ES2358397T1 - CARRAGENAN MODIFIED THROUGH ION EXCHANGE. - Google Patents

CARRAGENAN MODIFIED THROUGH ION EXCHANGE. Download PDF

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Publication number
ES2358397T1
ES2358397T1 ES09718931T ES09718931T ES2358397T1 ES 2358397 T1 ES2358397 T1 ES 2358397T1 ES 09718931 T ES09718931 T ES 09718931T ES 09718931 T ES09718931 T ES 09718931T ES 2358397 T1 ES2358397 T1 ES 2358397T1
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carrageenan
extract
ion exchange
content
temperature
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ES2358397T3 (en
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Jens Eskil Trudsoe
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CP Kelco US Inc
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CP Kelco US Inc
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/731Carrageenans
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/256Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)

Abstract

Una composición caracterizada porque comprende un iota carragenano que ha sido sometido a un proceso de intercambio iónico, en donde el iota carragenano comprende: un contenido de potasio de aproximadamente 6 mg/g hasta aproximadamente 35 mg/g de carragenano; un contenido de calcio de menos de aproximadamente 13 mg/g de carragenano; y un contenido de magnesio inferior a aproximadamente 5 mg/g de carragenano.A composition characterized in that it comprises a carrageenan iota that has undergone an ion exchange process, wherein the carrageenan iota comprises: a potassium content of about 6 mg / g to about 35 mg / g of carrageenan; a calcium content of less than about 13 mg / g carrageenan; and a magnesium content of less than about 5 mg / g carrageenan.

Claims (22)

