ES2182962T3 - Productos farmaceuticos y ensayos que usan subunidades enzimaticas. - Google Patents
Productos farmaceuticos y ensayos que usan subunidades enzimaticas.Info
- Publication number
- ES2182962T3 ES2182962T3 ES96903111T ES96903111T ES2182962T3 ES 2182962 T3 ES2182962 T3 ES 2182962T3 ES 96903111 T ES96903111 T ES 96903111T ES 96903111 T ES96903111 T ES 96903111T ES 2182962 T3 ES2182962 T3 ES 2182962T3
- Authority
- ES
- Spain
- Prior art keywords
- agent
- subunities
- tests
- pharmaceutical products
- constituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
- A61K47/6899—Antibody-Directed Enzyme Prodrug Therapy [ADEPT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Nanotechnology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Medical Informatics (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
UN METODO PARA LIBERAR UN AGENTE (POR EJEMPLO UN QUIMIOTERAPICO) EN CONDICIONES PREDETERMINADAS MEDIANTE LAS FASES DE PROTECCION DE DICHO AGENTE CON UNA ESTRUCTURA LIPIDICA (POR EJEMPLO UN LIPOSOMA), INICIO DE LA ACTIVIDAD DE LIPASA MEDIANTE LA COMBINACION DE DOS O MAS COMPONENTES (POR EJEMPLO FRAGMENTOS DE ALFA UNA MOLECULA DIRECTRIZ (POR EJEMPLO UN ANTICUERPO) QUE SE UNE A UNA DIANA (POR EJEMPLO UN ANTIGENO TUMORAL) EN CONDICIONES PREDETERMINADAS. LA ESTRUCTURA LIPIDICA SE EXPONE SEGUIDAMENTE A LA ACTIVIDAD LIPASA CONSTITUIDA DE MODO QUE SE LIBERA EL AGENTE. SE DESCUBREN ASIMISMO MATERIALES Y KITS PARA UTILIZARLOS EN EL METODO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9503486.4A GB9503486D0 (en) | 1995-02-22 | 1995-02-22 | Pharmaceuticals and assays using enzyme subunits |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2182962T3 true ES2182962T3 (es) | 2003-03-16 |
Family
ID=10770034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96903111T Expired - Lifetime ES2182962T3 (es) | 1995-02-22 | 1996-02-21 | Productos farmaceuticos y ensayos que usan subunidades enzimaticas. |
Country Status (15)
Country | Link |
---|---|
US (2) | US6472365B1 (es) |
EP (1) | EP0810880B1 (es) |
JP (1) | JPH11500136A (es) |
KR (1) | KR19980702499A (es) |
CN (1) | CN1188704C (es) |
AT (1) | ATE224204T1 (es) |
AU (1) | AU714396B2 (es) |
CA (1) | CA2213566A1 (es) |
DE (1) | DE69623755T2 (es) |
DK (1) | DK0810880T3 (es) |
ES (1) | ES2182962T3 (es) |
GB (1) | GB9503486D0 (es) |
PT (1) | PT810880E (es) |
WO (1) | WO1996025952A1 (es) |
ZA (1) | ZA961427B (es) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4463090A (en) * | 1981-09-30 | 1984-07-31 | Harris Curtis C | Cascade amplification enzyme immunoassay |
US4900556A (en) | 1985-04-26 | 1990-02-13 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
GB8528761D0 (en) | 1985-11-22 | 1985-12-24 | Axon Healthcare Ltd | Enzyme-coupled antibodies |
US4874710A (en) * | 1986-02-20 | 1989-10-17 | Becton Dickinson And Company | Assay and product in which binder and liposomes are supported on a solid support |
EP0301333A3 (en) * | 1987-07-29 | 1992-07-01 | Abbott Laboratories | Liposome based homogeneous immunoassay for diagnostic tests |
US5356633A (en) * | 1989-10-20 | 1994-10-18 | Liposome Technology, Inc. | Method of treatment of inflamed tissues |
JPH04200632A (ja) * | 1990-11-29 | 1992-07-21 | Toyo Ink Mfg Co Ltd | リポソームの破壊方法 |
JPH0556797A (ja) | 1991-08-31 | 1993-03-09 | Toyo Ink Mfg Co Ltd | リポソーム破壊物質の検出方法 |
US5277913A (en) * | 1991-09-09 | 1994-01-11 | Thompson David H | Liposomal delivery system with photoactivatable triggered release |
DE69407292T2 (de) * | 1993-06-30 | 1998-06-25 | Genentech Inc | Verfahren zur herstellung von liposomen |
-
1995
- 1995-02-22 GB GBGB9503486.4A patent/GB9503486D0/en active Pending
-
1996
- 1996-02-21 AU AU47259/96A patent/AU714396B2/en not_active Ceased
- 1996-02-21 DE DE69623755T patent/DE69623755T2/de not_active Expired - Fee Related
- 1996-02-21 PT PT96903111T patent/PT810880E/pt unknown
- 1996-02-21 US US08/894,527 patent/US6472365B1/en not_active Expired - Fee Related
- 1996-02-21 CA CA002213566A patent/CA2213566A1/en not_active Abandoned
- 1996-02-21 ES ES96903111T patent/ES2182962T3/es not_active Expired - Lifetime
- 1996-02-21 WO PCT/GB1996/000380 patent/WO1996025952A1/en active IP Right Grant
- 1996-02-21 EP EP96903111A patent/EP0810880B1/en not_active Expired - Lifetime
- 1996-02-21 KR KR1019970705899A patent/KR19980702499A/ko active IP Right Grant
- 1996-02-21 JP JP8525485A patent/JPH11500136A/ja not_active Withdrawn
- 1996-02-21 CN CNB961934344A patent/CN1188704C/zh not_active Expired - Fee Related
- 1996-02-21 AT AT96903111T patent/ATE224204T1/de not_active IP Right Cessation
- 1996-02-21 DK DK96903111T patent/DK0810880T3/da active
- 1996-02-22 ZA ZA961427A patent/ZA961427B/xx unknown
-
2001
- 2001-11-21 US US09/989,130 patent/US6974699B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK0810880T3 (da) | 2003-01-06 |
AU4725996A (en) | 1996-09-11 |
EP0810880A1 (en) | 1997-12-10 |
AU714396B2 (en) | 2000-01-06 |
KR19980702499A (ko) | 1998-07-15 |
CN1188704C (zh) | 2005-02-09 |
CA2213566A1 (en) | 1996-08-29 |
JPH11500136A (ja) | 1999-01-06 |
WO1996025952A1 (en) | 1996-08-29 |
PT810880E (pt) | 2003-02-28 |
DE69623755D1 (de) | 2002-10-24 |
ZA961427B (en) | 1996-08-07 |
US6974699B2 (en) | 2005-12-13 |
EP0810880B1 (en) | 2002-09-18 |
GB9503486D0 (en) | 1995-04-12 |
US20020035084A1 (en) | 2002-03-21 |
ATE224204T1 (de) | 2002-10-15 |
DE69623755T2 (de) | 2003-06-05 |
US6472365B1 (en) | 2002-10-29 |
CN1182372A (zh) | 1998-05-20 |
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