ES2189130T3 - Catalizador que contiene una sal de amido-fosfonio para reacciones halex. - Google Patents

Catalizador que contiene una sal de amido-fosfonio para reacciones halex.

Info

Publication number
ES2189130T3
ES2189130T3 ES98903021T ES98903021T ES2189130T3 ES 2189130 T3 ES2189130 T3 ES 2189130T3 ES 98903021 T ES98903021 T ES 98903021T ES 98903021 T ES98903021 T ES 98903021T ES 2189130 T3 ES2189130 T3 ES 2189130T3
Authority
ES
Spain
Prior art keywords
carbon atoms
salt
rent
equal
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98903021T
Other languages
English (en)
Inventor
Sergej Pasenok
Wolfgang Appel
Ralf Pfirmann
Thomas Wessel
Thomas Schach
Hans Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clariant Produkte Deutschland GmbH
Original Assignee
Clariant GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant GmbH filed Critical Clariant GmbH
Application granted granted Critical
Publication of ES2189130T3 publication Critical patent/ES2189130T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0201—Oxygen-containing compounds
    • B01J31/0202—Alcohols or phenols
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0201—Oxygen-containing compounds
    • B01J31/0204—Ethers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0235—Nitrogen containing compounds
    • B01J31/0239—Quaternary ammonium compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0255—Phosphorus containing compounds
    • B01J31/0267—Phosphines or phosphonium compounds, i.e. phosphorus bonded to at least one carbon atom, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, the other atoms bonded to phosphorus being either carbon or hydrogen
    • B01J31/0268—Phosphonium compounds, i.e. phosphine with an additional hydrogen or carbon atom bonded to phosphorous so as to result in a formal positive charge on phosphorous
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B39/00—Halogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
    • C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
    • C07C17/208—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being MX
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

SE EXPONE UN CATALIZADOR PARA REACCIONES DE INTERCAMBIO HALOGENOS - FLUOR DE COMPUESTOS AROMATICOS, QUE CONSISTE BASICAMENTE EN UNA MEZCLA DE UNO O MAS COMPUESTOS (A) Y AL MENOS UN COMPUESTO (B), (C) Y/O (D). (A) ES UNA SAL DE AMIDOFOSFONIO DE FORMULA (I); EN LA QUE A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 Y A 8 SON IGUALES O DIFERENTES Y REPRESENTAN INDEPENDIENTEMENTE UN ALQUILO O ALQUENILO, DE CADERA RECTA O RAMIFICADA, CON 1 A 12 ATOMOS DE CARBONO, CICLOALQUILO CON 4 A 8 ATOMOS DE CARBONO, ARILO CON 6 A 12 ATOMOS DE CARBONO, ARALQUILO CON 7 A 12 ATOMOS DE CARBONO, O A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 Y A8 SON INDEPENDIENTES, IGUALES O DIFERENTES Y SE UNEN ENT RE SI DIRECTAMENTE O A TRAVES DE O O N - A 9 EN UN ANILLO CON 3 A 7 MIEMBROS; A 9 REPRESENTA UN ALQUILO CON 1 A 4 ATOMOS DE CARBONO, Y B - REPRESENTA UN RADICAL ACIDO MONOV ALENTE O EL EQUIVALENTE DE UN RADICAL ACIDO POLIVALENTE; (B) ES UNA SAL DE AMONIO CUATERNARIO; (C) ES UNA SAL DE FOSFONIO CUATERNARIO; (D) ES UN ETER DE CORONA O POLIETER DE FORMULA (IV) R 10 - (O - C X H 2X ) R - OR 11 , EN DONDE R 10 Y R 11 SON IGUALES O DIFERENTES Y REPRESEN TAN UN RADICAL ALQUILO, LINEAL O RAMIFICADO, CON 1 A 16, Y PREFERENTEMENTE 1 A 8, ATOMOS DE CARBONO; X ES UN NUMERO ENTERO DE 2 A 6, PREFERENTEMENTE DE 2 A 3; Y R ES UN NUMERO ENTERO DE 0 A 20, PREFERENTEMENTE DE 1 A 18, Y EN PARTICULAR DE 4 A 14.
ES98903021T 1997-01-23 1998-01-22 Catalizador que contiene una sal de amido-fosfonio para reacciones halex. Expired - Lifetime ES2189130T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702282A DE19702282C2 (de) 1997-01-23 1997-01-23 Katalysator für Halex-Reaktionen

Publications (1)

Publication Number Publication Date
ES2189130T3 true ES2189130T3 (es) 2003-07-01

Family

ID=7818130

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98903021T Expired - Lifetime ES2189130T3 (es) 1997-01-23 1998-01-22 Catalizador que contiene una sal de amido-fosfonio para reacciones halex.

Country Status (11)

