ES2196823T3 - Composicion farmaceutica destinada principalmente a la prevencion y al tratamiento de las radiomucitis y de las mucitis inducidas por las quimioterapias. - Google Patents

Composicion farmaceutica destinada principalmente a la prevencion y al tratamiento de las radiomucitis y de las mucitis inducidas por las quimioterapias.

Info

Publication number
ES2196823T3
ES2196823T3 ES99929503T ES99929503T ES2196823T3 ES 2196823 T3 ES2196823 T3 ES 2196823T3 ES 99929503 T ES99929503 T ES 99929503T ES 99929503 T ES99929503 T ES 99929503T ES 2196823 T3 ES2196823 T3 ES 2196823T3
Authority
ES
Spain
Prior art keywords
induced
pharmaceutical composition
radiomucitis
mucitis
chemotherapies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99929503T
Other languages
English (en)
Inventor
Jerome Besse
Tham Nguyen
Joelle Leyder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of ES2196823T3 publication Critical patent/ES2196823T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Composición farmacéutica destinada a adherirse a una mucosa principalmente para la prevención y el tratamiento de las radiomucitis, y de las quimiomucitis inducidas por la radioterapia y la radioquimioterapia combinada, comprendiendo una cantidad eficaz de un compuesto seleccionado entre los flavonoides y los isoflavonoides en mezcla con un vehículo que es líquido a la temperatura ambiente y se gelifica a la temperatura de la mucosa y que es capaz de adherirse a la mucosa en razón de su estado gelificado.
ES99929503T 1998-07-20 1999-07-19 Composicion farmaceutica destinada principalmente a la prevencion y al tratamiento de las radiomucitis y de las mucitis inducidas por las quimioterapias. Expired - Lifetime ES2196823T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9809230A FR2781156B1 (fr) 1998-07-20 1998-07-20 Composition pharmaceutique destinee notamment a la prevention et au traitement des radiomucites et des chimiomucites

Publications (1)

Publication Number Publication Date
ES2196823T3 true ES2196823T3 (es) 2003-12-16

Family

ID=9528788

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99929503T Expired - Lifetime ES2196823T3 (es) 1998-07-20 1999-07-19 Composicion farmaceutica destinada principalmente a la prevencion y al tratamiento de las radiomucitis y de las mucitis inducidas por las quimioterapias.

Country Status (13)

