ES2186926T3 - Deteccion de la predisposicion genetica a la retinopatia diabetica amenazante de la vision. - Google Patents

Deteccion de la predisposicion genetica a la retinopatia diabetica amenazante de la vision.

Info

Publication number
ES2186926T3
ES2186926T3 ES97944986T ES97944986T ES2186926T3 ES 2186926 T3 ES2186926 T3 ES 2186926T3 ES 97944986 T ES97944986 T ES 97944986T ES 97944986 T ES97944986 T ES 97944986T ES 2186926 T3 ES2186926 T3 ES 2186926T3
Authority
ES
Spain
Prior art keywords
diabetic retinopathy
vision
detection
genetic predisposition
identified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97944986T
Other languages
English (en)
Inventor
Gordon Duff
Ian Rennie
Robert Richardson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Interleukin Genetics Inc
Original Assignee
Interleukin Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interleukin Genetics Inc filed Critical Interleukin Genetics Inc
Application granted granted Critical
Publication of ES2186926T3 publication Critical patent/ES2186926T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Catching Or Destruction (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

ESTA INVENCION SE REFIERE A UN PROCEDIMIENTO Y A UNA INSTRUMENTACION PARA PREDECIR UN RIESGO INCREMENTADO DE RETINOPATIA DIABETICA CON RIESGO DE AMENAZA DE LA VISION, QUE INCLUYE EL AISLAMIENTO DEL ADN GENOMICO A PARTIR DE UNA MUESTRA TOMADA EN UN PACIENTE DIABETICO. EL MOTIVO DE POLIMORFISMO GENETICO PARA LOS GENES IL -1A, IL - 1B Y IL 1RN SE IDENTIFICA LUEGO EN EL ADN. EL MOTIVO IDENTIFICADO SE COMPARA CON MOTIVOS TESTIGOS DE POLIMORFISMOS CONOCIDOS Y SE IDENTIFICAN LOS PACIENTES QUE EXPRESAN UN MOTIVO DE POLIMORFISMO GENETICO ASOCIADO CON UN RIESGO INCREMENTADO DE RETINOPATIA DIABETICA CON RIESGO DE AMENAZA DE LA VISION.
ES97944986T 1996-10-10 1997-10-09 Deteccion de la predisposicion genetica a la retinopatia diabetica amenazante de la vision. Expired - Lifetime ES2186926T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9621129.7A GB9621129D0 (en) 1996-10-10 1996-10-10 Detecting genetic predisposition to sight-threatening diabetic retinopathy

Publications (1)

Publication Number Publication Date
ES2186926T3 true ES2186926T3 (es) 2003-05-16

Family

ID=10801212

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97944986T Expired - Lifetime ES2186926T3 (es) 1996-10-10 1997-10-09 Deteccion de la predisposicion genetica a la retinopatia diabetica amenazante de la vision.

Country Status (12)

Country Link
US (1) US6713253B1 (es)
EP (1) EP0950113B1 (es)
AT (1) ATE224456T1 (es)
AU (1) AU742957B2 (es)
CA (1) CA2267155C (es)
DE (1) DE69715669T2 (es)
DK (1) DK0950113T3 (es)
ES (1) ES2186926T3 (es)
GB (1) GB9621129D0 (es)
IL (1) IL129390A (es)
WO (1) WO1998015653A1 (es)
ZA (1) ZA979071B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009040461A2 (es) * 2007-09-26 2009-04-02 Universidade De Santiago De Compostela Método para la detección del riesgo de desarrollar vitreorretinopatía proliferante (vrp).