Country Link
US (1) US6103659A (es)
EP (1) EP0958052B1 (es)
JP (1) JP2001508359A (es)
KR (1) KR20000070390A (es)
CN (1) CN1244139A (es)
CA (1) CA2278533A1 (es)
DE (2) DE19702282C2 (es)
ES (1) ES2189130T3 (es)
RU (1) RU2198732C2 (es)
WO (1) WO1998032532A1 (es)
ZA (1) ZA98517B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69711220T2 (de) 1996-11-22 2002-10-31 Albemarle Corp Halogenaustausch-reaktionen und ihre anwendungen
US6215032B1 (en) * 1998-02-10 2001-04-10 Albemarle Corporation Catalyst recovery for halogen exchange reactions
DE19836698A1 (de) * 1998-08-13 2000-02-17 Bayer Ag Verfahren zur Herstellung von fluorierten Benzylalkoholen und -aldehyden
DE19934595A1 (de) 1999-07-23 2001-01-25 Clariant Gmbh Neue Aminophosphoniumverbindungen
DE19934594A1 (de) * 1999-07-23 2001-01-25 Clariant Gmbh Tetrakis(pyrrolidino/piperidino) phosphoniumsalze enthaltende Mischungen
FR2823451B1 (fr) * 2001-04-12 2004-01-30 Rhodia Chimie Sa Catalyseurs de substitution aromatique nucleophile, composition en contenant et utilisation pour une substitution sn ar
EP1377376A1 (fr) * 2001-04-12 2004-01-07 Rhodia Chimie Catalyseurs pour substitution nucleophile, leur synthese, composition en contenant et leur utilisation
DE10129057A1 (de) * 2001-06-15 2002-12-19 Bayer Ag Verbessertes Verfahren zur Herstellung kernfluorierter Aromaten
DE10307558A1 (de) * 2003-02-21 2004-09-02 Clariant Gmbh Phosphazeniumsalz-Mischungen enthaltend Hexakis(amino)diphosphazenium Tetrakis(amino)-phosphonium und Polyaminophosphazenium-Salze
DE102004033525A1 (de) * 2004-07-08 2006-02-02 Lanxess Deutschland Gmbh Verbessertes Verfahren zur Herstellung kernfluorierter Aromaten
DE102005044451A1 (de) 2005-09-17 2007-03-22 Bayer Cropscience Gmbh Verfahren zum Herstellen von 5-Fluor-1,3-dialkyl-1H-pyrazol-4-carbonsäurefluoriden
RU2409584C2 (ru) * 2005-12-02 2011-01-20 Канто Денка Когио Ко., Лтд. Ионная жидкость, содержащая катион фосфония со связью p-n, и способ ее получения
ES2431592T3 (es) * 2006-07-18 2013-11-27 The Board Of Regents Of The University Of Nebraska Métodos y agentes para preparar agentes de fluoración radiomarcados con 18F
DE102008051412A1 (de) 2008-10-11 2010-04-15 Saltigo Gmbh Katalysatoren zur Herstellung von Fluoraromaten
JP5411494B2 (ja) * 2008-12-26 2014-02-12 ユアン シン マテリアルズ テクノロジー コーポレイション １，４−ビス（ジフルオロメチル）テトラフルオロベンゼンの製造方法
CN103467436B (zh) * 2013-08-29 2015-07-08 中国海洋石油总公司 一种氟代碳酸乙烯酯的制备方法
EA031804B1 (ru) 2014-02-03 2019-02-28 Вайтаи Фармасьютиклз, Инк. Дигидропирролопиридиновые ингибиторы ror-гамма
HUE042335T2 (hu) 2014-10-14 2019-06-28 Vitae Pharmaceuticals Inc ROR-gamma dihidropirrolopiridin inhibitorai
US9845308B2 (en) 2014-11-05 2017-12-19 Vitae Pharmaceuticals, Inc. Isoindoline inhibitors of ROR-gamma
US9663515B2 (en) 2014-11-05 2017-05-30 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
EP3331876B1 (en) 2015-08-05 2020-10-07 Vitae Pharmaceuticals, LLC Modulators of ror-gamma
CN105315142A (zh) * 2015-11-20 2016-02-10 扬州天辰精细化工有限公司 2,6-二氟苯甲醛的工业化生产方法
EP3377482B1 (en) 2015-11-20 2021-05-12 Vitae Pharmaceuticals, LLC Modulators of ror-gamma
TW202220968A (zh) 2016-01-29 2022-06-01 美商維它藥物有限責任公司 ＲＯＲ－γ調節劑
US9481674B1 (en) 2016-06-10 2016-11-01 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
CN107141192B (zh) * 2017-05-09 2019-10-11 大连奇凯医药科技有限公司 一种均三氟苯的制备方法
WO2019018975A1 (en) 2017-07-24 2019-01-31 Vitae Pharmaceuticals, Inc. INHIBITORS OF ROR GAMMA
CN115650976A (zh) 2017-07-24 2023-01-31 生命医药有限责任公司 RORγ的抑制剂
CN108069994B (zh) * 2017-12-20 2019-05-14 江苏中旗科技股份有限公司 一类含硼化合物及其在催化氟化反应中的应用
CN108586257B (zh) * 2018-05-03 2020-12-22 浙江解氏新材料股份有限公司 一种对氟硝基苯的制备方法
TWI712586B (zh) * 2018-07-20 2020-12-11 泰商Ｓｃｇ化學股份有限公司 用於將乙苯自其他ｃ芳族化合物中分離出之製程

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2083631T3 (es) * 1991-07-17 1996-04-16 Hoechst Ag Procedimiento para la preparacion de clorofluoronitrobencenos.
DE4324366C1 (de) * 1993-07-21 1994-09-22 Hoechst Ag Katalysator für nukleophile aromatische Substitutionen
US5502235A (en) * 1994-12-28 1996-03-26 Dowelanco Solventless process for making 2,6 difluorobenzonitrile
DE19631854C1 (de) * 1996-08-07 1998-04-30 Hoechst Ag Verfahren zur Herstellung von Fluor enthaltenden Verbindungen

Also Published As

Publication number Publication date
WO1998032532A1 (de) 1998-07-30
EP0958052A1 (de) 1999-11-24
ZA98517B (en) 1999-03-04
CN1244139A (zh) 2000-02-09
DE19702282A1 (de) 1998-07-30
EP0958052B1 (de) 2002-12-04
RU2198732C2 (ru) 2003-02-20
KR20000070390A (ko) 2000-11-25
DE59806529D1 (de) 2003-01-16
CA2278533A1 (en) 1998-07-30
DE19702282C2 (de) 1998-11-19
US6103659A (en) 2000-08-15
JP2001508359A (ja) 2001-06-26

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