1. Una composición caracterizada porque comprende un iota carragenano que ha sido sometido a un proceso de intercambio iónico, en donde el iota carragenano comprende:1. A composition characterized in that it comprises a carrageenan iota that has been subjected to an ion exchange process, wherein the carrageenan iota comprises: un contenido de potasio de aproximadamente 6 mg/g hasta aproximadamente 35 mg/g de carragenano;a potassium content of about 6 mg / g to about 35 mg / g carrageenan; un contenido de calcio de menos de aproximadamente 13 mg/g de carragenano; ya calcium content of less than approximately 13 mg / g carrageenan; Y un contenido de magnesio inferior a aproximadamente 5 mg/g de carragenano.a magnesium content less than approximately 5 mg / g carrageenan. 2. La composición de acuerdo con la reivindicación 1, caracterizada porque el iota carragenano es carragenano extraído tradicionalmente y tiene una temperatura de gelación de entre aproximadamente 18ºC hasta aproximadamente 30ºC, y una temperatura de fusión de entre aproximadamente 27ºC hasta aproximadamente 37ºC.2. The composition according to claim 1, characterized in that the carrageenan iota is traditionally extracted carrageenan and has a gelation temperature between about 18 ° C to about 30 ° C, and a melting temperature between about 27 ° C to about 37 ° C. 3. La composición de acuerdo con la reivindicación 1, en donde el iota carragenano es carragenano extraído en forma neutra y tiene una temperatura de gelación de entre aproximadamente 5ºC hasta aproximadamente 17ºC, y una temperatura de fusión de entre aproximadamente 17ºC hasta aproximadamente 27ºC.3. The composition according to the claim 1, wherein the iota carragenano is carragenano Neutrally extracted and has a gelation temperature of between about 5 ° C to about 17 ° C, and a melting temperature between about 17 ° C to approximately 27 ° C. 4. Una composición caracterizada porque comprende un kappa carragenano extraído tradicionalmente que ha sido sometido a un proceso de intercambio iónico, en donde el kappa carragenano comprende:4. A composition characterized in that it comprises a traditionally extracted carrageenan kappa that has been subjected to an ion exchange process, wherein the carrageenan kappa comprises: un contenido de potasio de aproximadamente 5 mg/g hasta aproximadamente 30 mg/g de carragenano;a potassium content of approximately 5 mg / g to about 30 mg / g carrageenan; un contenido de calcio de menos de aproximadamente 7 mg/g de carragenano; ya calcium content of less than approximately 7 mg / g carrageenan; Y un contenido de magnesio inferior a aproximadamente 0,2 mg/g de carragenano.a magnesium content less than approximately 0.2 mg / g carrageenan. 5. Una composición caracterizada porque comprende un kappa carragenano extraído en forma neutra que ha sido sometido a un proceso de intercambio iónico, en donde el kappa carragenano compren-
de:
5. A composition characterized in that it comprises a neutrally extracted carrageenan kappa that has undergone an ion exchange process, wherein the carrageenan kappa comprises
from:
un contenido de potasio de aproximadamente 4 mg/g hasta aproximadamente 30 mg/g de carragenano;a potassium content of approximately 4 mg / g to about 30 mg / g carrageenan; un contenido de calcio inferior a aproximadamente 3 mg/g de carragenano; ya calcium content lower than approximately 3 mg / g carrageenan; Y un contenido de magnesio inferior a aproximadamente 3 mg/g de carragenano.a magnesium content less than approximately 3 mg / g carrageenan.
6. La composición de acuerdo con la reivindicación 4, caracterizada porque el carragenano tiene una temperatura de gelación de entre aproximadamente 10ºC hasta aproximadamente 27ºC, y una temperatura de fusión de entre aproximadamente 23ºC hasta aproximadamente 43ºC.6. The composition according to claim 4, characterized in that the carrageenan has a gelation temperature of between about 10 ° C to about 27 ° C, and a melting temperature of between about 23 ° C to about 43 ° C. 7. La composición de acuerdo con la reivindicación 5, caracterizada porque el carragenano tiene una temperatura de gelación de entre aproximadamente 10ºC hasta aproximadamente 35ºC, y una temperatura de fusión de entre aproximadamente 23ºC hasta aproximadamente 45ºC.7. The composition according to claim 5, characterized in that the carrageenan has a gelation temperature of between about 10 ° C to about 35 ° C, and a melting temperature of between about 23 ° C to about 45 ° C. 8. El uso del carragenano de acuerdo con la reivindicación 1, 4 ó 5, caracterizado porque sirve para preparar un producto de cuidado personal, un producto alimenticio, un producto para el hogar, o un producto farmacéutico.8. The use of carrageenan according to claim 1, 4 or 5, characterized in that it serves to prepare a personal care product, a food product, a household product, or a pharmaceutical product. 9. Un proceso para producir una composición de carragenano sometido a intercambio iónico, caracterizado porque comprende las etapas de:9. A process for producing a carrageenan composition subjected to ion exchange, characterized in that it comprises the steps of: extraer un material de inicio de carragenano con una solución de tratamiento acuoso para formar un extracto de iota o kappa carragenano;extract a starting material of carrageenan with an aqueous treatment solution to form an iota extract or kappa carragenano; poner en contacto el extracto de carragenano con un material de intercambio iónico catiónico ácido y reducir el contenido catiónico del extracto de carragenano para producir un extracto de carragenano obtenido por intercambio iónico.contact the carrageenan extract with an acid cationic ion exchange material and reduce the cationic content of carrageenan extract to produce a carrageenan extract obtained by ion exchange. 