ES2291197T3 - Analogos de flint resistentes a proteasas. - Google Patents
Analogos de flint resistentes a proteasas. Download PDFInfo
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- ES2291197T3 ES2291197T3 ES00916264T ES00916264T ES2291197T3 ES 2291197 T3 ES2291197 T3 ES 2291197T3 ES 00916264 T ES00916264 T ES 00916264T ES 00916264 T ES00916264 T ES 00916264T ES 2291197 T3 ES2291197 T3 ES 2291197T3
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- 229940080469 phosphocellulose Drugs 0.000 description 1
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- 229910052709 silver Inorganic materials 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007974 sodium acetate buffer Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
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- 150000003522 tetracyclines Chemical class 0.000 description 1
- 125000003831 tetrazolyl group Chemical group 0.000 description 1
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- 150000003588 threonines Chemical class 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Obesity (AREA)
- Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12683999P | 1999-03-30 | 1999-03-30 | |
| US126839P | 1999-03-30 | ||
| US14007399P | 1999-06-21 | 1999-06-21 | |
| US140073P | 1999-06-21 | ||
| US14707199P | 1999-08-04 | 1999-08-04 | |
| US147071P | 1999-08-04 | ||
| US16052499P | 1999-10-20 | 1999-10-20 | |
| US160524P | 1999-10-20 | ||
| US16066999P | 1999-10-21 | 1999-10-21 | |
| US160669P | 1999-10-21 | ||
| US17274499P | 1999-12-20 | 1999-12-20 | |
| US172744P | 1999-12-20 | ||
| US17818400P | 2000-01-26 | 2000-01-26 | |
| US178184P | 2000-01-26 | ||
| PCT/US2000/006418 WO2000058466A2 (en) | 1999-03-30 | 2000-03-20 | Protease resistant flint analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2291197T3 true ES2291197T3 (es) | 2008-03-01 |
Family
ID=27568834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00916264T Expired - Lifetime ES2291197T3 (es) | 1999-03-30 | 2000-03-20 | Analogos de flint resistentes a proteasas. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1165781B1 (enExample) |
| JP (1) | JP4590504B2 (enExample) |
| AT (1) | ATE371737T1 (enExample) |
| AU (1) | AU3739500A (enExample) |
| CA (1) | CA2368767C (enExample) |
| DE (1) | DE60036199T2 (enExample) |
| ES (1) | ES2291197T3 (enExample) |
| WO (1) | WO2000058466A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
| CA2277925A1 (en) | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6.alpha. and 6.beta. |
| ATE393222T1 (de) | 1997-09-18 | 2008-05-15 | Genentech Inc | Dcr3 polypeptid, ein tnfr homolog |
| JP2002539828A (ja) * | 1999-03-30 | 2002-11-26 | イーライ・リリー・アンド・カンパニー | Ｆｌｉｎｔポリペプチドアナログ |
| WO2001028582A2 (en) * | 1999-10-20 | 2001-04-26 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
| EP1355945A2 (en) * | 2001-02-01 | 2003-10-29 | Eli Lilly And Company | Flint glycoforms |
| AU2002246967A1 (en) * | 2001-02-01 | 2002-08-12 | Eli Lilly And Company | Glycoforms a fas ligand inhibitory protein analog |
| EP1447093A1 (en) | 2003-02-14 | 2004-08-18 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Inhibition of the CD95 ligand/receptor system for the treatment of neurological disorders and injuries |
| EP3846829A4 (en) * | 2018-09-05 | 2022-09-14 | Arizona Board of Regents on behalf of Arizona State University | ONCOLYTIC VIRUS PLATFORM FOR THE TREATMENT OF HEMATOLOGICAL CANCER |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2277925A1 (en) * | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6.alpha. and 6.beta. |
| ATE393222T1 (de) * | 1997-09-18 | 2008-05-15 | Genentech Inc | Dcr3 polypeptid, ein tnfr homolog |
| CA2324517A1 (en) * | 1998-03-30 | 1999-10-07 | Eli Lilly And Company | Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily |
-
2000
- 2000-03-20 AT AT00916264T patent/ATE371737T1/de not_active IP Right Cessation
- 2000-03-20 EP EP00916264A patent/EP1165781B1/en not_active Expired - Lifetime
- 2000-03-20 WO PCT/US2000/006418 patent/WO2000058466A2/en not_active Ceased
- 2000-03-20 CA CA002368767A patent/CA2368767C/en not_active Expired - Fee Related
- 2000-03-20 AU AU37395/00A patent/AU3739500A/en not_active Abandoned
- 2000-03-20 JP JP2000608747A patent/JP4590504B2/ja not_active Expired - Fee Related
- 2000-03-20 ES ES00916264T patent/ES2291197T3/es not_active Expired - Lifetime
- 2000-03-20 DE DE60036199T patent/DE60036199T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2368767A1 (en) | 2000-10-05 |
| JP2002539829A (ja) | 2002-11-26 |
| ATE371737T1 (de) | 2007-09-15 |
| EP1165781B1 (en) | 2007-08-29 |
| WO2000058466A2 (en) | 2000-10-05 |
| JP4590504B2 (ja) | 2010-12-01 |
| AU3739500A (en) | 2000-10-16 |
| WO2000058466A3 (en) | 2001-01-11 |
| DE60036199T2 (de) | 2008-05-21 |
| EP1165781A2 (en) | 2002-01-02 |
| CA2368767C (en) | 2008-12-30 |
| DE60036199D1 (de) | 2007-10-11 |
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