ES2290046T3 - Procedimiento para caracterizar un estado biologico, mediante el empleo de perfiles calibrados de expresion genica. - Google Patents
Procedimiento para caracterizar un estado biologico, mediante el empleo de perfiles calibrados de expresion genica. Download PDFInfo
- Publication number
- ES2290046T3 ES2290046T3 ES00944977T ES00944977T ES2290046T3 ES 2290046 T3 ES2290046 T3 ES 2290046T3 ES 00944977 T ES00944977 T ES 00944977T ES 00944977 T ES00944977 T ES 00944977T ES 2290046 T3 ES2290046 T3 ES 2290046T3
- Authority
- ES
- Spain
- Prior art keywords
- profile data
- calibrated
- panel
- sample
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Zoology (AREA)
- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14154299P | 1999-06-28 | 1999-06-28 | |
| US141542P | 1999-06-28 | ||
| US19552200P | 2000-04-07 | 2000-04-07 | |
| US195522P | 2000-04-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2290046T3 true ES2290046T3 (es) | 2008-02-16 |
Family
ID=26839213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00944977T Expired - Lifetime ES2290046T3 (es) | 1999-06-28 | 2000-06-28 | Procedimiento para caracterizar un estado biologico, mediante el empleo de perfiles calibrados de expresion genica. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1198585B1 (https=) |
| JP (1) | JP2004528526A (https=) |
| KR (1) | KR20020079364A (https=) |
| AT (1) | ATE364721T1 (https=) |
| AU (1) | AU784233B2 (https=) |
| CA (1) | CA2378008A1 (https=) |
| CY (1) | CY1107733T1 (https=) |
| DE (1) | DE60035196T2 (https=) |
| DK (1) | DK1198585T3 (https=) |
| ES (1) | ES2290046T3 (https=) |
| IL (2) | IL147349A0 (https=) |
| PT (1) | PT1198585E (https=) |
| WO (1) | WO2001025473A1 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7473528B2 (en) | 1999-01-06 | 2009-01-06 | Genenews Inc. | Method for the detection of Chagas disease related gene transcripts in blood |
| US6960439B2 (en) | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US7590493B2 (en) | 2000-07-31 | 2009-09-15 | Ocimum Biosolutions, Inc. | Methods for determining hepatotoxins |
| AUPR480901A0 (en) * | 2001-05-04 | 2001-05-31 | Genomics Research Partners Pty Ltd | Diagnostic method for assessing a condition of a performance animal |
| EP1392871A4 (en) * | 2001-05-22 | 2006-04-19 | Gene Logic Inc | MODELING MOLECULAR TOXICITY |
| US7026121B1 (en) | 2001-06-08 | 2006-04-11 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US20030096264A1 (en) * | 2001-06-18 | 2003-05-22 | Psychiatric Genomics, Inc. | Multi-parameter high throughput screening assays (MPHTS) |
| US7447594B2 (en) | 2001-07-10 | 2008-11-04 | Ocimum Biosolutions, Inc. | Molecular cardiotoxicology modeling |
| AU2002365904A1 (en) * | 2001-07-10 | 2003-09-04 | Gene Logic, Inc. | Cardiotoxin molecular toxicology modeling |
| EP2277991A1 (en) * | 2001-08-21 | 2011-01-26 | Ventana Medical Systems, Inc. | Method and quantification assay for determining c-kit/SCF/pAKT status |
| CN1612936A (zh) | 2001-11-09 | 2005-05-04 | 苏尔斯精细医药公司 | 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态 |
| US7469185B2 (en) | 2002-02-04 | 2008-12-23 | Ocimum Biosolutions, Inc. | Primary rat hepatocyte toxicity modeling |
| US7662594B2 (en) | 2002-09-20 | 2010-02-16 | New England Biolabs, Inc. | Helicase-dependent amplification of RNA |
| JP4632788B2 (ja) | 2002-09-20 | 2011-02-16 | ニュー・イングランド・バイオラブズ・インコーポレイティッド | 核酸のヘリカーゼ依存性増幅 |
| AU2002952696A0 (en) * | 2002-11-14 | 2002-11-28 | Genomics Research Partners Pty Ltd | Status determination |
| US7778782B1 (en) | 2002-12-17 | 2010-08-17 | Entelos, Inc. | Peroxisome proliferation activated receptor alpha (PPARα) signatures |
| US7396645B1 (en) | 2002-12-17 | 2008-07-08 | Entelos, Inc. | Cholestasis signature |