10. El proceso de acuerdo con la reivindicación 9, caracterizado porque la etapa de contacto incluye disolver el extracto de carragenano en agua para formar una solución de extracto y agregar el material de intercambio iónico a la solución de extracto en un primer nivel de concentración, en donde el primer nivel de concentración es igual o inferior a aproximadamente 200 g de material de intercambio iónico por litro de solución de extracto.10. The process according to claim 9, characterized in that the contact step includes dissolving the carrageenan extract in water to form an extract solution and adding the ion exchange material to the extract solution at a first concentration level, wherein the first level of concentration is equal to or less than about 200 g of ion exchange material per liter of extract solution. 11. El proceso de acuerdo con la reivindicación 10, caracterizado porque comprende la etapa de mezclar el extracto de carragenano obtenido por intercambio iónico con un segundo extracto de carragenano obtenido por intercambio iónico que: (1) es un extracto de iota o kappa carragenano; y (2) ha sido tratado con un material de intercambio iónico catiónico ácido en un segundo nivel de concentración que es diferente del primer nivel de concentración.11. The process according to claim 10, characterized in that it comprises the step of mixing the carrageenan extract obtained by ion exchange with a second carrageenan extract obtained by ion exchange which: (1) is an extract of iota or kappa carrageenan; and (2) has been treated with an acid cationic ion exchange material at a second concentration level that is different from the first concentration level. 12. El proceso de acuerdo con la reivindicación 10, caracterizado porque el primer nivel de concentración es desde aproximadamente 1,25 g/g de carragenano hasta aproximadamente 10 g/g de carragenano.12. The process according to claim 10, characterized in that the first concentration level is from about 1.25 g / g of carrageenan to about 10 g / g of carrageenan. 13. El proceso de acuerdo con la reivindicación 9, caracterizado porque la etapa de contacto dura desde aproximadamente 5 hasta aproximadamente 30 minutos.13. The process according to claim 9, characterized in that the contact stage lasts from about 5 to about 30 minutes. 14. El extracto de obtenido por intercambio preparado de acuerdo con la reivindicación 9, caracterizado porque el extracto de carragenano es un iota extracto de carragenano y el extracto obtenido por intercambio iónico tiene un contenido de potasio desde aproximadamente 6 mg/g hasta aproximadamente 35 mg/g de carragenano; un contenido de calcio inferior a aproximadamente 13 mg/g de carragenano; y un contenido de magnesio inferior a aproximadamente 5 mg/g de carragenano.14. The extract obtained by exchange prepared according to claim 9, characterized in that the carrageenan extract is an iota carrageenan extract and the extract obtained by ion exchange has a potassium content from about 6 mg / g to about 35 mg / g carrageenan; a calcium content of less than about 13 mg / g carrageenan; and a magnesium content of less than about 5 mg / g carrageenan. 15. El extracto obtenido por intercambio iónico preparado de acuerdo con la reivindicación 9, caracterizado porque el extracto de carragenano es un extracto de kappa carragenano neutro y el extracto obtenido por intercambio tiene un contenido de potasio desde aproximadamente 4 mg/g hasta aproximadamente 30 mg/g de carragenano; un contenido de calcio inferior a aproximadamente 3 mg/g de carragenano; y un contenido de magnesio inferior a aproximadamente 3 mg/g de carragenano.15. The extract obtained by ion exchange prepared according to claim 9, characterized in that the carrageenan extract is a neutral carrageenan kappa extract and the extract obtained by exchange has a potassium content from about 4 mg / g to about 30 mg / g carrageenan; a calcium content of less than about 3 mg / g carrageenan; and a magnesium content of less than about 3 mg / g carrageenan. 16. El extracto obtenido por intercambio iónico preparado de acuerdo con la reivindicación 9, caracterizado porque el extracto de carragenano es un extracto de kappa carragenano tradicional y el extracto obtenido por intercambio iónico tiene un contenido de potasio desde aproximadamente 5 mg/g hasta aproximadamente 30 mg/g de carragenano; un contenido de calcio inferior a aproximadamente 7 mg/g de carragenano; y un contenido de magnesio inferior a aproximadamente 0,2 mg/g de carragenano.16. The extract obtained by ion exchange prepared according to claim 9, characterized in that the carrageenan extract is a traditional carrageenan kappa extract and the extract obtained by ion exchange has a potassium content from about 5 mg / g to about 30 mg / g carrageenan; a calcium content of less than about 7 mg / g carrageenan; and a magnesium content of less than about 0.2 mg / g carrageenan. 