ES2344631T3 - Composicion analgesica que comprende un opiaceo y un bloqueante de los canales del sodio. - Google Patents
Composicion analgesica que comprende un opiaceo y un bloqueante de los canales del sodio. Download PDFInfo
- Publication number
- ES2344631T3 ES2344631T3 ES02734980T ES02734980T ES2344631T3 ES 2344631 T3 ES2344631 T3 ES 2344631T3 ES 02734980 T ES02734980 T ES 02734980T ES 02734980 T ES02734980 T ES 02734980T ES 2344631 T3 ES2344631 T3 ES 2344631T3
- Authority
- ES
- Spain
- Prior art keywords
- morphine
- opioid
- ttx
- pain
- tetrodotoxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011180986A CN1269482C (zh) | 2001-05-18 | 2001-05-18 | 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用 |
| CN01118098 | 2001-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2344631T3 true ES2344631T3 (es) | 2010-09-02 |
Family
ID=4662967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02734980T Expired - Lifetime ES2344631T3 (es) | 2001-05-18 | 2002-05-20 | Composicion analgesica que comprende un opiaceo y un bloqueante de los canales del sodio. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6780866B2 (https=) |
| EP (1) | EP1387685B1 (https=) |
| JP (1) | JP2004529959A (https=) |
| CN (1) | CN1269482C (https=) |
| AT (1) | ATE464903T1 (https=) |
| CA (1) | CA2485337C (https=) |
| DE (1) | DE60236077D1 (https=) |
| ES (1) | ES2344631T3 (https=) |
| WO (1) | WO2002094272A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1284536C (zh) * | 2000-09-18 | 2006-11-15 | 威克斯医药有限公司 | 河豚毒素或蛤蚌毒素及其类似物在制备用于全身镇痛的镇痛药中的应用 |
| CN1269482C (zh) * | 2001-05-18 | 2006-08-16 | 威克斯医药有限公司 | 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用 |
| MXPA04004543A (es) | 2001-11-15 | 2005-03-31 | Micro Algae Corp | Composiciones farmaceuticas que contienen 3,4-propinoperhidropurinas y sus usos para el bloqueo de la transmision neuronal. |
| CN1568999A (zh) | 2003-07-14 | 2005-01-26 | 南宁枫叶药业有限公司 | 稳定的医药用河豚毒素冷冻干燥制剂 |
| JP2007538010A (ja) * | 2004-05-07 | 2007-12-27 | ファイトトックス リミテッド | フィコトキシンの経皮投与 |
| JP2007536269A (ja) * | 2004-05-07 | 2007-12-13 | ファイトトックス リミテッド | ゴニオトキシンを用いた創傷の治療方法 |
| CN101039675A (zh) * | 2004-09-22 | 2007-09-19 | 埃斯蒂文博士实验室股份有限公司 | 河豚毒素及其衍生物用于治疗外周神经源性神经痛 |
| EP1702627A1 (en) * | 2005-03-18 | 2006-09-20 | Laboratorios Del Dr. Esteve, S.A. | Analgesic combination of sodium channel blockers with opioid antagonists |
| US20100048592A1 (en) * | 2005-08-25 | 2010-02-25 | Wex Pharmaceuticals Inc. | Use of sodium channel blockers for the management of musculoskeletal pain |
| WO2007025212A2 (en) * | 2005-08-25 | 2007-03-01 | Wex Pharmaceuticals, Inc. | Use of sodium channel blockers for the treatment of visceral pain or pain caused by cancer treatment |
| GB0603008D0 (en) * | 2006-02-14 | 2006-03-29 | Portela & Ca Sa | Method |
| ES2691411T3 (es) | 2006-03-27 | 2018-11-27 | Wex Medical Limited | Uso de bloqueadores de los canales de sodio para el tratamiento del dolor neuropático que se desarrolla como consecuencia de la quimioterapia |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022899A (en) | 1973-06-12 | 1977-05-10 | Astra Pharmaceutical Products, Inc. | Synergistic local anesthetic compositions |
| US4906779A (en) * | 1986-07-10 | 1990-03-06 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists |
| US5262568A (en) * | 1990-03-02 | 1993-11-16 | State Of Oregon | Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists |
| WO1993013128A1 (en) * | 1991-12-30 | 1993-07-08 | Neurex Corporation | Methods of producing analgesia and enhancing opiate analgesia |
| NZ268969A (en) | 1993-07-23 | 1997-06-24 | Toray Industries | Morphinan derivatives and pharmaceutical compositions |
| WO1995023132A1 (en) * | 1994-02-23 | 1995-08-31 | Cambridge Neuroscience, Inc. | Blockers of ion channels and methods of use thereof |
| AU1888195A (en) * | 1994-03-17 | 1995-10-03 | Nanning Maple Leaf Pharmaceutical Co. Ltd. | The use of amino hydrogenated quinazoline compounds and derivatives thereof for abstaining from drug dependence |
| GB9513180D0 (en) * | 1995-06-28 | 1995-08-30 | Univ London | Ion channel |
| DE19602970A1 (de) | 1995-12-20 | 1997-07-31 | Nycomed Arzneimittel Gmbh | Neue 7,8- Dihydromorphinderivate, Verfahren zu deren Herstellung und deren Verwendung |
| CN1072486C (zh) * | 1996-09-24 | 2001-10-10 | 王维国 | 用于戒毒、镇痛的药剂及其制法 |
| CN1081034C (zh) * | 1997-03-07 | 2002-03-20 | 潘心富 | 一种双胍基氢化嘌呤环类化合物的戒毒药 |
| WO1998043619A2 (en) * | 1997-04-02 | 1998-10-08 | The Regents Of The University Of California | Method of local anesthesia |
| AU7389098A (en) * | 1997-05-16 | 1998-12-08 | Brigham And Women's Hospital | Local anesthetic formulations |
| DE19936719A1 (de) * | 1999-08-06 | 2001-02-15 | Gruenenthal Gmbh | Substituierte 1,5-Dihydropyrrol-2-on-Derivate |
| CN1284536C (zh) | 2000-09-18 | 2006-11-15 | 威克斯医药有限公司 | 河豚毒素或蛤蚌毒素及其类似物在制备用于全身镇痛的镇痛药中的应用 |
| CN1203857C (zh) * | 2000-09-18 | 2005-06-01 | 威克斯医药有限公司 | 局部麻醉与镇痛的新方法 |
| CN1236773C (zh) * | 2000-11-22 | 2006-01-18 | 南宁枫叶药业有限公司 | 用于镇痛、麻醉或治疗药物依赖性的制剂 |
| CN1269482C (zh) * | 2001-05-18 | 2006-08-16 | 威克斯医药有限公司 | 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用 |
-
2001
- 2001-05-18 CN CNB011180986A patent/CN1269482C/zh not_active Expired - Fee Related
-
2002
- 2002-02-05 US US10/062,483 patent/US6780866B2/en not_active Expired - Fee Related
- 2002-05-20 DE DE60236077T patent/DE60236077D1/de not_active Expired - Lifetime
- 2002-05-20 WO PCT/CN2002/000339 patent/WO2002094272A1/en not_active Ceased
- 2002-05-20 ES ES02734980T patent/ES2344631T3/es not_active Expired - Lifetime
- 2002-05-20 CA CA002485337A patent/CA2485337C/en not_active Expired - Fee Related
- 2002-05-20 EP EP02734980A patent/EP1387685B1/en not_active Expired - Lifetime
- 2002-05-20 AT AT02734980T patent/ATE464903T1/de not_active IP Right Cessation
- 2002-05-20 JP JP2002590989A patent/JP2004529959A/ja active Pending
-
2004
- 2004-05-20 US US10/849,240 patent/US20040214842A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040214842A1 (en) | 2004-10-28 |
| CN1386505A (zh) | 2002-12-25 |
| DE60236077D1 (de) | 2010-06-02 |
| JP2004529959A (ja) | 2004-09-30 |
| EP1387685A1 (en) | 2004-02-11 |
| EP1387685B1 (en) | 2010-04-21 |
| CN1269482C (zh) | 2006-08-16 |
| US6780866B2 (en) | 2004-08-24 |
| US20020198226A1 (en) | 2002-12-26 |
| CA2485337C (en) | 2007-08-28 |
| WO2002094272A1 (en) | 2002-11-28 |
| CA2485337A1 (en) | 2002-11-28 |
| EP1387685A4 (en) | 2007-05-23 |
| ATE464903T1 (de) | 2010-05-15 |
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