| WO2004057034A1 (en) * | 2002-12-19 | 2004-07-08 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of infectious disease and characterization of inflammatory conditions related to infectious disease using gene expression profiles |
| US7422854B1 (en) | 2002-12-20 | 2008-09-09 | Entelos, Inc. | Cholesterol reduction signature |
| US7519519B1 (en) | 2002-12-20 | 2009-04-14 | Entelos, Inc. | Signature projection score |
| AU2003901196A0 (en) * | 2003-03-17 | 2003-04-03 | Commonwealth Scientific And Industrial Research Organisation | Analysis method |
| EP1668111A4 (en) | 2003-08-08 | 2008-07-02 | Genenews Inc | OSTEOARTHRITIS BIOMARKERS AND USES THEREOF |
| JPWO2005087924A1 (ja) * | 2004-02-18 | 2008-01-31 | 株式会社三重ティーエルオー | Dnaチップ並びに疾患関連遺伝子の抽出方法 |
| EP2062981B1 (en) | 2005-06-16 | 2013-09-25 | Life Technologies Corporation | Gene expression profiling for identification and monitoring of multiple sclerosis |
| AU2006294477A1 (en) | 2005-09-27 | 2007-04-05 | Source Mdx | Gene expression profiling for identification monitoring and treatment of rheumatoid arthritis |
| AU2007254206A1 (en) * | 2006-05-16 | 2007-11-29 | Source Mdx | Assessment of effect of an agent on a human biological condition using rodent gene expression panels |
| US20100196889A1 (en) | 2006-11-13 | 2010-08-05 | Bankaitis-Davis Danute M | Gene Expression Profiling for Identification, Monitoring and Treatment of Colorectal Cancer |
| EP2315858A2 (en) | 2008-07-08 | 2011-05-04 | Source Precision Medicine, Inc. | Gene expression profiling for predicting the survivability of prostate cancer subjects |
| NZ593854A (en) | 2009-01-06 | 2013-02-22 | Source Prec Medicine Inc D B A Source Mdx | Gene expression profiling for the identification, monitoring, and treatment of prostate cancer |
| US9074248B1 (en) | 2012-12-18 | 2015-07-07 | Qiagen Gmbh | Primers for helicase dependent amplification and their methods of use |
| CN103525926B (zh) * | 2013-10-08 | 2016-03-23 | 浙江大学 | 一种基于基因表达谱的药物毒性个体易感性基因标志物的筛选方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5643765A (en) * | 1993-04-06 | 1997-07-01 | University Of Rochester | Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction |
| US5922184A (en) * | 1997-07-21 | 1999-07-13 | Bio-Rad Laboratories, Inc. | Computer-directed detection of paraproteins |
| EP0960214A4 (en) * | 1996-12-06 | 2004-08-04 | Urocor Inc | Diagnosis of disease status on HAnd from mRNA profiles |
| US5968784A (en) * | 1997-01-15 | 1999-10-19 | Chugai Pharmaceutical Co., Ltd. | Method for analyzing quantitative expression of genes |
| GB9704444D0 (en) * | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
| WO1999011822A1 (en) * | 1997-09-03 | 1999-03-11 | Gene Logic Inc. | Method for predicting prognosis and treatment response for genetically based abnormalities |
| US6461817B1 (en) * | 1997-09-12 | 2002-10-08 | The Public Health Research Institute Of The City Of New York | Non-competitive co-amplification methods |
| EP1027456B1 (en) * | 1997-10-31 | 2005-03-16 | Affymetrix, Inc. (a Delaware Corporation) | Expression profiles in adult and fetal organs |
-
2000
- 2000-06-28 ES ES00944977T patent/ES2290046T3/es not_active Expired - Lifetime
- 2000-06-28 WO PCT/US2000/017846 patent/WO2001025473A1/en not_active Ceased
- 2000-06-28 AU AU58985/00A patent/AU784233B2/en not_active Expired
- 2000-06-28 IL IL14734900A patent/IL147349A0/xx unknown
- 2000-06-28 CA CA002378008A patent/CA2378008A1/en not_active Abandoned
- 2000-06-28 KR KR1020017016828A patent/KR20020079364A/ko not_active Ceased
- 2000-06-28 AT AT00944977T patent/ATE364721T1/de active
- 2000-06-28 DE DE60035196T patent/DE60035196T2/de not_active Revoked
- 2000-06-28 DK DK00944977T patent/DK1198585T3/da active
- 2000-06-28 PT PT00944977T patent/PT1198585E/pt unknown
