ES2191095T3 - Acidos tetronicos sustituidos utiles contra el vih y otros retrovirus. - Google Patents

Acidos tetronicos sustituidos utiles contra el vih y otros retrovirus.

Info

Publication number
ES2191095T3
ES2191095T3 ES96911227T ES96911227T ES2191095T3 ES 2191095 T3 ES2191095 T3 ES 2191095T3 ES 96911227 T ES96911227 T ES 96911227T ES 96911227 T ES96911227 T ES 96911227T ES 2191095 T3 ES2191095 T3 ES 2191095T3
Authority
ES
Spain
Prior art keywords
retrovirus
pct
against hiv
tetronic acids
acids against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96911227T
Other languages
English (en)
Inventor
Robert A Chrusciel
Linda Louise Maggiora
Suvit Thaisrivongs
James Michael Tustin
Clark William Smith
Ruben Tommasi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of ES2191095T3 publication Critical patent/ES2191095T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA APLICACION DESCUBRE NUEVOS ACIDOS TETRONICOS PARA EL TRATAMIENTO DEL SIDA Y OTRAS ENFERMEDADES CAUSADAS POR RETROVIRUS.
ES96911227T 1995-03-20 1996-03-07 Acidos tetronicos sustituidos utiles contra el vih y otros retrovirus. Expired - Lifetime ES2191095T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40732295A 1995-03-20 1995-03-20

Publications (1)

Publication Number Publication Date
ES2191095T3 true ES2191095T3 (es) 2003-09-01

Family

ID=23611540

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96911227T Expired - Lifetime ES2191095T3 (es) 1995-03-20 1996-03-07 Acidos tetronicos sustituidos utiles contra el vih y otros retrovirus.

Country Status (11)

Country Link
US (1) US6060600A (es)
EP (1) EP0817786B1 (es)
JP (1) JPH11503416A (es)
AT (1) ATE232867T1 (es)
AU (1) AU5417696A (es)
DE (1) DE69626276T2 (es)
DK (1) DK0817786T3 (es)
ES (1) ES2191095T3 (es)
PT (1) PT817786E (es)
SI (1) SI0817786T1 (es)
WO (1) WO1996029333A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9603097D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline compounds
JP3726684B2 (ja) * 2001-01-11 2005-12-14 株式会社Ｋｄｄｉ研究所 動画像データ転送における輻輳を回避する通信システム
DE102006039912A1 (de) * 2006-08-25 2008-03-20 Bayer Healthcare Ag Substituierte Spirotetronsäuren und ihre Verwendung
DE102006059319A1 (de) * 2006-12-15 2008-06-19 Bayer Healthcare Ag Substituierte Aminofuranone und ihre Verwendung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA852614B (en) * 1985-05-17 1986-10-09 Takeda Chemical Industries, Ltd. Ascorbic acid ethers and their production
JP2515556B2 (ja) * 1986-08-29 1996-07-10 武田薬品工業株式会社 ヒドロキシブテノライド誘導体およびその製造法
KR970005488B1 (ko) * 1988-10-20 1997-04-16 시오노 기세이야꾸 가부시끼가이샤 항생제 pb-6042류
JP3156006B2 (ja) * 1990-07-30 2001-04-16 武田薬品工業株式会社 テトロン酸誘導体、その製造法及び用途
EP0480624A1 (en) * 1990-10-11 1992-04-15 Merck & Co. Inc. Inhibitors of HIV protease
WO1993004055A2 (en) * 1991-08-27 1993-03-04 The Upjohn Company Compounds used for the inhibition of hiv-protease
DE69226487T2 (de) * 1991-09-26 1999-02-18 Nippon Zoki Pharmaceutical Co Verwendung von Furanonderivaten zur Vorbeugung oder Behandlung von Autoimmunkrankheiten
ZA938019B (en) * 1992-11-13 1995-04-28 Upjohn Co Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses
IL108459A0 (en) * 1993-02-05 1994-04-12 Opjohn Company 4-Hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl [B] pyran-2-ones useful for treating infections due to hiv and other retroviruses
CA2168757A1 (en) * 1993-09-17 1995-03-23 Robert A. Chrusciel Substituted tetronic acids useful for treating hiv and other retroviruses

Also Published As

Publication number Publication date
ATE232867T1 (de) 2003-03-15
EP0817786B1 (en) 2003-02-19
JPH11503416A (ja) 1999-03-26
US6060600A (en) 2000-05-09
SI0817786T1 (en) 2003-08-31
DK0817786T3 (da) 2003-05-26
PT817786E (pt) 2003-06-30
AU5417696A (en) 1996-10-08
WO1996029333A1 (en) 1996-09-26
EP0817786A1 (en) 1998-01-14
DE69626276D1 (de) 2003-03-27
DE69626276T2 (de) 2003-11-13

Similar Documents

Publication Publication Date Title
ES2136723T3 (es) Utilizacion de n-aril-metilen-etilen-diamino-triacetatos, n-aril-metilen-imino-diacetatos o n,n'-diaril-metilen-etilen-diamino-acetatos contra el estres oxidante.
MX9205244A (es) Micelas modificadas de caseina.
EE03969B1 (et) (Metüülsulfonüül)fenüül-2-(5H)-furanoonid, nende kasutamine ja farmatseutilised kompositsioonid
ATE204164T1 (de) Pflaster zur behandlung von nagelmykosen
ATE200669T1 (de) 4-hydroxy-benzopyran-2-one und 4-hydroxy- zykloalkyl(b) - pyran--2-one verwendbarfuer die behandlung von retroviralen infectionen
MX9700237A (es) Combinaciones inhibidoras de proteasa retroviral.
KR960701051A (ko) 이미다조피리딘 및 이를 위장 질환의 치료에 사용하는 방법(imidazopyridines and their use in treating castrointestinal diseases)
ES2119185T3 (es) Tratamiento de enfermedades micobacterianas por administracion de productos de la proteina bactericida/que aumenta la permeabilidad.
NO976048L (no) Farmasöytiske og diett formuleringer for profylakse og behandling av mave- og tarmforstyrrelser
BR9812837A (pt) Processo para fazer um composto, e, composto
DE69427344T2 (de) Verabreichung von riluzol zur behandlung von neuro-aids
FI964332A (fi) Eräiden metaanibisfosfonihappojohdannaisten käyttö proteesin löystymisen ja proteesin vaelluksen estämiseen
ATE78031T1 (de) Prostaglandin-derivate zur behandlung von glaucoma oder augenueberdruck.
BR9509975A (pt) Formulação farmacêutica
ATE207295T1 (de) Fungizide mischungen
ES2132383T3 (es) Inhibidores de proteasa hiv.
ES2191095T3 (es) Acidos tetronicos sustituidos utiles contra el vih y otros retrovirus.
ES2180750T3 (es) Conjugado de un principio activo, un polieter y, en caso dado, una proteina nativa no considerada como exogena.
DE69623325D1 (de) 4-hydroxycoumarin-3-carboxamide für die behandlung von nicht-insulin-abhängigen diabetes mellitus
SE9402241L (sv) Inhibitor
ES2049711T3 (es) Uso de bucilamina para la fabricacion de un medicamento para el tratamiento de cistinuria.
MX9201288A (es) Metodo de tratamiento.
OA08973A (fr) Butyl hydroxyanisoles pour le traitement des maladies à rétro-virus
OA09519A (fr) D-acide aspartique b-hydroxamate en tant que medicament
ES2093515T3 (es) Aplicacion del riluzol como radio-restaurador.