ES2349107T8 - Método analítico e instrumento. - Google Patents

Método analítico e instrumento. Download PDF

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Publication number
ES2349107T8
ES2349107T8 ES06026114T ES06026114T ES2349107T8 ES 2349107 T8 ES2349107 T8 ES 2349107T8 ES 06026114 T ES06026114 T ES 06026114T ES 06026114 T ES06026114 T ES 06026114T ES 2349107 T8 ES2349107 T8 ES 2349107T8
Authority
ES
Spain
Prior art keywords
analytical
instrument method
analyte
determination
subjects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06026114T
Other languages
English (en)
Other versions
ES2349107T3 (es
Inventor
Rolf Knobel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Original Assignee
F Hoffmann La Roche AG
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG, Roche Diagnostics GmbH filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2349107T3 publication Critical patent/ES2349107T3/es
Publication of ES2349107T8 publication Critical patent/ES2349107T8/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00693—Calibration
    • G01N2035/00702—Curve-fitting; Parameter matching; Calibration constants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
ES06026114T 2005-12-19 2006-12-16 Método analítico e instrumento. Active ES2349107T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05112359 2005-12-19
EP05112359A EP1798650A1 (en) 2005-12-19 2005-12-19 Analytical method and instrument

Publications (2)

Publication Number Publication Date
ES2349107T3 ES2349107T3 (es) 2010-12-28
ES2349107T8 true ES2349107T8 (es) 2011-02-08

Family

ID=36499040

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06026114T Active ES2349107T3 (es) 2005-12-19 2006-12-16 Método analítico e instrumento.

Country Status (9)

Country Link
US (1) US8239137B2 (es)
EP (2) EP1798650A1 (es)
JP (1) JP4718431B2 (es)
CN (1) CN101037711B (es)
AT (1) ATE479152T1 (es)
CA (1) CA2571454C (es)
DE (1) DE602006016397D1 (es)
ES (1) ES2349107T3 (es)
HK (1) HK1109787A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7680868B2 (en) * 2005-12-20 2010-03-16 Roche Molecular Systems, Inc. PCR elbow determination by use of a double sigmoid function curve fit with the Levenburg-Marquardt algorithm and normalization
CN101688841B (zh) * 2007-06-29 2011-12-07 霍夫曼-拉罗奇有限公司 用于确定pcr和其他数据集中的串扰系数的系统和方法
US20090119020A1 (en) * 2007-09-25 2009-05-07 Roche Molecular Systems, Inc. Pcr elbow determination using quadratic test for curvature analysis of a double sigmoid
JPWO2009054474A1 (ja) * 2007-10-26 2011-03-10 凸版印刷株式会社 アレル判定装置及び方法、ならびに、コンピュータプログラム
US8374795B2 (en) * 2008-05-13 2013-02-12 Roche Molecular Systems, Inc. Systems and methods for step discontinuity removal in real-time PCR fluorescence data
US8285489B2 (en) * 2008-09-09 2012-10-09 Bio-Rad Laboratories, Inc. Multi-stage, regression-based PCR analysis system
CA2756300C (en) * 2009-05-15 2017-11-14 Idaho Technology, Inc. Systems and methods for automated melting curve analysis
US9932628B2 (en) 2012-07-27 2018-04-03 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
EP2719770B1 (en) 2012-10-15 2015-12-30 F. Hoffmann-La Roche AG A method of detecting a presence and/or measuring a quantity of an analyte in a sample by a nucleic acid amplification reaction
CN104854457B (zh) * 2012-12-20 2016-09-14 霍夫曼-拉罗奇有限公司 用于分析体液样本的方法
JP6386031B2 (ja) * 2013-05-15 2018-09-05 ソーン ダイアグノスティックス インコーポレイテッド 核酸増幅信号収集及び信号分析
ES2832544T3 (es) 2014-08-27 2021-06-10 Hoffmann La Roche Un procedimiento de análisis y sistema para analizar una reacción de amplificación de ácido nucleico
US10240836B2 (en) * 2015-06-30 2019-03-26 Emerson Climate Technologies Retail Solutions, Inc. Energy management for refrigeration systems
GB201511587D0 (en) * 2015-07-02 2015-08-19 Ge Healthcare Bio Sciences Ab A method and a system for determining a concentration range for a sample by means of a calibration curve
WO2017052300A1 (en) * 2015-09-24 2017-03-30 Seegene, Inc. . Multiple dataset analysis for determining the presence or absence of target analyte
CN106841133A (zh) * 2016-12-31 2017-06-13 必欧瀚生物技术（合肥）有限公司 一种基于荧光免疫层析技术的定量检测计算方法
EP3432314A1 (en) 2017-07-17 2019-01-23 F. Hoffmann-La Roche AG Techniques for determining coagulation results
KR102420644B1 (ko) * 2017-09-28 2022-07-13 주식회사 씨젠 시료 내 타겟 분석물을 분석하는 방법 및 장치
US20210071242A1 (en) * 2018-01-29 2021-03-11 Gen-Probe Incorporated Analytical systems and methods
CN108387673B (zh) * 2018-03-07 2020-08-14 河南理工大学 一种混合物成分闪速定性识别方法
CN110553989A (zh) * 2019-09-03 2019-12-10 无锡创想分析仪器有限公司 一种去除光谱基线的方法
CN112816446B (zh) * 2020-12-24 2022-02-01 四川长虹电器股份有限公司 一种基于荧光光谱检测荧光轮粉体衰变的方法
JPWO2023132155A1 (es) * 2022-01-05 2023-07-13

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028182A (en) * 1972-11-18 1977-06-07 Canadian Patents And Development Limited Microbiological synthesis of proteinaceous material employing normally gaseous hydrocarbon substrate and the products thereof
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
ES8706823A1 (es) 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5766889A (en) 1994-06-08 1998-06-16 The Perkin-Elmer Corporation Method for determining the characteristics of the concentration growth of target nucleic acid molecules in polymerase chain reaction sample
CA2257109C (en) 1996-06-04 2009-10-06 University Of Utah Research Foundation Monitoring hybridization during pcr
US6303305B1 (en) * 1999-03-30 2001-10-16 Roche Diagnostics, Gmbh Method for quantification of an analyte
US7228237B2 (en) * 2002-02-07 2007-06-05 Applera Corporation Automatic threshold setting and baseline determination for real-time PCR
US7680604B2 (en) 2005-03-11 2010-03-16 Roche Molecular Systems, Inc. PCR elbow determination by rotational transform after zero slope alignment
US7680603B2 (en) * 2005-03-11 2010-03-16 Roche Molecular Systems, Inc. Systems and methods for determining real-time PCR cycle thresholds using a rotation transformation

Also Published As

Publication number Publication date
ATE479152T1 (de) 2010-09-15
US20070166744A1 (en) 2007-07-19
JP4718431B2 (ja) 2011-07-06
EP1798650A1 (en) 2007-06-20
US8239137B2 (en) 2012-08-07
ES2349107T3 (es) 2010-12-28
CA2571454A1 (en) 2007-06-19
HK1109787A1 (en) 2008-06-20
CN101037711B (zh) 2012-04-25
JP2007188484A (ja) 2007-07-26
CA2571454C (en) 2015-01-27
EP1798652B8 (en) 2010-09-29
DE602006016397D1 (de) 2010-10-07
EP1798652A1 (en) 2007-06-20
CN101037711A (zh) 2007-09-19
EP1798652B1 (en) 2010-08-25

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