 Giorgio Dr. Stassi Sensibilisation de cellules à l'apoptose par bloquage selective de cytokines
US7501121B2 (en) * 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
AR049390A1 (es) * 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
EP1824886B1 (fr) * 2004-11-17 2010-12-22 Amgen Inc. Anticorps monoclonaux entierement humains diriges contre l'il-13
US20070122855A1 (en) * 2005-11-28 2007-05-31 Targetgen Inc. Methods for diagnosing hepatocellular carcinoma
WO2007107349A1 (fr) * 2006-03-22 2007-09-27 Apogenix Gmbh Anticorps spécifique de l'il-4 humaine pour le traitement du cancer
EP2049147A2 (fr) * 2006-07-06 2009-04-22 Apogenix GmbH Mutéines d'il-4 humaines combinees avec des chemo-therapeutiques ou des pro-apoptotiques dans le traitement du cancer

Also Published As

Publication number Publication date
CN101529253A (zh) 2009-09-09
EP2041576A2 (fr) 2009-04-01
WO2007147600A2 (fr) 2007-12-27
AU2007263265A1 (en) 2007-12-27
ATE520032T1 (de) 2011-08-15
RU2009101783A (ru) 2010-07-27
DK2041576T3 (da) 2011-12-05
WO2007147600A3 (fr) 2008-04-10
US20090324616A1 (en) 2009-12-31
EP2041576B1 (fr) 2011-08-10
JP2010514409A (ja) 2010-05-06
CA2656379A1 (fr) 2007-12-27
BRPI0713484A2 (pt) 2012-11-06

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