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524795B1 (en) 1997-03-10 2003-02-25 Interleukin Genetics, Inc. Diagnostics for cardiovascular disorders
US6720141B1 (en) * 1999-11-01 2004-04-13 Interleukin Genetics, Inc. Diagnostics and therapeutics for restenosis
GB9711040D0 (en) 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
US20050032077A1 (en) * 1998-03-10 2005-02-10 Duff Gordon W. Detecting genetic predisposition to sight-threatening diabetic retinopathy
US6733967B1 (en) 1998-04-21 2004-05-11 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
IL139131A0 (en) * 1998-04-21 2001-11-25 Interleukin Genetics Inc Fetal testing for prediction of low birth weight
US6251598B1 (en) * 1998-10-30 2001-06-26 Interleukin Genetics, Inc. Methods for diagnosing sepsis
US20090023147A1 (en) * 1999-08-30 2009-01-22 Kenneth Kornman Diagnostics and therapeutics for osteoporosis
WO2001056606A1 (fr) * 2000-01-31 2001-08-09 Santen Pharmaceutical Co., Ltd. Remedes pour troubles ophtalmiques
GB0009294D0 (en) * 2000-04-15 2000-05-31 Sec Dep For The Home Departmen Improvements in and relating to analysis of DNA samples
AU2002359431A1 (en) * 2001-11-19 2003-06-10 Interleukin Genetics, Inc. Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
JP2005529585A (ja) * 2002-01-25 2005-10-06 インターリューキン ジェネティックス インコーポレイテッド Il−1遺伝子群ならびに関連する炎症性多型およびハプロタイプ
AU2003271725A1 (en) * 2002-10-15 2004-05-04 Novartis Ag Methods to predict edema as a side effect of drug treatment
JP2007501627A (ja) * 2003-08-08 2007-02-01 インタールーキン ジェネティックス インク 骨粗鬆症のための診断法および治療法
GB0417763D0 (en) * 2004-07-09 2004-09-08 Sec Dep For The Home Departmen Improvements in and relating to the investigation of dna samples
WO2007050794A2 (en) 2005-10-25 2007-05-03 Interleuken Genetics, Inc. The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes
US20090053816A1 (en) * 2006-03-24 2009-02-26 University Of Louisville Research Foundation, Inc. Hemoglobin-based methods for prophylaxis, diagnosis and/or treatment of retinal disorders
WO2007113490A1 (en) * 2006-04-03 2007-10-11 Forensic Science Service Limited Improvements in and relating to analysis of mixed source dna profiles
US20110092446A1 (en) * 2007-07-20 2011-04-21 Cedric Francois Compositions and methods for treatment of trauma
CA2705142A1 (en) * 2007-11-08 2009-05-14 Interleukin Genetics, Inc. Diagnostics for aging-related dermatologic disorders
US20100098775A1 (en) * 2008-05-02 2010-04-22 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
EP2304052A2 (en) * 2008-05-02 2011-04-06 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
EP3402900A1 (en) 2016-01-12 2018-11-21 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
WO2020245402A1 (en) 2019-06-06 2020-12-10 Cardioforecast Ltd Compositions and methods for treating lung, colorectal and breast cancer
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007464A1 (en) 1985-06-14 1986-12-18 Genetic Systems Corporation Methods for identifying alleles associated with increased risk of diabetes
US5039606A (en) 1987-10-29 1991-08-13 Virginia Mason Research Center Diagnostic probe for diabetes type I predisposition
US5686246A (en) 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
US5698399A (en) 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009040461A2 (es) * 2007-09-26 2009-04-02 Universidade De Santiago De Compostela Método para la detección del riesgo de desarrollar vitreorretinopatía proliferante (vrp).
WO2009040461A3 (es) * 2007-09-26 2009-06-11 Univ Santiago Compostela Método para la detección del riesgo de desarrollar vitreorretinopatía proliferante (vrp).
ES2337115A1 (es) * 2007-09-26 2010-04-20 Universidade De Santiago De Compostela Metodo para la deteccion del riesgo de desarrollar vitreorretinopatia proliferante (vrp).
ES2337115B2 (es) * 2007-09-26 2011-01-24 Universidade De Santiago De Compostela Metodo para la deteccion del riesgo de desarrollar vitreorretinopatiaproliferante (vrp).

Also Published As

Publication number Publication date
IL129390A (en) 2002-05-23
WO1998015653A1 (en) 1998-04-16
DE69715669D1 (de) 2002-10-24
DE69715669T2 (de) 2003-09-18
ATE224456T1 (de) 2002-10-15
AU4631197A (en) 1998-05-05
CA2267155A1 (en) 1998-04-16
DK0950113T3 (da) 2003-01-27
GB9621129D0 (en) 1996-11-27
ZA979071B (en) 1998-07-08
EP0950113A1 (en) 1999-10-20
CA2267155C (en) 2003-07-08
IL129390A0 (en) 2000-02-17
AU742957B2 (en) 2002-01-17
EP0950113B1 (en) 2002-09-18
US6713253B1 (en) 2004-03-30

Similar Documents

Publication Publication Date Title
ES2186926T3 (es) Deteccion de la predisposicion genetica a la retinopatia diabetica amenazante de la vision.
MX9800941A (es) Deteccion de la predisposicion genetica a la enfermedad periodontal.
CA2282746A1 (en) Prediction of coronary artery disease
WO1998028444A3 (en) Customized oligonucleotide microchips as multiple biosensors
DE69833758D1 (de) Verfahren zur erkennung von genpolymorphismen und allelexpression unter verwendung von sondenchips
Schneider Basic issues in forensic DNA typing
ATE331039T1 (de) Feststellung von endometriumkrebs
WO2003089897A3 (en) Diagnosis and treatment of vascular disease
DE69739183D1 (de) Bestimmung des kollagen genotyps
EP0398709A3 (en) Genetic diagnosis of torsion dystonia
DE69710469D1 (de) Diagnoseverfahren und vorrichtung zum nachweis der prädisposition zu bestimmten krankheitszuständen, insbesondere osteoporose, auf basis von il-6 genpolymorphismus
WO2001004349A3 (en) Method for the diagnosis or the prognosis of alzheimer disease therapeutical composition for preventing or treating alzheimer disease
WO2007053732A3 (en) Promoter polymorphisms of the blys gene and use in diagnostic methods
Xu et al. Two multiplex PCR-based DNA assays for the thrombosis risk factors prothrombin G20210A and coagulation factor V G1691A polymorphisms
WO2003014879A3 (en) System and method for identifying a genetic risk factor for a disease or pathology
DE60230988D1 (de) Proteine in der diabetes-proteomanalyse
WO2002053018A3 (en) Method of detecting polymorphisms associated with breast carcinoma in mhc genes
Chessa et al. Simultaneous identification of CSN1S2 A, B, C, and E alleles in goats by polymerase chain reaction-single strand conformation polymorphism
WO2001077380A3 (en) Method for predicting predisposition to a disease associated with mutations in a rpgr gene
Giannattasio et al. Detection of microsatellites by ethidium bromide staining. The analysis of an STR system in the human phenylalanine hydroxylase gene
Johnson et al. Segregation of linked probes to myotonic dystrophy in a family demonstrating that 152 and APOC2 are on the same side of DM on 19q
CA2263712A1 (en) Methods for diagnosing and assessing a predisposition to bipolar affective disorder
RU98111689A (ru) Способ диагностики заболеваний, связанных со спазмом коронарной артерии
WO2002090585A3 (en) Genetic polymorphism pattern of tgfb1 as marker for susceptability to renal disease
WO1999035286A3 (en) Assay for predicting the angiographic response to lipid-lowering therapy in patients