ES2173545T3 - Composicion parasiticida inyectable de larga accion y procedimiento para prepararla. - Google Patents

Composicion parasiticida inyectable de larga accion y procedimiento para prepararla.

Info

Publication number
ES2173545T3
ES2173545T3 ES98200868T ES98200868T ES2173545T3 ES 2173545 T3 ES2173545 T3 ES 2173545T3 ES 98200868 T ES98200868 T ES 98200868T ES 98200868 T ES98200868 T ES 98200868T ES 2173545 T3 ES2173545 T3 ES 2173545T3
Authority
ES
Spain
Prior art keywords
prepare
procedure
injectable
final
long action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98200868T
Other languages
English (en)
Inventor
Jorge Carlos Lamberti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogenesis SA
Original Assignee
Biogenesis SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenesis SA filed Critical Biogenesis SA
Application granted granted Critical
Publication of ES2173545T3 publication Critical patent/ES2173545T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBE UNA COMPOSICION PARASITICIDA DE ACCION PROLONGADA INYECTABLE, QUE INCLUYE LA SUFICIENTE IVERMECTINA PARA LOGRAR UNA CONCENTRACION FINAL DE APROXIMADAMENTE UN 1 % (P/P), ALCOHOL BENCILICO, POLIVINILPIRROLIDONA, N - METIL - 2 - PIRROLIDONA EN UNA PROPORCION DE UN 40 - 65 % (V/P) DEL FORMULADO TOTAL, Y GLICERINA HASTA COMPLETAR UN 100 % DE PESO FINAL. EL PROCEDIMIENTO PARA SU PREPARACION IMPLICA MEZCLAR SUFICIENTE IVERMECTINA PARA OBTENER UNA CONCENTRACION FINAL DE APROXIMADAMENTE UN 1 % (P/P) CON ALCOHOL BENCILICO Y POLIVINILPIRROLIDONA, SEGUIDO DE LA ADICION DE LA MEZCLA A N METIL - 2 - PIRROLIDONA, ESTANDO ESTA ULTIMA EN UNA PROPORCION DESDE UN 40 - 65 % (V/P) DEL TOTAL DEL FORMULADO. LA MEZCLA SE AGITA HASTA QUE SE DISUELVE TOTALMENTE Y SE AÑADE GLICERINA HASTA QUE SE ALCANZA UN 100 % DE PESO TOTAL.
ES98200868T 1997-03-21 1998-03-17 Composicion parasiticida inyectable de larga accion y procedimiento para prepararla. Expired - Lifetime ES2173545T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AR9701168 1997-03-21

Publications (1)

Publication Number Publication Date
ES2173545T3 true ES2173545T3 (es) 2002-10-16

Family

ID=3461002

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98200868T Expired - Lifetime ES2173545T3 (es) 1997-03-21 1998-03-17 Composicion parasiticida inyectable de larga accion y procedimiento para prepararla.

Country Status (8)

Country Link
US (1) US6054140A (es)
EP (1) EP0867186B1 (es)
AT (1) ATE212849T1 (es)
AU (1) AU726556B2 (es)
DE (1) DE69803710T2 (es)
ES (1) ES2173545T3 (es)
NZ (1) NZ330005A (es)
ZA (1) ZA981925B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2753377B1 (fr) * 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
US6426333B1 (en) * 1996-09-19 2002-07-30 Merial Spot-on formulations for combating parasites
NZ335166A (en) 1999-04-14 2001-11-30 Ashmont Holdings Ltd Anthelmintic composition containing triclabendazole in at least one solvent
US6998131B2 (en) * 1996-09-19 2006-02-14 Merial Limited Spot-on formulations for combating parasites
AUPP279698A0 (en) * 1998-04-03 1998-04-30 Sunscape Developments Limited Sustained release formulation
US6340672B1 (en) 2000-02-16 2002-01-22 Phoenix Scientific, Inc. Parasiticidal formulation and a method of making this formulation
BG64140B1 (bg) * 2000-12-21 2004-02-27 "Биовет" Ад Състав за растителна защита с инсектицидно и акарицидно действие
DE10063865A1 (de) * 2000-12-21 2002-06-27 Bayer Ag Verwendung von Pyrazoloximen als Parasitizide
US20050009762A1 (en) * 2003-06-06 2005-01-13 Strobel Michael Albert Application of water and organic solvent soluble ivermectin for topical and oral use
US6627613B2 (en) 2001-07-23 2003-09-30 Michael A. Strobel Application of water and organic solvent soluble ivermectin for topical and oral use
AU2006100530B4 (en) * 2002-07-19 2006-08-03 Merial Ltd Levamisole, Avermectins or similsr in pyrrolidone solvent
NZ520295A (en) * 2002-07-19 2005-04-29 Ashmont Holdings Ltd Anthelmintic formulations comprising levamisole and either an avermectin or milbemycin
US11638714B2 (en) 2020-11-10 2023-05-02 Mountain Valley Md Inc Water dissolvable macrocyclic lactone cyclodextrin complexes
US11077134B1 (en) 2020-11-10 2021-08-03 Mountain Valley Md Inc Water dissolvable macrocyclic lactone cyclodextrin complexes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389397A (en) * 1980-08-04 1983-06-21 Merck & Co., Inc. Solubilization of ivermectin in water
NZ210505A (en) * 1983-12-22 1988-06-30 Merck & Co Inc Parasiticidal compositions containing avermectin or milbemycin derivatives
EP0298423A3 (en) * 1987-07-07 1989-10-25 Kumiai Chemical Industry Co., Ltd. Antibiotic ksb-1939 compounds and production process thereof as well as pesticidal agents containing same
DE3727648A1 (de) * 1987-08-19 1989-03-02 Bayer Ag Neue avermectin derivate, verfahren zu ihrer herstellung und ihre verwendung
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
IL98599A (en) * 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them

Also Published As

Publication number Publication date
DE69803710T2 (de) 2002-11-21
NZ330005A (en) 1999-06-29
AU726556B2 (en) 2000-11-09
US6054140A (en) 2000-04-25
ATE212849T1 (de) 2002-02-15
DE69803710D1 (de) 2002-03-21
ZA981925B (en) 1998-10-23
EP0867186B1 (en) 2002-02-06
EP0867186A1 (en) 1998-09-30
AU5936798A (en) 1998-09-24

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