- 2000-06-28 JP JP2001528624A patent/JP2004528526A/ja active Pending
- 2000-06-28 EP EP00944977A patent/EP1198585B1/en not_active Revoked
-
2001
- 2001-12-26 IL IL147349A patent/IL147349A/en active IP Right Grant
-
2007
- 2007-09-12 CY CY20071101178T patent/CY1107733T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1198585B1 (en) | 2007-06-13 |
| AU784233B2 (en) | 2006-02-23 |
| ATE364721T1 (de) | 2007-07-15 |
| AU5898500A (en) | 2001-05-10 |
| DK1198585T3 (da) | 2007-10-15 |
| JP2004528526A (ja) | 2004-09-16 |
| DE60035196T2 (de) | 2008-02-21 |
| KR20020079364A (ko) | 2002-10-19 |
| CY1107733T1 (el) | 2013-04-18 |
| PT1198585E (pt) | 2007-09-20 |
| IL147349A0 (en) | 2002-08-14 |
| EP1198585A1 (en) | 2002-04-24 |
| WO2001025473A9 (en) | 2002-08-08 |
| IL147349A (en) | 2011-12-29 |
| DE60035196D1 (de) | 2007-07-26 |
| CA2378008A1 (en) | 2001-04-12 |
| WO2001025473A1 (en) | 2001-04-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2290046T3 (es) | Procedimiento para caracterizar un estado biologico, mediante el empleo de perfiles calibrados de expresion genica. | |
| Wienke | Frailty models in survival analysis | |
| Slonim et al. | Getting started in gene expression microarray analysis | |
| EP1451340A1 (en) | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles | |
| US20040219568A1 (en) | Systems and methods for characterizing a biological conditions or agent using selected gene expression profiles | |
| Shaffer et al. | A comparison of DNA/RNA extraction protocols for high-throughput sequencing of microbial communities | |
| EP2066809A2 (en) | Gene expression profiling for identification, monitoring and treatment of transplant rejection | |
| JP2010227111A (ja) | 遺伝子発現プロフィールを用いる、感染症の同定、モニタリング、および処置、ならびに感染症に関連する炎症状態の特徴付け | |
| JP2005508505A5 (https=) | ||
| JP7141029B2 (ja) | データベースを構築する方法 | |
| Mistry et al. | Ventricular-subventricular zone contact by glioblastoma is not associated with molecular signatures in bulk tumor data | |
| WO2009158513A1 (en) | Gene expression profiling for identification, monitoring, and treatment of osteoarthritis | |
| AU2003303238A2 (en) | Identification, monitoring and treatment of infectious disease and characterization of inflammatory conditions related to infectious disease using gene expression profiles | |
| JP2006510382A5 (https=) | ||
| Sutherland et al. | Canadian lung tissue biobank with associated clinical data supporting respiratory research for four decades | |
| Xunlu et al. | Integrative bioinformatics analysis reveals potential gene biomarkers and analysis of function in human degenerative disc annulus fibrosus cells | |
| North | The global alliance for genomics and health: towards international sharing of genomic and clinical data | |
| Marine et al. | Cell position matters in tumour development | |
| Zapotocky et al. | Gene-14. Unique molecular and clinical features of Li-Fraumeni syndrome associated brain tumours | |
| Chowdhury et al. | Protein-Protein Interaction Network and Novel Biomarkers of Celiac Disease | |
| Karvonen et al. | GENE-17. Tumor-derived cell-free DNA may be frequently detected by clinical targeted sequencing of cerebrospinal fluid in children with brain tumors | |
| Eriksen | What are the Prospects for-Omics-Based Molecular Technologies in Cancer Diagnostics and Treatment | |
| Xu et al. | Pathway cross-talk analysis in detecting significant pathways in Barrett’s esophagus patients | |
| HK1169190A (en) | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles | |
| Dolci et al. | P255 Avascular osteonecrosis of the jawbones in oncological patients related to the use of bisphophonates: the role of a correct diagnosis as the first step of the treatement planning |