ES2210219T3 - Derivados de octahidro-2h-pirido- (1,2-a) -pirazina, su procedimiento de preparacion y las composiciones farmaceuticas que lo contienen. - Google Patents

Derivados de octahidro-2h-pirido- (1,2-a) -pirazina, su procedimiento de preparacion y las composiciones farmaceuticas que lo contienen.

Info

Publication number
ES2210219T3
ES2210219T3 ES02291745T ES02291745T ES2210219T3 ES 2210219 T3 ES2210219 T3 ES 2210219T3 ES 02291745 T ES02291745 T ES 02291745T ES 02291745 T ES02291745 T ES 02291745T ES 2210219 T3 ES2210219 T3 ES 2210219T3
Authority
ES
Spain
Prior art keywords
formula
compounds
pyrido
octahydro
linear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02291745T
Other languages
English (en)
Spanish (es)
Inventor
Solo Goldstein
Guillaume Poissonnet
Jean-Gilles Parmentier
Pierre Lestage
Brian Lockhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Application granted granted Critical
Publication of ES2210219T3 publication Critical patent/ES2210219T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES02291745T 2001-07-12 2002-07-11 Derivados de octahidro-2h-pirido- (1,2-a) -pirazina, su procedimiento de preparacion y las composiciones farmaceuticas que lo contienen. Expired - Lifetime ES2210219T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0109260 2001-07-12
FR0109260A FR2827288B1 (fr) 2001-07-12 2001-07-12 Nouveaux derives d'octahydro-2h-pyrido[1,2-a]pyrazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2210219T3 true ES2210219T3 (es) 2004-07-01

Family

ID=8865405

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02291745T Expired - Lifetime ES2210219T3 (es) 2001-07-12 2002-07-11 Derivados de octahidro-2h-pirido- (1,2-a) -pirazina, su procedimiento de preparacion y las composiciones farmaceuticas que lo contienen.

Country Status (24)

Country Link
US (1) US6992085B2 (enEXAMPLES)
EP (1) EP1275647B1 (enEXAMPLES)
JP (1) JP3950018B2 (enEXAMPLES)
KR (1) KR100485020B1 (enEXAMPLES)
CN (1) CN1197863C (enEXAMPLES)
AR (1) AR036166A1 (enEXAMPLES)
AT (1) ATE254124T1 (enEXAMPLES)
AU (1) AU2002300094B2 (enEXAMPLES)
BR (1) BR0202681A (enEXAMPLES)
CA (1) CA2394027C (enEXAMPLES)
DE (1) DE60200089T2 (enEXAMPLES)
DK (1) DK1275647T3 (enEXAMPLES)
EA (1) EA005160B1 (enEXAMPLES)
ES (1) ES2210219T3 (enEXAMPLES)
FR (1) FR2827288B1 (enEXAMPLES)
HU (1) HUP0202282A3 (enEXAMPLES)
MX (1) MXPA02006699A (enEXAMPLES)
NO (1) NO322966B1 (enEXAMPLES)
NZ (1) NZ520120A (enEXAMPLES)
PL (1) PL355034A1 (enEXAMPLES)
PT (1) PT1275647E (enEXAMPLES)
SI (1) SI1275647T1 (enEXAMPLES)
TR (1) TR200302001T4 (enEXAMPLES)
ZA (1) ZA200205596B (enEXAMPLES)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1611902A4 (en) * 2003-04-03 2006-04-12 Kyowa Hakko Kogyo Kk MEANS FOR THE PREVENTION AND / OR TREATMENT OF NEUROPATHIC PAIN
MY141255A (en) * 2003-12-11 2010-03-31 Memory Pharm Corp Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2008503560A (ja) * 2004-06-22 2008-02-07 ファイザー・プロダクツ・インク ジアザビシクロ系のヒスタミン−３受容体アンタゴニスト
AU2006264966B2 (en) * 2005-07-04 2013-02-21 High Point Pharmaceuticals, Llc Histamine H3 receptor antagonists
RU2442775C2 (ru) * 2005-07-04 2012-02-20 Хай Пойнт Фармасьютикалс, ЛЛС Антагонисты гистаминовых н3-рецепторов
DE602007011904D1 (de) * 2006-03-10 2011-02-24 Neurogen Corp Piperazinyl-oxoalkyl-tetrahydroisochinoline und verwandte analoga
KR100871691B1 (ko) 2006-10-16 2008-12-05 삼성전자주식회사 병렬 비트 테스트 방법 및 그 방법을 사용하는 반도체메모리 장치
US10870660B2 (en) 2016-07-28 2020-12-22 Shionogi & Co., Ltd. Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect
CN111801330B (zh) 2018-01-26 2024-04-05 盐野义制药株式会社 具有多巴胺d3受体拮抗作用的稠环化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388128A (en) * 1965-09-03 1968-06-11 Allan R. Day Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
GB8518236D0 (en) * 1985-07-19 1985-08-29 Beecham Group Plc Compounds
WO1994006794A1 (en) * 1992-09-24 1994-03-31 National Institutes Of Health Aralkyl diazabicycloalkane derivatives for cns disorders
WO1996010570A1 (en) * 1994-09-30 1996-04-11 Pfizer Inc. NEUROLEPTIC 2,7-DISUBSTITUTED PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES
US6231833B1 (en) * 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
ES2274795T3 (es) * 1999-07-19 2007-06-01 Merck Frosst Canada Ltd. Pirazinonas, composiciones que contienen tales compuestos.

Also Published As

Publication number Publication date
DE60200089T2 (de) 2004-09-09
NO20023345L (no) 2003-01-13
DE60200089D1 (de) 2003-12-18
HUP0202282A2 (hu) 2003-03-28
NZ520120A (en) 2004-03-26
BR0202681A (pt) 2003-05-06
CN1197863C (zh) 2005-04-20
JP2003064081A (ja) 2003-03-05
EA005160B1 (ru) 2004-12-30
US20030195216A1 (en) 2003-10-16
EA200200663A1 (ru) 2003-02-27
MXPA02006699A (es) 2005-08-16
PL355034A1 (en) 2003-01-13
US6992085B2 (en) 2006-01-31
NO322966B1 (no) 2006-12-18
JP3950018B2 (ja) 2007-07-25
EP1275647B1 (fr) 2003-11-12
HK1050682A1 (en) 2003-07-04
KR100485020B1 (ko) 2005-04-25
PT1275647E (pt) 2004-03-31
ATE254124T1 (de) 2003-11-15
EP1275647A1 (fr) 2003-01-15
CA2394027C (fr) 2008-01-08
KR20030007159A (ko) 2003-01-23
HUP0202282A3 (en) 2003-11-28
TR200302001T4 (tr) 2004-01-21
DK1275647T3 (da) 2004-03-15
FR2827288B1 (fr) 2003-10-31
SI1275647T1 (en) 2004-02-29
CA2394027A1 (fr) 2003-01-12
AU2002300094B2 (en) 2007-06-14
FR2827288A1 (fr) 2003-01-17
CN1397557A (zh) 2003-02-19
NO20023345D0 (no) 2002-07-11
AR036166A1 (es) 2004-08-18
HU0202282D0 (enEXAMPLES) 2002-09-28
ZA200205596B (en) 2003-03-27

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