17. Un proceso para preparar un producto de carragenano caracterizado porque comprende las etapas de:17. A process for preparing a carrageenan product characterized in that it comprises the steps of: (a) proveer un primer extracto de carragenano que tiene una primera temperatura de gelación y una primera temperatura de fusión;(a) provide a first carrageenan extract which has a first gelation temperature and a first melting temperature; (b) proveer un segundo extracto de carragenano obtenido por intercambio iónico que tiene una segunda temperatura de gelación que es diferente de la primera temperatura de gelación y una segunda temperatura de fusión que es diferente de la primera temperatura de fusión;(b) provide a second carrageenan extract obtained by ion exchange having a second temperature of gelation that is different from the first gelation temperature and a second melting temperature that is different from the first melting temperature; (c) mezclar el primer extracto de carragenano y el segundo carragenano obtenido por intercambio iónico para formar un producto de carragenano que tiene una tercera temperatura de gelación que está entre la primera y la segunda temperatura de gelación y una tercera temperatura de fusión que está entre la primera y la segunda temperatura de fusión.(c) mix the first carrageenan extract and the second carrageenan obtained by ion exchange to form a carrageenan product that has a third temperature of gelation that is between the first and the second temperature of gelation and a third melting temperature that is between the first and second melting temperature. 18. El proceso de acuerdo con la reivindicación 17, caracterizado porque la etapa de proveer un segundo extracto de carragenano obtenido por intercambio iónico comprende18. The process according to claim 17, characterized in that the step of providing a second carrageenan extract obtained by ion exchange comprises (a) proveer un segundo extracto de carragenano; y(a) provide a second carrageenan extract; Y (b) poner en contacto el segundo extracto de carragenano con un material de intercambio iónico catiónico ácido y reducir el contenido catiónico del segundo extracto de carragenano par producir el segundo extracto de carragenano obtenido por intercambio
iónico.
(b) contacting the second carrageenan extract with an acid cationic ion exchange material and reducing the cationic content of the second carrageenan extract to produce the second carrageenan extract obtained by exchange
ionic.
19. El proceso de acuerdo con la reivindicación 17, caracterizado porque el primer extracto de carragenano es un iota carragenano extraído tradicionalmente y la tercera temperatura de gelación es desde aproximadamente 18ºC hasta aproximadamente 40ºC y la tercera temperatura de fusión es desde aproximadamente 27ºC hasta aproximadamente 47ºC.19. The process according to claim 17, characterized in that the first carrageenan extract is a traditionally extracted carrageenan iota and the third gelation temperature is from about 18 ° C to about 40 ° C and the third melting temperature is from about 27 ° C to about 47 ° C . 20. El proceso de acuerdo con la reivindicación 17, caracterizado porque el primer extracto de carragenano es un iota carragenano extraído en forma neutra y la tercera temperatura de gelación es desde aproximadamente 5ºC hasta aproximadamente 25ºC y la tercera temperatura de fusión es desde aproximadamente 17ºC hasta aproximadamente 38ºC.20. The process according to claim 17, characterized in that the first carrageenan extract is a neutrally extracted carrageenan iota and the third gelation temperature is from about 5 ° C to about 25 ° C and the third melting temperature is from about 17 ° C to approximately 38 ° C. 21. El proceso de acuerdo con la reivindicación 17, caracterizado porque el primer extracto de carragenano es un kappa carragenano extraído tradicionalmente y la tercera temperatura de gelación es desde aproximadamente 10ºC hasta aproximadamente 37ºC y la tercera temperatura de fusión es desde aproximadamente 23ºC hasta aproximadamente 63ºC.21. The process according to claim 17, characterized in that the first carrageenan extract is a traditionally extracted carrageenan kappa and the third gelation temperature is from about 10 ° C to about 37 ° C and the third melting temperature is from about 23 ° C to about 63 ° C . 22. El proceso de acuerdo con la reivindicación 17, caracterizado porque el primer extracto de carragenano es un kappa carragenano extraído en forma neutra y la tercera temperatura de gelación es desde aproximadamente 10ºC hasta aproximadamente 38ºC y la tercera temperatura de fusión es desde aproximadamente 23ºC hasta aproximadamente
53ºC.
22. The process according to claim 17, characterized in that the first carrageenan extract is a neutrally extracted carrageenan kappa and the third gelation temperature is from about 10 ° C to about 38 ° C and the third melting temperature is from about 23 ° C to approximately
53 ° C
ES09718931.0T 2008-03-14 2009-03-13 Carrageenan modified by an ion exchange procedure Active ES2358397T3 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US20785808P 2008-03-14 2008-03-14
US20785708P 2008-03-14 2008-03-14
US20785608P 2008-03-14 2008-03-14
US207857 2008-03-14
US207858 2008-03-14
US207856 2008-03-14
US12/403,097 US8293285B2 (en) 2008-03-14 2009-03-12 Carrageenan modified by ion-exchange process
US403097 2009-03-12
PCT/US2009/037047 WO2009114749A2 (en) 2008-03-14 2009-03-13 Carrageenan modified by ion-exchange process

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ES2358397T1 true ES2358397T1 (en) 2011-05-10
ES2358397T3 ES2358397T3 (en) 2015-07-01

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EP (3) EP2910575B1 (en)
JP (3) JP5552064B2 (en)
KR (3) KR101501744B1 (en)
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AR (1) AR079280A1 (en)
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DE (3) DE15159599T1 (en)
DK (3) DK2910575T3 (en)
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JP6689052B2 (en) * 2015-10-02 2020-04-28 帝人ファーマ株式会社 Carrageenan low in divalent cation and method for producing the same
WO2017123851A1 (en) * 2016-01-14 2017-07-20 Fmc Corporation Iota carrageenan - multi-valent cation alginate binder composition
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