Country Link
US (1) US7033606B1 (es)
EP (1) EP1098631B1 (es)
JP (1) JP2002521321A (es)
CN (1) CN1149977C (es)
AT (1) ATE235226T1 (es)
AU (1) AU4629699A (es)
CA (1) CA2337152C (es)
DE (1) DE69906302T2 (es)
DK (1) DK1098631T3 (es)
ES (1) ES2196823T3 (es)
FR (1) FR2781156B1 (es)
PT (1) PT1098631E (es)
WO (1) WO2000004878A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE363902T1 (de) 2000-06-14 2007-06-15 Us Health Isoflavonen gegen strahlungsinduzierte mortalität
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
DE60117043T2 (de) * 2000-11-22 2006-07-13 Rxkinetix, Inc., Louisville Behandlung von mukositis
JP4903558B2 (ja) * 2003-02-14 2012-03-28 ヘンリー エム．ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディシン，インコーポレイティド ガンマ−トコトリエノールによる放射線防護
JP4898447B2 (ja) * 2003-10-14 2012-03-14 プルーロームド インコーポレイテッド 結石破砕術の際の腎結石破片の閉じ込め
EP1906991A2 (en) * 2004-06-28 2008-04-09 Novo Nordisk A/S Use of glp-1 receptor agonists and/or dpp-iv inhibitors in combination with proton pump inhibitors and ppar agonists for the preparation of a medicament for the treatment of diabetes type i, diabetes type ii and impaired pancreatic beta-cell function
CA2635603C (en) * 2005-11-30 2016-01-19 Endo Pharmaceuticals Inc. Treatment of xerostomia
CN100444847C (zh) * 2006-01-11 2008-12-24 刘展欣 一种微粒化地奥司明和橙皮甙组合物栓剂
CA2658337C (en) 2006-06-20 2015-01-20 Izun Pharmaceuticals Corporation Anti-inflammatory dissolvable film
AU2007275217B2 (en) * 2006-07-20 2013-02-07 Izun Pharmaceuticals Corporation Film-delivering rinse
KR101017650B1 (ko) * 2008-03-04 2011-02-25 한국원자력연구원 헤스페리딘 또는 이의 약학적으로 허용가능한 염을유효성분으로 함유하는 세포 보호용 조성물
JP5376889B2 (ja) * 2008-09-30 2013-12-25 小林製薬株式会社 カンジダ症予防又は治療剤
US9597278B2 (en) 2008-11-13 2017-03-21 David A. Hamlin Compositions and methods for alleviating hyposalivation and for providing oral comfort
US9884082B2 (en) 2008-11-13 2018-02-06 David A. Hamlin Compositions and methods for alleviating hyposalivation and for providing oral comfort
FR2940761B1 (fr) * 2009-01-07 2012-12-28 Polymerexpert Sa Composition anti-ronflement contenant un polymere thermogelifiant
ES2683864T3 (es) * 2009-10-01 2018-09-28 Adare Pharmaceuticals, Inc. Composiciones de corticosteroides administradas oralmente
EP2572713B1 (en) * 2011-09-22 2014-08-13 King Saud University Extracts and isolated flavonoids from Euphorbia cuneata useful as anti-ulcer agents
FR2999934B1 (fr) * 2012-12-21 2015-02-20 Servier Lab Composition pharmaceutique sous la forme d'une suspension orale comprenant une fraction flavonoique et de la gomme xanthane
CN103405482B (zh) * 2013-01-25 2016-01-06 丽水同舟药食资源科技开发有限公司 柳叶腊梅提取物在制备治疗炎性肠病和减轻化疗药物引起的消化道损伤的药物中的应用
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
FR3023167B1 (fr) * 2014-07-07 2018-01-12 Laboratoires Rivadis Sas Composition cosmetique ou pharmaceutique a application topique comprenant une association de pectine et d'un extrait de centella asiatica et applications
CN107510690B (zh) * 2016-06-15 2021-03-19 南京简庄生物技术有限公司 一种外用皮肤组织保护及修复制剂
TWI728172B (zh) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748022A (en) * 1985-03-25 1988-05-31 Busciglio John A Topical composition
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
JPH0758963B2 (ja) 1989-01-27 1995-06-21 日本電気株式会社 セル交換装置
CA2011423A1 (en) * 1989-03-07 1990-09-07 Peter M. Taylor Pharmaceutical compositions useful as drug delivery vehicles and/or as wound dressings
IT1250691B (it) * 1991-07-22 1995-04-21 Giancarlo Santus Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
EP0648113A4 (en) * 1992-04-23 1996-12-04 Berlex Lab BIOADHAESIVE FIXED MINERAL OIL EMULSION.
US5281196A (en) * 1992-05-22 1994-01-25 Sultenfuss Thomas J Skin treatment composition and method of use
DE59309337D1 (de) * 1992-07-03 1999-03-11 Alfatec Pharma Gmbh Feste und flüssige Lösungen von Flavonoiden
FR2695034B1 (fr) * 1992-09-01 1994-10-07 Oreal Composition cosmétique ou pharmaceutique comprenant en association une peroxydase et un agent anti-oxygène singulet.
GB9321341D0 (en) * 1993-10-15 1993-12-08 Bristol Myers Squibb Co Therapeutic compositions for use in the treatment of skin lesions and method of making same
DE4444238A1 (de) * 1994-12-13 1996-06-20 Beiersdorf Ag Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden
IN186803B (es) * 1997-02-05 2001-11-10 Panacea Biotec Ltd

Also Published As

Publication number Publication date
ATE235226T1 (de) 2003-04-15
CA2337152C (en) 2008-09-16
CN1310610A (zh) 2001-08-29
FR2781156B1 (fr) 2001-06-29
PT1098631E (pt) 2003-06-30
JP2002521321A (ja) 2002-07-16
DE69906302D1 (de) 2003-04-30
AU4629699A (en) 2000-02-14
EP1098631A1 (fr) 2001-05-16
DK1098631T3 (da) 2003-07-21
WO2000004878A1 (fr) 2000-02-03
EP1098631B1 (fr) 2003-03-26
DE69906302T2 (de) 2003-11-27
US7033606B1 (en) 2006-04-25
CN1149977C (zh) 2004-05-19
CA2337152A1 (en) 2000-02-03
FR2781156A1 (fr) 2000-01-21

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