ES2177654T3 - Remedio contra la degeneracion espinocerebelosa. - Google Patents

Remedio contra la degeneracion espinocerebelosa.

Info

Publication number
ES2177654T3
ES2177654T3 ES95927966T ES95927966T ES2177654T3 ES 2177654 T3 ES2177654 T3 ES 2177654T3 ES 95927966 T ES95927966 T ES 95927966T ES 95927966 T ES95927966 T ES 95927966T ES 2177654 T3 ES2177654 T3 ES 2177654T3
Authority
ES
Spain
Prior art keywords
sup
sub
degeneration
spinocerebelus
represent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95927966T
Other languages
English (en)
Inventor
Tetsuo Sakai
Yasunobu Antoku
Toyojiro Matsuishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ES2177654T3 publication Critical patent/ES2177654T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRESENTA UN MEDICAMENTO PARA LA DEGENERACION ESPINOCEREBELOSA QUE COMPRENDE UN COMPUESTO REPRESENTADO POR LA FORMULA GENERAL (I) O UNA SAL FARMACOLOGICAMENTE ACEPTABLE DEL MISMO, COMO INGREDIENTE ACTIVO EN DONDE R{SUP,1} Y R{SUP,2} REPRESENTAN CADA UNA HIDROGENO O ESTAN COMBINADAS ENTRE SI PARA REPRESENTAR UN ENLACE SIMPLE; Y R{SUP,3} REPRESENTA CH(OH)CH(CH)CH{SUB,3}, CH(OCOCH{SUB,3}) CH(OCOCH{SUB,3}CH{SUB,3}, -CH{SUB,3}, -CH{SUB,2}OH O FENILO CUANDO R{SUP,1} Y R{SUP,2} REPRESENTAN CADA UNA HIDROGENO, MIENTRAS R{SUP,3} REPRESENTA COCH(OH)CH{SUB,3} CUANDO R{SUP,1} Y R{SUP,2} JUNTAS REPRESENTAN UN ENLACE SIMPLE.
ES95927966T 1994-08-05 1995-08-04 Remedio contra la degeneracion espinocerebelosa. Expired - Lifetime ES2177654T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18468294 1994-08-05

Publications (1)

Publication Number Publication Date
ES2177654T3 true ES2177654T3 (es) 2002-12-16

Family

ID=16157531

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95927966T Expired - Lifetime ES2177654T3 (es) 1994-08-05 1995-08-04 Remedio contra la degeneracion espinocerebelosa.

Country Status (6)

