ES2173545T3 - Composicion parasiticida inyectable de larga accion y procedimiento para prepararla. - Google Patents
Composicion parasiticida inyectable de larga accion y procedimiento para prepararla.Info
- Publication number
- ES2173545T3 ES2173545T3 ES98200868T ES98200868T ES2173545T3 ES 2173545 T3 ES2173545 T3 ES 2173545T3 ES 98200868 T ES98200868 T ES 98200868T ES 98200868 T ES98200868 T ES 98200868T ES 2173545 T3 ES2173545 T3 ES 2173545T3
- Authority
- ES
- Spain
- Prior art keywords
- prepare
- procedure
- injectable
- final
- long action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE DESCRIBE UNA COMPOSICION PARASITICIDA DE ACCION PROLONGADA INYECTABLE, QUE INCLUYE LA SUFICIENTE IVERMECTINA PARA LOGRAR UNA CONCENTRACION FINAL DE APROXIMADAMENTE UN 1 % (P/P), ALCOHOL BENCILICO, POLIVINILPIRROLIDONA, N - METIL - 2 - PIRROLIDONA EN UNA PROPORCION DE UN 40 - 65 % (V/P) DEL FORMULADO TOTAL, Y GLICERINA HASTA COMPLETAR UN 100 % DE PESO FINAL. EL PROCEDIMIENTO PARA SU PREPARACION IMPLICA MEZCLAR SUFICIENTE IVERMECTINA PARA OBTENER UNA CONCENTRACION FINAL DE APROXIMADAMENTE UN 1 % (P/P) CON ALCOHOL BENCILICO Y POLIVINILPIRROLIDONA, SEGUIDO DE LA ADICION DE LA MEZCLA A N METIL - 2 - PIRROLIDONA, ESTANDO ESTA ULTIMA EN UNA PROPORCION DESDE UN 40 - 65 % (V/P) DEL TOTAL DEL FORMULADO. LA MEZCLA SE AGITA HASTA QUE SE DISUELVE TOTALMENTE Y SE AÑADE GLICERINA HASTA QUE SE ALCANZA UN 100 % DE PESO TOTAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AR9701168 | 1997-03-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2173545T3 true ES2173545T3 (es) | 2002-10-16 |
Family
ID=3461002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98200868T Expired - Lifetime ES2173545T3 (es) | 1997-03-21 | 1998-03-17 | Composicion parasiticida inyectable de larga accion y procedimiento para prepararla. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6054140A (es) |
EP (1) | EP0867186B1 (es) |
AT (1) | ATE212849T1 (es) |
AU (1) | AU726556B2 (es) |
DE (1) | DE69803710T2 (es) |
ES (1) | ES2173545T3 (es) |
NZ (1) | NZ330005A (es) |
ZA (1) | ZA981925B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ335166A (en) | 1999-04-14 | 2001-11-30 | Ashmont Holdings Ltd | Anthelmintic composition containing triclabendazole in at least one solvent |
FR2753377B1 (fr) * | 1996-09-19 | 1999-09-24 | Rhone Merieux | Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides |
US6998131B2 (en) * | 1996-09-19 | 2006-02-14 | Merial Limited | Spot-on formulations for combating parasites |
US6426333B1 (en) * | 1996-09-19 | 2002-07-30 | Merial | Spot-on formulations for combating parasites |
AUPP279698A0 (en) * | 1998-04-03 | 1998-04-30 | Sunscape Developments Limited | Sustained release formulation |
US6340672B1 (en) | 2000-02-16 | 2002-01-22 | Phoenix Scientific, Inc. | Parasiticidal formulation and a method of making this formulation |
DE10063865A1 (de) * | 2000-12-21 | 2002-06-27 | Bayer Ag | Verwendung von Pyrazoloximen als Parasitizide |
BG64140B1 (bg) * | 2000-12-21 | 2004-02-27 | "Биовет" Ад | Състав за растителна защита с инсектицидно и акарицидно действие |
US20050009762A1 (en) * | 2003-06-06 | 2005-01-13 | Strobel Michael Albert | Application of water and organic solvent soluble ivermectin for topical and oral use |
US6627613B2 (en) | 2001-07-23 | 2003-09-30 | Michael A. Strobel | Application of water and organic solvent soluble ivermectin for topical and oral use |
NZ520295A (en) * | 2002-07-19 | 2005-04-29 | Ashmont Holdings Ltd | Anthelmintic formulations comprising levamisole and either an avermectin or milbemycin |
AU2006100530B4 (en) * | 2002-07-19 | 2006-08-03 | Merial Ltd | Levamisole, Avermectins or similsr in pyrrolidone solvent |
US11638714B2 (en) | 2020-11-10 | 2023-05-02 | Mountain Valley Md Inc | Water dissolvable macrocyclic lactone cyclodextrin complexes |
US11077134B1 (en) | 2020-11-10 | 2021-08-03 | Mountain Valley Md Inc | Water dissolvable macrocyclic lactone cyclodextrin complexes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4389397A (en) * | 1980-08-04 | 1983-06-21 | Merck & Co., Inc. | Solubilization of ivermectin in water |
NZ210505A (en) * | 1983-12-22 | 1988-06-30 | Merck & Co Inc | Parasiticidal compositions containing avermectin or milbemycin derivatives |
AU615921B2 (en) * | 1987-07-07 | 1991-10-17 | Kumiai Chemical Industry Co., Ltd. | Antibiotic ksb-1939 compounds and production process thereof as well as pesticidal agents containing same |
DE3727648A1 (de) * | 1987-08-19 | 1989-03-02 | Bayer Ag | Neue avermectin derivate, verfahren zu ihrer herstellung und ihre verwendung |
US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
IL98599A (en) * | 1990-06-28 | 1995-06-29 | Merck & Co Inc | Stable salts of "4-deoxy-" 4-epi-methylamino abramectin and insecticides containing them |
-
1998
- 1998-03-06 US US09/035,870 patent/US6054140A/en not_active Expired - Lifetime
- 1998-03-06 ZA ZA981925A patent/ZA981925B/xx unknown
- 1998-03-17 EP EP98200868A patent/EP0867186B1/en not_active Expired - Lifetime
- 1998-03-17 DE DE69803710T patent/DE69803710T2/de not_active Expired - Lifetime
- 1998-03-17 ES ES98200868T patent/ES2173545T3/es not_active Expired - Lifetime
- 1998-03-17 AT AT98200868T patent/ATE212849T1/de not_active IP Right Cessation
- 1998-03-18 AU AU59367/98A patent/AU726556B2/en not_active Ceased
- 1998-03-20 NZ NZ330005A patent/NZ330005A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA981925B (en) | 1998-10-23 |
NZ330005A (en) | 1999-06-29 |
US6054140A (en) | 2000-04-25 |
EP0867186A1 (en) | 1998-09-30 |
DE69803710T2 (de) | 2002-11-21 |
AU5936798A (en) | 1998-09-24 |
AU726556B2 (en) | 2000-11-09 |
ATE212849T1 (de) | 2002-02-15 |
EP0867186B1 (en) | 2002-02-06 |
DE69803710D1 (de) | 2002-03-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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