ES2260080T3 - Proteinas histono deacetilasa-8, acidos nucleicos y procedimiento de utilizacion. - Google Patents

Proteinas histono deacetilasa-8, acidos nucleicos y procedimiento de utilizacion.

Info

Publication number
ES2260080T3
ES2260080T3 ES00982576T ES00982576T ES2260080T3 ES 2260080 T3 ES2260080 T3 ES 2260080T3 ES 00982576 T ES00982576 T ES 00982576T ES 00982576 T ES00982576 T ES 00982576T ES 2260080 T3 ES2260080 T3 ES 2260080T3
Authority
ES
Spain
Prior art keywords
hdac8
protein
cell
cells
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00982576T
Other languages
English (en)
Spanish (es)
Inventor
Joseph Buggy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axys Pharmaceuticals Inc
Original Assignee
Axys Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axys Pharmaceuticals Inc filed Critical Axys Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2260080T3 publication Critical patent/ES2260080T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES00982576T 1999-12-08 2000-12-08 Proteinas histono deacetilasa-8, acidos nucleicos y procedimiento de utilizacion. Expired - Lifetime ES2260080T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16972399P 1999-12-08 1999-12-08
US169723P 1999-12-08

Publications (1)

Publication Number Publication Date
ES2260080T3 true ES2260080T3 (es) 2006-11-01

Family

ID=22616924

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00982576T Expired - Lifetime ES2260080T3 (es) 1999-12-08 2000-12-08 Proteinas histono deacetilasa-8, acidos nucleicos y procedimiento de utilizacion.

Country Status (8)

Country Link
EP (1) EP1246905B1 (enExample)
JP (2) JP2003516144A (enExample)
AT (1) ATE320484T1 (enExample)
AU (1) AU1959001A (enExample)
CA (1) CA2393725A1 (enExample)
DE (1) DE60026733T2 (enExample)
ES (1) ES2260080T3 (enExample)
WO (1) WO2001042437A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001042437A2 (en) * 1999-12-08 2001-06-14 Axys Pharmaceuticals, Inc. Histone deacetylase-8 proteins, nucleic acids, and methods of use
PE20020354A1 (es) 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
US7063973B2 (en) 2001-06-14 2006-06-20 Sloan-Kettering Institute For Cancer Research HDAC9 polypeptides and polynucleotides and uses thereof
EP1407049A4 (en) * 2001-06-19 2005-03-23 David Gladstone Inst HISTON DEACETYLASE AND METHOD OF USE THEREOF
US6706686B2 (en) 2001-09-27 2004-03-16 The Regents Of The University Of Colorado Inhibition of histone deacetylase as a treatment for cardiac hypertrophy
GB0123664D0 (en) 2001-10-02 2001-11-21 Inst Of Cancer Res The Histone deacetylase 9
JP4638148B2 (ja) 2001-10-16 2011-02-23 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ 神経変性疾患および脳の癌の処置
US7154002B1 (en) 2002-10-08 2006-12-26 Takeda San Diego, Inc. Histone deacetylase inhibitors
US7250514B1 (en) 2002-10-21 2007-07-31 Takeda San Diego, Inc. Histone deacetylase inhibitors
GB0226855D0 (en) 2002-11-18 2002-12-24 Queen Mary & Westfield College Histone deacetylase inhibitors
CA2518318A1 (en) 2003-03-17 2004-09-30 Takeda San Diego, Inc. Histone deacetylase inhibitors
WO2006012222A2 (en) 2004-06-25 2006-02-02 The J. David Gladstone Institutes Methods of treating smooth muscle cell disorders
EP1824831A2 (en) 2004-12-16 2007-08-29 Takeda San Diego, Inc. Histone deacetylase inhibitors
JP2008540574A (ja) 2005-05-11 2008-11-20 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼ阻害剤
CN101263121A (zh) 2005-07-14 2008-09-10 塔克达圣地亚哥公司 组蛋白脱乙酰基酶抑制剂
GB0620823D0 (en) 2006-10-19 2006-11-29 Univ London Histone deacetylase inhibitors
EP3035924A4 (en) * 2013-08-20 2017-04-19 City of Hope Hdac8 inhibitors for treating cancer
EP3470536A1 (en) 2013-10-01 2019-04-17 The J. David Gladstone Institutes Compositions, systems and methods for gene expression noise drug screening and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002523029A (ja) * 1998-08-21 2002-07-30 スミスクライン ビーチャム コーポレーション ヒトヒストンデアセチラーゼ遺伝子ｈｄ４
WO2001042437A2 (en) * 1999-12-08 2001-06-14 Axys Pharmaceuticals, Inc. Histone deacetylase-8 proteins, nucleic acids, and methods of use

Also Published As

Publication number Publication date
EP1246905B1 (en) 2006-03-15
EP1246905A2 (en) 2002-10-09
JP2011182800A (ja) 2011-09-22
WO2001042437A3 (en) 2002-01-10
AU1959001A (en) 2001-06-18
ATE320484T1 (de) 2006-04-15
DE60026733D1 (de) 2006-05-11
DE60026733T2 (de) 2006-11-02
JP2003516144A (ja) 2003-05-13
CA2393725A1 (en) 2001-06-14
WO2001042437A2 (en) 2001-06-14

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