Country Link
US (1) US5753656A (es)
EP (1) EP0722731B1 (es)
AT (1) ATE218345T1 (es)
DE (1) DE69526918T2 (es)
ES (1) ES2177654T3 (es)
WO (1) WO1996003989A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4418097A1 (de) 1994-05-24 1995-11-30 Cassella Ag Verwendung von Tetrahydropteridin-Derivaten als Hemmstoffe der NO-Synthase
EP0884317B1 (en) * 1996-07-31 2005-05-18 Cmic Co., Ltd. Active oxygen scavengers containing pterin derivatives
KR20060094988A (ko) 1996-08-30 2006-08-30 다이이치 아스비오파마 가부시키가이샤 질소 산화물 합성효소 (ｎｏｓ)의 기능 저하에 의해유발되는 질환의 예방 또는 치료제
JP4306825B2 (ja) 1998-02-27 2009-08-05 アスビオファーマ株式会社 インスリン抵抗性が関与する血管機能異常を伴う疾患の予防または治療剤
US7610233B1 (en) 1999-12-22 2009-10-27 Accenture, Llp System, method and article of manufacture for initiation of bidding in a virtual trade financial environment
US7167844B1 (en) 1999-12-22 2007-01-23 Accenture Llp Electronic menu document creator in a virtual financial environment
US6623754B2 (en) * 2001-05-21 2003-09-23 Noveon Ip Holdings Corp. Dosage form of N-acetyl cysteine
BR0308556A (pt) * 2002-03-21 2005-05-03 Martin C Hinnz Tecnologia de otimização do segmento de sistema de serotonina e de catecolaminas
US20070293571A1 (en) * 2006-06-08 2007-12-20 Hinz Martin C Adminstration of dopa precursors with sources of dopa to effectuate optimal catecholamine neurotransmitter outcomes
US20090311795A1 (en) * 2002-03-21 2009-12-17 Hinz Martin C Bilateral control of functions traditionally regulated by only serotonin or only dopamine
US20060110325A1 (en) * 2003-02-21 2006-05-25 Hinz Martin C Serotonin and catecholamine segment optimization technology
DE10260263A1 (de) * 2002-12-20 2004-07-15 Biocrates Life Sciences Gmbh Verwendung von Tetrahydrobiopterinderivaten zur Behandlung und Ernährung von Patienten mit Aminosäurestoffwechselstörungen
US7442372B2 (en) 2003-08-29 2008-10-28 Biomarin Pharmaceutical Inc. Delivery of therapeutic compounds to the brain and other tissues
EP1696877A4 (en) * 2003-11-13 2010-06-09 Gen Hospital Corp PROCESS FOR PAIN TREATMENT
CA2545584C (en) * 2003-11-17 2012-10-23 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of metabolic disorders
EP1757293B1 (en) * 2004-05-11 2012-10-10 Daiichi Sankyo Company, Limited Bh4-responsive hyperphenylalaninemia remedies
MX2007005039A (es) * 2004-11-17 2007-06-19 Biomarin Pharm Inc Formulacion de tableta estable.
CA2588994A1 (en) * 2004-12-08 2006-06-15 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of pulmonary hypertension of the newborn
AU2006321942A1 (en) * 2005-12-05 2007-06-14 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of disease
WO2008089148A1 (en) * 2007-01-12 2008-07-24 Biomarin Pharmaceutical Inc. Method of treating a metabolic or neuropsychiatry disorder with a bh4 derivative prodrug
JP2010515747A (ja) * 2007-01-12 2010-05-13 ビオマリン プハルマセウトイカル インコーポレイテッド テトラヒドロビオプテリンプロドラッグ
CN101678025A (zh) 2007-04-11 2010-03-24 生物马林药物股份有限公司 四氢生物蝶呤组合物及其测量方法
BRPI0821970A2 (pt) * 2008-01-03 2015-06-23 Biomarin Pharm Inc Análogos de pterina para tratamento de condição responsiva a bh4
JP5066756B2 (ja) 2010-04-22 2012-11-07 学校法人日本大学 脳機能障害予防・改善用の薬剤及び飲食物
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin
NZ759647A (en) * 2017-06-02 2022-02-25 Fujifilm Toyama Chemical Co Ltd Agent for preventing or treating spinocerebellar ataxia
CN112543758A (zh) * 2018-05-30 2021-03-23 Ptc医疗Mp公司 墨蝶呤的药学上可接受的盐

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5925323A (ja) 1982-03-03 1984-02-09 鐘淵化学工業株式会社 プテリン誘導体からなる脳内神経伝達物質の関わる疾病の治療剤
ZA836957B (en) * 1982-09-20 1985-04-24 Wellcome Found Neurologically active chemical compounds
JPS61277618A (ja) * 1985-06-04 1986-12-08 Suntory Ltd 自閉症治療剤
JP2588191B2 (ja) * 1987-04-24 1997-03-05 サントリー株式会社 悪性腫瘍および重症ウイルス感染症に伴う神経症状を改善するための治療剤
ATE180493T1 (de) * 1991-11-16 1999-06-15 Suntory Ltd Rezeptor für 6(r)-l-erythro-5,6,7,8- tetrahydrobiopterin

Also Published As

Publication number Publication date
ATE218345T1 (de) 2002-06-15
DE69526918T2 (de) 2002-12-19
WO1996003989A1 (fr) 1996-02-15
US5753656A (en) 1998-05-19
EP0722731A4 (en) 1998-03-04
EP0722731B1 (en) 2002-06-05
EP0722731A1 (en) 1996-07-24
DE69526918D1 (de) 2002-07-11

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